Search Results - "Siegmund, Christian"

Data mining algorithm for pre-processing biopharmaceutical drug product manufacturing records by Casola, Gioele, Siegmund, Christian, Mattern, Markus, Sugiyama, Hirokazu

“…•The preprocessing algorithm removes the noise from a continuously measured dataset.•The dataset is visualized as a DNA-strain and the process recipe as a gene…”
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Uncertainty‐conscious methodology for process performance assessment in biopharmaceutical drug product manufacturing by Casola, Gioele, Sugiyama, Hirokazu, Siegmund, Christian, Mattern, Markus

“…This work presents an uncertainty‐conscious methodology for the assessment of process performance—for example, run time—in the manufacturing of…”
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Approach for Multicriteria Equipment Redesign in Sterile Manufacturing of Biopharmaceuticals by Zeberli, Anicia, Casola, Gioele, Badr, Sara, Siegmund, Christian, Mattern, Markus, Sugiyama, Hirokazu

“…Purpose There is a continuous search for efficient optimization methods in the production of biopharmaceuticals, with a special focus on reducing production…”
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Data mining-based algorithm for pre-processing biopharmaceutical manufacturing records by Casola, Gioele, Siegmund, Christian, Mattern, Markus, Sugiyama, Hirokazu

“…In this work, a data mining-based algorithm is presented for the pre-processing—e.g., noise removal, batch isolation—of continuously measured historical…”
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Integrated process performance assessment considering uncertainty in biopharmaceutical manufacturing operations by Casola, Gioele, Siegmund, Christian, Mattern, Markus, Sugiyama, Hirokazu

“…In this work, an integrated and systematic methodology is presented for the assessment of process performance—e.g., run time and cost—of biopharmaceutical drug…”
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Mid-term Scheduling Model Based on State-Task-Network for Considering Plant Specific Constraints in Pharmaceutical Manufacturing by Casola, Gioele, Eberle, Lukas Gallus, Siegmund, Christian, Mattern, Markus, Sugiyama, Hirokazu

“…Scheduling is of primary importance in batch manufacturing plants and has been active in the field of process system engineering for decades. After various…”
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Photographic documentation with a mobile phone camera by Siegmund, Christian J, Niamat, Jason, Avery, Christopher M

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Transparent STERI-DRAPE cover to facilitate observation of facial nerve function during parotid surgery by Siegmund, Christian J, Niamat, Jason, Avery, Christopher M

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Corrigendum to “Transparent STERI-DRAPE cover to facilitate observation of facial nerve function during parotid surgery” [Br. J. Oral Maxillofac. Surg. 45 (2007) 86] by Siegmund, Christian J, Niamat, Jason, Avery, Christopher M

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Data-driven anomaly detection and diagnostics for changeover processes in biopharmaceutical drug product manufacturing by Zeberli, Anicia, Badr, Sara, Siegmund, Christian, Mattern, Markus, Sugiyama, Hirokazu

“…•Detection and diagnosis of anomalies in biopharmaceutical manufacturing.•Using real batch process data with challenges such as imbalance and overlap.•Use of a…”
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Implant failure caused by screw head fractures—A new type of complication in a reconstruction plate: A case report by Siegmund, Christian, Schimming, Ronald, Swaid, Sami

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Autoantibodies activating human β1-Adrenergic receptors are associated with reduced cardiac function in chronic heart failure by JAHNS, R, BOIVIN, V, SIEGMUND, C, INSELMANN, G, LOHSE, M. J, BOEGE, F

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Percolation theory, conductivity and dissolution of hydrophilic suppository bases (PEG systems) by Siegmund, Christian, Leuenberger, Hans

“…We investigated the conductivity of binary mixtures of different volume to volume ratios of liquid polyethylene glycol 200 (PEG 200) and solid PEG 6000. The…”
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Activating beta-1-adrenoceptor antibodies are not associated with cardiomyopathies secondary to valvular or hypertensive heart disease by Jahns, Roland, Boivin, Valérie, Siegmund, Christian, Boege, Fritz, Lohse, Martin J, Inselmann, Gerhard

“…OBJECTIVES We investigated whether autoantibodies against the human beta-adrenergic receptor (beta-AR) might be involved in cardiomyopathies secondary to…”
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Autoantibodies activating human (Beta1-adrenergic) receptors are associated with reduced cardiac function in chronic heart failure by Jahns, Roland, Boivin, Valerie, Siegmund, Christian, Inselmann, Gerhard

“…BACKGROUND: Autoantibodies against synthetic peptides of beta-adrenergic receptors have been observed in human cardiomyopathy. However, it has never been shown…”
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Autoantibodies Activating Human β 1 -Adrenergic Receptors Are Associated With Reduced Cardiac Function in Chronic Heart Failure by Jahns, Roland, Boivin, Valérie, Siegmund, Christian, Inselmann, Gerhard, Lohse, Martin J., Boege, Fritz

“…Background —Autoantibodies against synthetic peptides of β-adrenergic receptors have been observed in human cardiomyopathy. However, it has never been shown…”
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Probing human β1- and β2-adrenoceptors with domain-specific fusion protein antibodies by Jahns, Roland, Siegmund, Christian, Jahns, Valérie, Reiländer, Helmut, Maidhof, Armin, Müller-Esterl, Werner, Lohse, Martin J., Boege, Fritz

“…In order to generate antibodies suitable for immunological studies on β-adrenoceptors constitutively expressed at low levels in cells or tissues we have…”
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Probing human β 1- and β 2-adrenoceptors with domain-specific fusion protein antibodies by Jahns, Roland, Siegmund, Christian, Jahns, Valérie, Reiländer, Helmut, Maidhof, Armin, Müller-Esterl, Werner, Lohse, Martin J, Boege, Fritz

“…In order to generate antibodies suitable for immunological studies on β-adrenoceptors constitutively expressed at low levels in cells or tissues we have…”
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Probing human β1- and β2-adrenoceptors with domain-specific fusion protein antibodies by JAHNS, R, SIEGMUND, C, JAHNS, V, REILÄNDER, H, MAIDHOF, A, MÜLLER-ESTERL, W, LOHSE, M. J, BOEGE, F

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Aerospace Education Initiative of Hochschule Bremen by Steckemetz, B., Siegmund, C.

“…Hochschule Bremen, the University of Applied Sciences in Bremen, has started the Aerospace Education Initiative in the end of 2006. The Ministry of Education…”
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