Search Results - "Sierrasesúmaga, Luis"

Respiratory syncytial virus hospitalization in children in northern Spain by Viguria, Natividad, Martínez-Baz, Iván, Moreno-Galarraga, Laura, Sierrasesúmaga, Luis, Salcedo, Blanca, Castilla, Jesús

“…Understanding respiratory syncytial virus (RSV) morbidity may help to plan health care and future vaccine recommendations. We aim to describe the…”
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Germline TP53 variants and susceptibility to osteosarcoma by Mirabello, Lisa, Yeager, Meredith, Mai, Phuong L, Gastier-Foster, Julie M, Gorlick, Richard, Khanna, Chand, Patiño-Garcia, Ana, Sierrasesúmaga, Luis, Lecanda, Fernando, Andrulis, Irene L, Wunder, Jay S, Gokgoz, Nalan, Barkauskas, Donald A, Zhang, Xijun, Vogt, Aurelie, Jones, Kristine, Boland, Joseph F, Chanock, Stephen J, Savage, Sharon A

“…The etiologic contribution of germline genetic variation to sporadic osteosarcoma is not well understood. Osteosarcoma is a sentinel cancer of Li-Fraumeni…”
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Methotrexate in Pediatric Osteosarcoma: Response and Toxicity in Relation to Genetic Polymorphisms and Dihydrofolate Reductase and Reduced Folate Carrier 1 Expression by Patiño-García, Ana, PhD, Zalacaín, Marta, PhD, Marrodán, Lucía, BSc, San-Julián, Mikel, MD, PhD, Sierrasesúmaga, Luis, MD, PhD

“…Objective To determine the influence of the genotype and the level of expression of different enzymes involved in folate metabolism on the response to and…”
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Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study by Caronia, Daniela, Patiño-Garcia, Ana, Peréz-Martínez, Antonio, Pita, Guillermo, Moreno, Leticia Tais, Zalacain-Díez, Marta, Molina, Blanca, Colmenero, Isabel, Sierrasesúmaga, Luis, Benítez, Javier, Gonzalez-Neira, Anna

“…Standard treatment for osteosarcoma patients consists of a combination of cisplatin, adriamycin, and methotrexate before surgical resection of the primary…”
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What Do We Know about Survival in Skeletally Premature Children Aged 0 to 10 Years with Ewing Sarcoma? A Multicenter 10-Year Follow-Up Study in 60 Patients by Bosma, Sarah E, van der Heijden, Lizz, Sierrasesúmaga, Luis, Merks, Hans J H M, Haveman, Lianne M, van de Sande, Michiel A J, San-Julián, Mikel

“…(1) Background: Younger age has been associated with better overall survival (OS) in Ewing sarcoma (ES), especially under the age of 10. The favorable survival…”
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Imatinib Inhibits Proliferation of Ewing Tumor Cells Mediated by the Stem Cell Factor/KIT Receptor Pathway, and Sensitizes Cells to Vincristine and Doxorubicin-Induced Apoptosis by González, Iranzu, Andreu, Enrique J, Panizo, Angel, Inogés, Susana, Fontalba, Ana, Fernández-Luna, José Luis, Gaboli, Mirella, Sierrasesúmaga, Luis, Martín-Algarra, Salvador, Pardo, Javier, Prósper, Felipe, de Alava, Enrique

“…Purpose and Experimental Design: The stem cell factor/KIT receptor loop may represent a novel target for molecular-based therapies of Ewing tumor. We analyzed…”
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Profiling of Chemonaive Osteosarcoma and Paired-Normal Cells Identifies EBF2 as a Mediator of Osteoprotegerin Inhibition to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis by PATINO-GARCIA, Ana, ZALACAIN, Marta, FOLIO, Cecilia, ZANDUETA, Carolina, SIERRASESUMAGA, Luis, SAN JULIAN, Mikel, TOLEDO, Gemma, DE LAS RIVAS, Javier, LECANDA, Fernando

“…Purpose: Osteosarcoma is the most prevalent bone tumor in children and adolescents. At present, the mechanisms of initiation, maintenance, and metastasis are…”
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Proteomic analysis of chemonaive pediatric osteosarcomas and corresponding normal bone reveals multiple altered molecular targets by Folio, Cecilia, Mora, María I, Zalacain, Marta, Corrales, Fernando J, Segura, Victor, Sierrasesúmaga, Luis, Toledo, Gemma, San-Julián, Mikel, Patiño-García, Ana

“…With a view to identify the proteins involved in transformation, metastasis or chemoresistance in pediatric osteosarcoma, we carried out a new experimental…”
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Bone mineral density and bone metabolism in children treated for bone sarcomas by RUZA, Elena, SIERRASESUMAGA, Luis, AZCONA, Cristina, PATINO-GARCIA, Ana

“…In adolescent bone sarcoma patients, bone mass acquisition is potentially compromised at a time in which it should be at a maximum. To evaluate the problem we…”
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Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients by SOTILLO-PINEIRO, Elena, SIERRASESUMAGA, Luis, PATINO-GARCIA, Ana

“…The presence of telomerase activity has been analyzed in almost all tumor types and tumor-derived cell lines. However, there are very few studies that focus on…”
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Methotrexate pharmacokinetics and survival in osteosarcoma by Aquerreta, Irene, Aldaz, Azucena, Giráldez, Joaquín, Sierrasesúmaga, Luis

