Search Results - "Siena, M"

Localized Interleukin-12 for Cancer Immunotherapy by Nguyen, Khue G, Vrabel, Maura R, Mantooth, Siena M, Hopkins, Jared J, Wagner, Ethan S, Gabaldon, Taylor A, Zaharoff, David A

“…Interleukin-12 (IL-12) is a potent, pro-inflammatory type 1 cytokine that has long been studied as a potential immunotherapy for cancer. Unfortunately, IL-12's…”
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Dynamic Hydrogels from Host–Guest Supramolecular Interactions by Mantooth, Siena M., Munoz‐Robles, Brizzia G., Webber, Matthew J.

“…Hydrogel biomaterials are pervasive in biomedical use. Applications of these soft materials range from contact lenses to drug depots to scaffolds for…”
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Intratumoral delivery of immunotherapy to treat breast cancer: current development in clinical and preclinical studies by Mantooth, Siena M, Abdou, Yara, Saez-Ibañez, Ana Rosa, Upadhaya, Samik, Zaharoff, David A

“…Breast cancer poses one of the largest threats to women's health. Treatment continues to improve for all the subtypes of breast cancer, but some subtypes, such…”
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Excitons in CsPbBr3 Halide Perovskite by Peters, J. A, Liu, Z, Bulgin, O, He, Y, Klepov, V. V, De Siena, M. C, Kanatzidis, M. G, Wessels, B. W

“…Excitons in Bridgman grown halide perovskite CsPbBr3 single crystals were examined using photoluminescence (PL) spectroscopy to determine the nature of the…”
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Intranasal Delivery of Thermostable Subunit Vaccine for Cross-Reactive Mucosal and Systemic Antibody Responses Against SARS-CoV-2 by Nguyen, Khue G, Mantooth, Siena M, Vrabel, Maura R, Zaharoff, David A

“…Despite the remarkable efficacy of currently approved COVID-19 vaccines, there are several opportunities for continued vaccine development against SARS-CoV-2…”
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A Scalable and Surfactant-Free Emulsion Method for Producing Microbeads from Varied Biomass Feedstocks by Robertson, Benjamin P., Miller, Audrey J., Rott, Gerald E., Quinn, Siena M., Rahman, Ehsanur, Bachmann, Hannah R., Nistler, Abbie F., Xiong, Boya, Calabrese, Michelle A.

“…Despite national and international regulations, plastic microbeads are still widely used in personal care and consumer products (PCCPs). These exfoliants and…”
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Prevalence of liver injury and correlation with clinical outcomes in patients with COVID-19: systematic review with meta-analysis by Del Zompo, F, De Siena, M, Ianiro, G, Gasbarrini, A, Pompili, M, Ponziani, F R

“…Liver involvement of SARS-CoV-2 infection has been reported in several papers, but without homogeneous findings. We aimed to systematically review the…”
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Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas by Lallemand, D, Manent, J, Couvelard, A, Watilliaux, A, Siena, M, Chareyre, F, Lampin, A, Niwa-Kawakita, M, Kalamarides, M, Giovannini, M

“…The NF2 gene product, merlin/schwannomin, is a cytoskeleton organizer with unique growth-inhibiting activity in specific cell types. A narrow spectrum of…”
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Rapamycin, but not minocycline, significantly alters ultrasonic vocalization behavior in C57BL/6J pups in a flurothyl seizure model by Hodges, Samantha L., Womble, Paige D., Kwok, Eliesse M., Darner, Alyssa M., Senger, Savannah S., Binder, Matthew S., Faust, Amanda M., Condon, Siena M., Nolan, Suzanne O., Quintero, Saul I., Lugo, Joaquin N.

“…[Display omitted] •Early-life seizures increased ultrasonic vocalization (USV) quantity in female mice.•Rapamycin reduced USV emission and duration in both…”
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Focal Cryo-Immunotherapy with Intratumoral IL-12 Prevents Recurrence of Large Murine Tumors by Vrabel, Maura R, Schulman, Jacob A, Gillam, Francis B, Mantooth, Siena M, Nguyen, Khue G, Zaharoff, David A

“…Focal ablation technologies are routinely used in the clinical management of inoperable solid tumors but they often result in incomplete ablations leading to…”
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Bicuspid Aortic Valve in Children and Young Adults for Cardiologists and Cardiac Surgeons: State-of-the-Art of Literature Review by Nappi, Francesco, Avtaar Singh, Sanjeet Singh, de Siena, Paolo M

