Search Results - "Sieren, Jered"
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SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs
Published in American journal of respiratory and critical care medicine (01-10-2016)“…Multidetector row computed tomography (MDCT) is increasingly taking a central role in identifying subphenotypes within chronic obstructive pulmonary disease…”
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Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study
Published in American journal of respiratory and critical care medicine (01-12-2018)“…Increasing awareness of the prevalence and significance of Preserved Ratio Impaired Spirometry (PRISm), alternatively known as restrictive or Global Initiative…”
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Standardizing CT lung density measure across scanner manufacturers
Published in Medical physics (Lancaster) (01-03-2017)“…Purpose Computed Tomography (CT) imaging of the lung, reported in Hounsfield Units (HU), can be parameterized as a quantitative image biomarker for the…”
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Very Low-Dose (0.15 mGy) Chest CT Protocols Using the COPDGene 2 Test Object and a Third-Generation Dual-Source CT Scanner With Corresponding Third-Generation Iterative Reconstruction Software
Published in Investigative radiology (01-01-2015)“…OBJECTIVESThe purpose of this study was to evaluate the impact of ultralow radiation dose single-energy computed tomographic (CT) acquisitions with Sn…”
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Comparison of low‐ and ultralow‐dose computed tomography protocols for quantitative lung and airway assessment
Published in Medical physics (Lancaster) (01-09-2017)“…Purpose Quantitative computed tomography (CT) measures are increasingly being developed and used to characterize lung disease. With recent advances in CT…”
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High attenuation areas on chest computed tomography in community-dwelling adults: the MESA study
Published in The European respiratory journal (01-11-2016)“…Evidence suggests that lung injury, inflammation and extracellular matrix remodelling precede lung fibrosis in interstitial lung disease (ILD). We examined…”
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The Modern Art of Reading Computed Tomography Images of the Lungs: Quantitative CT
Published in Respiration (01-01-2018)“…Lung diseases are increasing in prevalence and overall burden worldwide. To stem the tide, more and more national and international guidelines are recommending…”
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Development of Quantitative Computed Tomography Lung Protocols
Published in Journal of thoracic imaging (01-09-2013)“…The purpose of this review article is to review the process of developing optimal computed tomography (CT) protocols for quantitative lung CT (QCT). In this…”
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Association of Computed Tomography Densitometry with Disease Severity, Functional Decline, and Survival in Systemic Sclerosis-associated Interstitial Lung Disease
Published in Annals of the American Thoracic Society (01-07-2020)“…Measuring disease extent and progression of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is challenging, with recent studies suggesting…”
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Dependence of subject-specific parameters for a fast helical CT respiratory motion model on breathing rate: an animal study
Published in Physics in medicine & biology (20-02-2018)“…To determine if the parameters relating lung tissue displacement to a breathing surrogate signal in a previously published respiratory motion model vary with…”
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Disease Progression Modeling in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-02-2020)Get full text
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A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS)
Published in Medical physics (Lancaster) (01-05-2016)“…Purpose: A test object (phantom) is an important tool to evaluate comparability and stability of CT scanners used in multicenter and longitudinal studies…”
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Comparison of breathing gated CT images generated using a 5DCT technique and a commercial clinical protocol in a porcine model
Published in Medical physics (Lancaster) (01-07-2015)“…Purpose: To demonstrate that a “5DCT” technique which utilizes fast helical acquisition yields the same respiratory‐gated images as a commercial technique for…”
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Scatter Correction Associated with Dedicated Dual-source CT Hardware Improves Accuracy of Lung Air Measures
Published in Academic radiology (01-11-2013)“…Rationale and Objectives Accurate assessment of air density used to quantitatively characterize amount and distribution of emphysema in chronic obstructive…”
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Effect of lung inflation level on hyperpolarized 3He apparent diffusion coefficient measurements in never-smokers
Published in Radiology (01-08-2013)“…To evaluate the effects of lung volume differences on apparent diffusion coefficient (ADC) measurements on a regional basis, with breath holds at volumes…”
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Computed Tomography and Magnetic Resonance Imaging for Longitudinal Characterization of Lung Structure Changes in a Yucatan Miniature Pig Silicosis Model
Published in Toxicologic pathology (01-04-2016)“…Medical imaging is a rapidly advancing field enabling the repeated, noninvasive assessment of physiological structure and function. These beneficial…”
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Asthma Is a Risk Factor for Respiratory Exacerbations Without Increased Rate of Lung Function Decline
Published in Chest (01-02-2018)“…Previous investigations in adult smokers from the COPDGene Study have shown that early-life respiratory disease is associated with reduced lung function, COPD,…”
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Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities
Published in JCI insight (07-04-2016)“…Airflow obstruction is common in cystic fibrosis (CF), yet the underlying pathogenesis remains incompletely understood. People with CF often exhibit airway…”
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A process model for direct correlation between computed tomography and histopathology application in lung cancer
Published in Academic radiology (01-02-2010)“…Multimodal imaging techniques for capturing normal and diseased human anatomy and physiology are being developed to benefit patient clinical care, research,…”
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