Search Results - "Sierocki, Pierre"

ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights by Fougiaxis, Vasileios, He, Ben, Khan, Tuhina, Vatinel, Rodolphe, Koutroumpa, Nikoletta M., Afantitis, Antreas, Lesire, Laetitia, Sierocki, Pierre, Deprez, Benoit, Deprez-Poulain, Rebecca

“…Endoplasmic reticulum aminopeptidases ERAP1 and 2 are intracellular aminopeptidases that trim antigenic precursors and generate antigens presented by major…”
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First fragment-based screening identifies new chemotypes inhibiting ERAP1-metalloprotease by Fougiaxis, Vasileios, Barcherini, Valentina, Petrovic, Milena M., Sierocki, Pierre, Warenghem, Sandrine, Leroux, Florence, Bou Karroum, Nour, Petit-Cancelier, Fabien, Rodeschini, Vincent, Roche, Didier, Deprez, Benoit, Deprez-Poulain, Rebecca

“…Inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) by small-molecules is being eagerly investigated for the treatment of various autoimmune diseases…”
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Synthesis of novel C -nucleoside analogues bearing an anomeric cyano and a 1,2,3-triazole nucleobase as potential antiviral agents by Sierocki, Pierre, Gaillard, Krystal, Arellano Reyes, Ruben Arturo, Donnart, Chloé, Lambert, Emilie, Grosse, Sandrine, Arzel, Laurence, Tessier, Arnaud, Guillemont, Jerome, Mathé-Allainmat, Monique, Lebreton, Jacques

“…A linear sequence to access a novel series of -nucleosides bearing a quaternary carbon at the anomeric position tethered to a 4-substituted 1,2,3-triazole ring…”
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Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis by Camberlein, Virgyl, Fléau, Charlotte, Sierocki, Pierre, Li, Lenong, Gealageas, Ronan, Bosc, Damien, Guillaume, Valentin, Warenghem, Sandrine, Leroux, Florence, Rosell, Melissa, Cheng, Keguang, Medve, Laura, Prigent, Mathilde, Decanter, Myriam, Piveteau, Catherine, Biela, Alexandre, Eveque, Maxime, Dumont, Julie, Mpakali, Anastasia, Giastas, Petros, Herledan, Adrien, Couturier, Cyril, Haupenthal, Jörg, Lesire, Laetitia, Hirsch, Anna K. H., Deprez, Benoit, Stratikos, Efstratios, Bouvier, Marlene, Deprez‐Poulain, Rebecca

“…Endoplasmic reticulum aminopeptidase 2 (ERAP2) is a key enzyme involved in the trimming of antigenic peptides presented by Major Histocompatibility Complex…”
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Discovery of the First Selective Nanomolar Inhibitors of Endoplasmic Reticulum Aminopeptidase 2 by Kinetic Target‐Guided Synthesis by Camberlein, Virgyl, Fleau-Tabey, Charlotte, Sierocki, Pierre, Li, Lenong, Gealageas, Ronan, Bosc, Damien, Guillaume, Valentin, Warenghem, Sandrine, Leroux, Florence, Rosell, Melissa, Cheng, Keguang, Medve, Laura, Prigent, Mathilde, Decanter, Myriam, Piveteau, Catherine, Biela, Alexandre, Eveque, Maxime, Dumont, Julie, Mpakali, Anastasia, Giastas, Petros, Herledan, Adrien, Couturier, Cyril, Haupenthal, Jörg, Lesire, Laetitia, Hirsch, Anna, Deprez, Benoit, Stratikos, Efstratios, Bouvier, Marlene, Deprez-Poulain, Rebecca

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Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target‐Guided Synthesis by Camberlein, Virgyl, Fléau, Charlotte, Sierocki, Pierre, Li, Lenong, Gealageas, Ronan, Bosc, Damien, Guillaume, Valentin, Warenghem, Sandrine, Leroux, Florence, Rosell, Melissa, Cheng, Keguang, Medve, Laura, Prigent, Mathilde, Decanter, Myriam, Piveteau, Catherine, Biela, Alexandre, Eveque, Maxime, Dumont, Julie, Mpakali, Anastasia, Giastas, Petros, Herledan, Adrien, Couturier, Cyril, Haupenthal, Jörg, Lesire, Laetitia, Hirsch, Anna K. H., Deprez, Benoit, Stratikos, Efstratios, Bouvier, Marlene, Deprez‐Poulain, Rebecca

“…Endoplasmic reticulum aminopeptidase 2 (ERAP2) is a key enzyme involved in the trimming of antigenic peptides presented by Major Histocompatibility Complex…”
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