“…Bicuspid aortic valve disease is the most prevalent congenital heart disease, affecting up to 2% of the general population. The presentation of symptoms may…”
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Metformin versus dietary treatment in nonalcoholic hepatic steatosis: a randomized study by Garinis, G.A, Fruci, B, Mazza, A, De Siena, M, Abenavoli, S, Gulletta, E, Ventura, V, Greco, M, Abenavoli, L, Belfiore, A

“…Objective: We aimed at evaluating whether the addition of low-dose metformin to dietary treatment could be an effective approach in nondiabetic patients with…”
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High seizure load during sensitive periods of development leads to broad shifts in ultrasonic vocalization behavior in neonatal male and female C57BL/6J mice by Nolan, Suzanne O., Hodges, Samantha L., Condon, Siena M., Muhammed, Ilyasah D.A., Tomac, Lindsay A., Binder, Matthew S., Reynolds, Conner D., Lugo, Joaquin N.

“…There is increasing evidence that seizures during early development can impact ultrasonic vocalizations (USVs) emitted from neonatal mice. However, most of the…”
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Characterization of an Injectable Chitosan Hydrogel for the Tunable, Localized Delivery of Immunotherapeutics by Mantooth, Siena M, Hancock, Asher M, Thompson, Peter M, Varghese P J, George, Meritet, Danielle M, Vrabel, Maura R, Hu, Jingjie, Zaharoff, David A

“…Localized delivery of immunotherapeutics within a tumor has the potential to reduce systemic toxicities and improve treatment outcomes in cancer patients…”
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Introduction of Prenatal Oral Health into Medical Students’ Obstetrics Training by Leone, Siena M., Quinonez, Rocio B., Chuang, Alice, Begue, Amanda, Kerns, Amanda, Jackson, Jeff, Phillips, Ceib

“…The aim of this study was to examine the influence of the Prenatal Oral Health Program (pOHP) at the University of North Carolina at Chapel Hill on medical…”
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Extended power-law scaling of air permeabilities measured on a block of tuff by Siena, M, Guadagnini, A, Riva, M, Neuman, S. P

“…We use three methods to identify power-law scaling of multi-scale log air permeability data collected by Tidwell and Wilson on the faces of a laboratory-scale…”
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Increased Faecalibacterium abundance is associated with clinical improvement in patients receiving rifaximin treatment by Ponziani, F R, Scaldaferri, F, De Siena, M, Mangiola, F, Matteo, M V, Pecere, S, Petito, V, Sterbini, F Paroni, Lopetuso, L R, Masucci, L, Cammarota, G, Sanguinetti, M, Gasbarrini, A

“…Compositional and functional alterations of the gut microbiota are involved in the pathogenesis of several gastrointestinal diseases. Rifaximin is often used…”
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Safety and Pharmacokinetics of Intravesical Chitosan/Interleukin-12 Immunotherapy in Murine Bladders by Nguyen, Khue G., Wagner, Ethan S., Vrabel, Maura R., Mantooth, Siena M., Meritet, Danielle M., Zaharoff, David A.

“…BACKGROUND: Intravesical administration of interleukin 12 (IL-12) co-formulated with the biopolymer, chitosan (CS/IL-12), has demonstrated remarkable antitumor…”
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Temporal profile of care following mild traumatic brain injury: predictors of hospital admission, follow-up referral and six-month outcome by Yue, John K., Winkler, Ethan A., Sharma, Sourabh, Vassar, Mary J., Ratcliff, Jonathan J., Korley, Frederick K., Seabury, Seth A., Ferguson, Adam R., Lingsma, Hester F., Deng, Hansen, Meeuws, Sacha, Adeoye, Opeolu M., Rick, Jonathan W., Robinson, Caitlin K., Duarte, Siena M., Yuh, Esther L., Mukherjee, Pratik, Dikmen, Sureyya S., McAllister, Thomas W., Diaz-Arrastia, Ramon, Valadka, Alex B., Gordon, Wayne A., Okonkwo, David O., Manley, Geoffrey T.

“…Objective: To investigate the clinical management and medical follow-up of patients with mild traumatic brain injury (mTBI) presenting to emergency departments…”
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Economic Consequences of Investing in Anti-HCV Antiviral Treatment from the Italian NHS Perspective: A Real-World-Based Analysis of PITER Data by Marcellusi, Andrea, Viti, Raffaella, Kondili, Loreta A., Rosato, Stefano, Vella, Stefano, Mennini, Francesco Saverio

“…Objective We estimated the cost consequence of Italian National Health System (NHS) investment in direct-acting antiviral (DAA) therapy according to hepatitis…”
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