Search Results - "Siegert, Elise"

The European Scleroderma Trials and Research group (EUSTAR) task force for the development of revised activity criteria for systemic sclerosis: derivation and validation of a preliminarily revised EUSTAR activity index by Valentini, Gabriele, Iudici, Michele, Walker, Ulrich A, Jaeger, Veronika K, Baron, Murray, Carreira, Patricia, Czirják, László, Denton, Christopher P, Distler, Oliver, Hachulla, Eric, Herrick, Ariane L, Kowal-Bielecka, Otylia, Pope, Janet, Müller-Ladner, Ulf, Riemekasten, Gabriela, Avouac, Jerome, Frerix, Marc, Jordan, Suzana, Minier, Tünde, Siegert, Elise, Ong, Voon H, Vettori, Serena, Allanore, Yannick

“…Validity of European Scleroderma Study Group (EScSG) activity indexes currently used to assess disease activity in systemic sclerosis (SSc) has been…”
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Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology by Siegert, Elise, Uruha, Akinori, Goebel, Hans-Hilmar, Preuße, Corinna, Casteleyn, Vincent, Kleefeld, Felix, Alten, Rieke, Burmester, Gerd R., Schneider, Udo, Höppner, Jakob, Hahn, Kathrin, Dittmayer, Carsten, Stenzel, Werner

“…Systemic sclerosis represents a chronic connective tissue disease featuring fibrosis, vasculopathy and autoimmunity, affecting skin, multiple internal organs,…”
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The effect of omega-3 fatty acids on central nervous system remyelination in fat-1 mice by Siegert, Elise, Paul, Friedemann, Rothe, Michael, Weylandt, Karsten H

“…There is a large body of experimental evidence suggesting that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) are capable of modulating immune function…”
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Sirt1 contributes critically to the redox-dependent fate of neural progenitors by Aktas, Orhan, Glumm, Robert, Baumgart, Jan, Schröter, Friederike, Siegert, Elise, Bendix, Ivo, Schulze-Topphoff, Ulf, Nitsch, Robert, Prozorovski, Timour, Ninnemann, Olaf, Zipp, Frauke, Brüstle, Oliver

“…Repair processes that are activated in response to neuronal injury, be it inflammatory, ischaemic, metabolic, traumatic or other cause, are characterized by a…”
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Selenium and Copper as Biomarkers for Pulmonary Arterial Hypertension in Systemic Sclerosis by Sun, Qian, Hackler, Julian, Hilger, Julia, Gluschke, Hans, Muric, Aldina, Simmons, Szandor, Schomburg, Lutz, Siegert, Elise

“…Circulating selenoprotein P (SELENOP) constitutes an established biomarker of Se status. SELENOP concentrations are reduced in inflammation and severe disease…”
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Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group by Adler, Sabine, Huscher, Dörte, Siegert, Elise, Allanore, Yannick, Czirják, László, DelGaldo, Francesco, Denton, Christopher P, Distler, Oliver, Frerix, Marc, Matucci-Cerinic, Marco, Mueller-Ladner, Ulf, Tarner, Ingo-Helmut, Valentini, Gabriele, Walker, Ulrich A, Villiger, Peter M, Riemekasten, Gabriela

“…Interstitial lung disease in systemic sclerosis (SSc-ILD) is a major cause of SSc-related death. Imunosuppressive treatment (IS) is used in patients with SSc…”
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Outcomes of limited cutaneous systemic sclerosis patients: Results on more than 12,000 patients from the EUSTAR database by Frantz, Camelia, Huscher, Dorte, Avouac, Jérôme, Hachulla, Eric, Balbir-Gurman, Alexandra, Riemekasten, Gabriela, Siegert, Elise, Lazzaroni, Maria-Grazia, Carreira, Patricia E., Vettori, Serena, Zanatta, Elisabetta, Ullman, Susanne, Czirjàk, Laszlo, Kowal-Bielecka, Otylia, Distler, Oliver, Matucci-Cerinic, Marco, Allanore, Yannick

“…Limited cutaneous systemic sclerosis (LcSSc) is the most common subset of SSc but it has been overlooked in the past years. At a time at which clinical trials…”
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Comprehensive autoantibody profiles in systemic sclerosis: Clinical cluster analysis by Höppner, Jakob, Tabeling, Christoph, Casteleyn, Vincent, Kedor, Claudia, Windisch, Wolfram, Burmester, Gerd Rüdiger, Huscher, Dörte, Siegert, Elise

“…Systemic sclerosis (SSc) belongs to the group of connective tissue diseases and is associated with the occurrence of disease-specific autoantibodies. Although…”
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SIGLEC-1 in Systemic Sclerosis: A Useful Biomarker for Differential Diagnosis by Höppner, Jakob, Casteleyn, Vincent, Biesen, Robert, Rose, Thomas, Windisch, Wolfram, Burmester, Gerd Rüdiger, Siegert, Elise

“…Systemic Sclerosis (SSc) is a clinically heterogeneous disease that includes an upregulation of type I interferons (IFNs). The aim of this observational study…”
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Scleroderma Renal Crisis: Risk Factors for an Increasingly Rare Organ Complication by Moinzadeh, Pia, Kuhr, Kathrin, Siegert, Elise, Blank, Norbert, Sunderkoetter, Cord, Henes, Jörg, Krusche, Martin, Schmalzing, Marc, Worm, Margitta, Schmeiser, Tim, Günther, Claudia, Aberer, Elisabeth, Susok, Laura, Riemekasten, Gabriela, Kreuter, Alexander, Zeidler, Gabriele, Juche, Aaron, Hadjiski, Denitsa, Müller-Ladner, Ulf, Gaebelein-Wissing, Noemi, Distler, Jörg H W, Sárdy, Miklós, Krieg, Thomas, Hunzelmann, Nicolas

“…Scleroderma renal crisis (SRC) is a severe life-threatening manifestation in patients with systemic sclerosis (SSc). However, the knowledge about risk factors…”
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Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis by Weigold, Florian, Günther, Jeannine, Pfeiffenberger, Moritz, Cabral-Marques, Otavio, Siegert, Elise, Dragun, Duska, Philippe, Aurélie, Regensburger, Ann-Katrin, Recke, Andreas, Yu, Xinhua, Petersen, Frank, Catar, Rusan, Biesen, Robert, Hiepe, Falk, Burmester, Gerd R, Heidecke, Harald, Riemekasten, Gabriela

“…The chemokine receptors CXCR3 and CXCR4 are involved in the pathogenesis of fibrosis, a key feature of systemic sclerosis (SSc). It is hypothesized that…”
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Autoimmunity to Sphingosine-1-Phosphate-Receptors in Systemic Sclerosis and Pulmonary Arterial Hypertension by Gluschke, Hans, Siegert, Elise, Minich, Waldemar B., Hackler, Julian, Riemekasten, Gabriela, Kuebler, Wolfgang M., Simmons, Szandor, Schomburg, Lutz

“…Context Pulmonary arterial hypertension (PAH) is a frequent extracutaneous manifestation of systemic sclerosis (SSc). PAH is characterized by increased…”
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Autologous hematopoietic stem cell transplantation improves long-term survival-data from a national registry by Blank, Norbert, Schmalzing, Marc, Moinzadeh, Pia, Oberste, Max, Siegert, Elise, Müller-Ladner, Ulf, Riemekasten, Gabriela, Günther, Claudia, Kötter, Ina, Zeidler, Gabriele, Pfeiffer, Christiane, Juche, Aaron, Jandova, Ilona, Ehrchen, