Search Results - "Sierra, S"
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Global patterns and trends in colorectal cancer incidence and mortality
Published in Gut (01-04-2017)“…The global burden of colorectal cancer (CRC) is expected to increase by 60% to more than 2.2 million new cases and 1.1 million deaths by 2030. In this study,…”
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2
Mining the Unknown: Assigning Function to Noncoding Single Nucleotide Polymorphisms
Published in Trends in genetics (01-01-2017)“…One of the formative goals of genetics research is to understand how genetic variation leads to phenotypic differences and human disease. Genome-wide…”
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Hnf4a Is Required for the Development of Cdh6-Expressing Progenitors into Proximal Tubules in the Mouse Kidney
Published in Journal of the American Society of Nephrology (01-11-2020)“…Hepatocyte NF 4α (Hnf4a) is a major regulator of renal proximal tubule (PT) development. In humans, a mutation in impairs PT functions and is associated with…”
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4
SEMplMe: a tool for integrating DNA methylation effects in transcription factor binding affinity predictions
Published in BMC bioinformatics (04-08-2022)“…Aberrant DNA methylation in transcription factor binding sites has been shown to lead to anomalous gene regulation that is strongly associated with human…”
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Evaluation of Durability of a Single Dose of the Bivalent HPV Vaccine: The CVT Trial
Published in JNCI : Journal of the National Cancer Institute (01-10-2020)“…Abstract Background The authors investigated the durability of vaccine efficacy (VE) against human papillomavirus (HPV)16 or 18 infections and antibody…”
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6
Reprogramming of trunk neural crest to a cranial crest-like identity alters their transcriptome and developmental potential
Published in Differentiation (London) (01-05-2023)“…Neural crest cells along the body axis of avian embryos differ in their developmental potential, such that the cranial neural crest forms cartilage and bone…”
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Head and neck cancer burden and preventive measures in Central and South America
Published in Cancer epidemiology (01-09-2016)“…Highlights • Central and South America are regions of high incidence rates for head and neck cancer. • Males had 4 times higher head and neck cancer rates than…”
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Molecular Modeling Predicts Novel Antibody Escape Mutations in the Respiratory Syncytial Virus Fusion Glycoprotein
Published in Journal of virology (13-07-2022)“…Monoclonal antibodies are increasingly used for the prevention and/or treatment of viral infections. One caveat of their use is the ability of viruses to…”
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Cervical cancer in Central and South America: Burden of disease and status of disease control
Published in Cancer epidemiology (01-09-2016)“…Highlights • Cervical cancer remains a major public health problem in Central and South America. • However, several countries in the region have reduced…”
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Dealkylation of Poly(methyl methacrylate) by TiCl4 Vapor Phase Infiltration (VPI) and the Resulting Chemical and Thermophysical Properties of the Hybrid Material
Published in Chemistry of materials (23-01-2024)“…This study examines the chemical reaction pathways for vapor phase infiltration (VPI) of TiCl4 into poly(methyl methacrylate) (PMMA). VPI is a processing…”
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Dealkylation of Poly(methyl methacrylate) by TiCl 4 Vapor Phase Infiltration (VPI) and the Resulting Chemical and Thermophysical Properties of the Hybrid Material
Published in Chemistry of materials (23-01-2024)“…This study examines the chemical reaction pathways for vapor phase infiltration (VPI) of TiCl into poly(methyl methacrylate) (PMMA). VPI is a processing method…”
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12
Ribosome heterogeneity results in leader sequence-mediated regulation of protein synthesis in Francisella tularensis
Published in Journal of bacteriology (26-09-2023)“…Although ribosomes are generally examined in aggregate, ribosomes can be heterogenous in composition. Evidence is accumulating that changes in ribosome…”
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13
Predicting the effects of SNPs on transcription factor binding affinity
Published in Bioinformatics (15-01-2020)“…Abstract Motivation Genome-wide association studies have revealed that 88% of disease-associated single-nucleotide polymorphisms (SNPs) reside in noncoding…”
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Herbivory Protection via Volatile Organic Compounds Is Influenced by Maize Genotype, Not Bacillus altitudinis -Enriched Bacterial Communities
Published in Frontiers in microbiology (02-05-2022)“…Belowground, plants interact with beneficial soil microbes such as plant growth-promoting rhizobacteria (PGPR). PGPR are rhizosphere bacteria that colonize…”
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Global evaluation of lineage-specific human papillomavirus capsid antigenicity using antibodies elicited by natural infection
Published in Nature communications (21-02-2024)“…Human Papillomavirus (HPV) type variants have been classified into lineages and sublineages based upon their whole genome sequence. Here we have examined the…”
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Face to face: dialogues around visual impairment
Published in European journal of special needs education (23-03-2024)Get full text
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Cancer patterns and trends in Central and South America
Published in Cancer epidemiology (01-09-2016)“…Highlights • The leading incident cancers were prostate, lung, breast, cervix, colorectal, and stomach. • These cancers were also the primary causes of cancer…”
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Lytic Cell Death Mechanisms in Human Respiratory Syncytial Virus-Infected Macrophages: Roles of Pyroptosis and Necroptosis
Published in Viruses (25-08-2020)“…Human respiratory syncytial virus (RSV) is the most common cause of viral bronchiolitis and pneumonia in infants and children worldwide. Inflammation induced…”
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Impact of climate change and early development of coffee rust – An overview of control strategies to preserve organic cultivars in Mexico
Published in The Science of the total environment (10-10-2020)“…Coffee is one of the most important commercial traded commodities in the international market, as well as the most popular beverage around the world. In…”
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Social gradient and rural-urban disparities in cancer mortality in Costa Rica
Published in Cancer epidemiology (01-08-2024)“…Data on social inequalities in cancer mortality are sparse, especially in low- and middle-income countries. We aimed to analyze the socioeconomic inequalities…”
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