“…Background The aim of this study was to analyze the relationship between exposure to high‐dose methotrexate (HDMTX) and tumor response in terms of survival in…”
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Cortactin (CTTN) overexpression in osteosarcoma correlates with advanced stage and reduced survival by Folio, Cecilia, Zalacain, Marta, Zandueta, Carolina, Ormazábal, Cristina, Sierrasesúmaga, Luis, San Julián, Mikel, de las Rivas, Javier, Toledo, Gemma, Lecanda, Fernando, Patiño-García, Ana

“…The cortactin (CTTN) gene has been found, by transcriptomic profiling, to be overexpressed in pediatric osteosarcoma. The location of CTTN at 11q13 and the…”
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Analysis of polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Iα1 genes and their relationship with height in children with bone cancer by RUZA, Elena, SOTILLO, Elena, SIERRASESUMAGA, Luis, AZCONA, Cristina, PATINO-GARCIA, Ana

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Reduced bone mineralization in adolescent survivors of malignant bone tumors: Comparison of quantitative Ultrasound and dual-energy x-ray absorptiometry by AZCONA, Cristina, BURGHARD, Ellen, RUZA, Elena, GIMENO, Juan, SIERRASESUMAGA, Luis

“…To assess bone mineralization in adolescents with bone tumors at remission using quantitative digital ultrasound (QUS) and dual-energy x-ray absorptiometry…”
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Genetic and epigenetic alterations of the cell cycle regulators and tumor suppressor genes in pediatric osteosarcomas by PATINO-GARCIA, Ana, SOTILLO PINEIRO, Elena, ZALACAIN DIEZ, Marta, GARATE ITURRIAGAGOITIA, Leire, ANTILLON KLÜSSMANN, Federico, SIERRASESUMAGA ARIZNABARRETA, Luis

“…To analyze the genetic and epigenetic alterations affecting the RB1, TP53, p16INK4, and p21WAF1 tumor suppressor genes, loss of heterozygosity (LOH) at 3q and…”
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Pharmacodynamics of high-dose methotrexate in pediatric patients by Aquerreta, I, Aldaz, A, Giraldez, J, Sierrasesumaga, L

“…OBJECTIVE: To establish a relationship between the pharmacokinetics of high-dose methotrexate (MTX) and toxicity in children of a pediatric oncology department…”
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Transient posterior encephalopathy induced by chemotherapy in children by Sánchez-Carpintero, Rocı́o, Narbona, Juan, López de Mesa, Reyes, Arbizu, Javier, Sierrasesúmaga, Luis

“…The cases of three children, 16, 12, and 12 years of age, who suffered sudden confusional state and cortical blindness lasting 12 to 30 minutes while under…”
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The genetic contribution to first psychotic episodes in children and adolescents of the child and adolescent first-episode psychosis study by Patiño-Garcia, Ana, Santos, José Luis, Paya, Beatríz, Parellada, Mara, Bombin, Igor, Sierrasesúmaga, Luis, Castro-Fornieles, Josefina, Baeza, Immaculada, González-Pinto, Ana, Graell, Montserrat, Moreno, Dolores María, Rapado-Castro, Marta, Arango, Celso

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Pediatric Meningosarcoma: Clinical Evolution and Genetic Instability by de Mesa, Reyes López, Sierrasesúmaga, Luis, de Cerain, Adela López, Calasanz, María José, Patiño-García, Ana

“…This report presents a female diagnosed with a frontoparietal interhemispheric meningosarcoma who, parallel to the clinical worsening, revealed an increase in…”
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Genome-wide association study identifies two susceptibility loci for osteosarcoma by Savage, Sharon A, Mirabello, Lisa, Wang, Zhaoming, Gastier-Foster, Julie M, Gorlick, Richard, Khanna, Chand, Flanagan, Adrienne M, Tirabosco, Roberto, Andrulis, Irene L, Wunder, Jay S, Gokgoz, Nalan, Patiño-Garcia, Ana, Sierrasesúmaga, Luis, Lecanda, Fernando, Kurucu, Nilgün, Ilhan, Inci Ergurhan, Sari, Neriman, Serra, Massimo, Hattinger, Claudia, Picci, Piero, Spector, Logan G, Barkauskas, Donald A, Marina, Neyssa, de Toledo, Silvia Regina Caminada, Petrilli, Antonio S, Amary, Maria Fernanda, Halai, Dina, Thomas, David M, Douglass, Chester, Meltzer, Paul S, Jacobs, Kevin, Chung, Charles C, Berndt, Sonja I, Purdue, Mark P, Caporaso, Neil E, Tucker, Margaret, Rothman, Nathaniel, Landi, Maria Teresa, Silverman, Debra T, Kraft, Peter, Hunter, David J, Malats, Nuria, Kogevinas, Manolis, Wacholder, Sholom, Troisi, Rebecca, Helman, Lee, Fraumeni, Joseph F, Yeager, Meredith, Hoover, Robert N, Chanock, Stephen J

“…Sharon Savage and colleagues report the results of a genome-wide association study of osteosarcoma. They identify two susceptibility loci for this primary bone…”
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