Search Results - "Siems, W."

Chemistry and biochemistry of lipid peroxidation products by Guéraud, F, Atalay, M, Bresgen, N, Cipak, A, Eckl, P M, Huc, L, Jouanin, I, Siems, W, Uchida, K

“…Oxidative stress and resulting lipid peroxidation is involved in various and numerous pathological states including inflammation, atherosclerosis,…”
Get more information

4-Hydroxynonenal: A membrane lipid oxidation product of medicinal interest by Poli, G., Schaur, R.J., Siems, W.G., Leonarduzzi, G.

“…A comprehensive focus on 4‐hydroxynonenal (HNE) as candidate molecule in a variety of pathophysiological conditions occurring in humans is here provided…”
Get full text

Green tea reduces body fat via upregulation of neprilysin by Muenzner, M, Tappenbeck, N, Gembardt, F, Rülke, R, Furkert, J, Melzig, M F, Siems, W-E, Brockmann, G A, Walther, T

“…Background/Objective: Consumption of green tea has become increasingly popular, particularly because of claimed reduction in body weight. We recently reported…”
Get full text

Accurate and reproducible ion mobility measurements for chemical standard evaluation by Crawford, C.L., Hauck, B.C., Tufariello, J.A., Harden, C.S, McHugh, V., Siems, W.F., Hill, H.H.

“…Chemical standards are used to calibrate ion mobility spectrometers (IMS) for accurate and precise identification of target compounds. Research over the past…”
Get full text

Electrospray Ionization High-Resolution Ion Mobility Spectrometry−Mass Spectrometry by Wu, Ching, Siems, William F, Asbury, G. Reid, Hill, Herbert H

“…A hybrid atmospheric pressure ion mobility spectrometer is described which exhibits resolving power approaching the diffusion limit for singly and multiply…”
Get full text

Erythrocyte free radical and energy metabolism by Siems, W G, Sommerburg, O, Grune, T

“…The erythrocyte is a highly specialized cell whose main functions are oxygen transport and the mediation of carbon dioxide transport. Energy production in the…”
Get more information

Improvement in Skin Elasticity in the Treatment of Cellulite and Connective Tissue Weakness by Means of Extracorporeal Pulse Activation Therapy by Christ, Christophe, Brenke, Rainer, Sattler, Gerhard, Siems, Werner, Novak, Pavel, Daser, A.

“…Extracorporeal pulse activation therapy (EPAT), also called extracorporeal acoustic wave therapy, seeks to achieve effective and long-lasting improvement of…”
Get full text

Plasticity and impact of the central renin-angiotensin system during development of ethanol dependence by SOMMER, W. H, RIMONDINI, R, MARQUITZ, M, LIDSTRÖM, J, SIEMS, W-E, BADER, M, HEILIG, M

“…Pharmacological and genetic interference with the renin-angiotensin system (RAS) seems to alter voluntary ethanol consumption. However, understanding the…”
Get full text

Oxidative stress in chronic lymphoedema by Siems, W.G., Brenke, R., Beier, A., Grune, T.

“…Background:  Chronic lymphoedema is one of the most frequent and debilitating complications after surgical and radiological tumour treatment. Prevention and…”
Get full text

High sensitivity of plasma membrane ion transport ATPases from human neutrophils towards 4-hydroxy-2,3- trans-nonenal by Siems, W, Capuozzo, E, Lucano, A, Salerno, C, Crifò, C

“…Lipid peroxidation results in release of 4-hydroxy-2,3- trans-nonenal (HNE), which is known to conjugate to specific amino acids of proteins and may alter…”
Get full text

Mass Spectrometry Identifiable Cross-Linking Strategy for Studying Protein−Protein Interactions by Tang, Xiaoting, Munske, Gerhard R, Siems, William F, Bruce, James E

“…A new mass spectrometry identifiable cross-linking strategy has been developed to study protein−protein interactions. The new cross-linker was designed to have…”
Get full text

Oxidative stress in anemia by Grune, T, Sommerburg, O, Siems, W G

“…The increased formation of reactive oxygen species under hypoxic conditions often appears paradoxical. A prooxidant shift results from changes in cellular…”
Get more information

β-Carotene breakdown products enhance genotoxic effects of oxidative stress in primary rat hepatocytes by Alija, A.J., Bresgen, N., Sommerburg, O., Langhans, C.D., Siems, W., Eckl, P.M.

“…Since it has to be expected that individuals exposed to oxidative stress who take supplements of β-carotene are simultaneously exposed to both β-carotene…”
Get full text

α-Tocopherol increases caspase-3 up-regulation and apoptosis by β-carotene cleavage products in human neutrophils by Salerno, C., Capuozzo, E., Crifò, C., Siems, W.

“…It has been found that β-carotene cleavage products (CarCP), besides having mutagenic and toxic effects on mitochondria due to their prooxidative properties,…”
Get full text

Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents by Gembardt, Florian, Sterner-Kock, Anja, Imboden, Hans, Spalteholz, Matthias, Reibitz, Franziska, Schultheiss, Heinz-Peter, Siems, Wolf-Eberhard, Walther, Thomas

“…Biochemical analysis revealed that angiotensin-converting enzyme related carboxy-peptidase (ACE2) cleaves angiotensin (Ang) II to Ang-(1–7), a heptapeptide…”
Get full text

Cytotoxic and genotoxic effects of β-carotene breakdown products on primary rat hepatocytes by Alija, A.J., Bresgen, N., Sommerburg, O., Siems, W., Eckl, P.M.

“…According to Siems and colleagues, free radical attack on β-carotene results in the formation of high amounts of cleavage products with prooxidant activities…”
Get full text

Brain natriuretic peptide predicts survival in Chagas’ disease more effectively than atrial natriuretic peptide by Heringer-Walther, S, Moreira, M C V, Wessel, N, Saliba, J L, Silvia-Barra, J, Pena, J L B, Becker, S, Siems, W E, Schultheiss, H P, Walther, T

“…Areas of extensive myocardial fibrosis and left ventricular apical aneurysms are common findings. 1 Although atrial natriuretic peptide (ANP) and brain…”
Get full text

Improved antioxidative protection in winter swimmers by Siems, W.G., Brenke, R., Sommerburg, O., Grune, T.

“…Adaptation to oxidative stress is an improved ability to resist the damaging effects of reactive oxygen species, resulting from pre-exposure to a lower dose…”
Get full text

Analysis of triacylglycerols and whole oils by matrix-assisted laser desorption/ionization time of flight mass spectrometry by Asbury, G.Reid, Al-Saad, Khalid, Siems, William F, Hannan, Richard M, Hill, Herbert H

“…Since the introduction of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry the majority of research has focused on developing analytical…”
Get full text

Oxidative stress in chronic renal failure as a cardiovascular risk factor by Siems, W, Quast, S, Carluccio, F, Wiswedel, I, Hirsch, D, Augustin, W, Hampi, H, Riehle, M, Sommerburg, O

“…Myocardial injury has been shown to be the most critical factor influencing quality of life and mortality in patients with chronic renal failure. Oxidative…”
Get more information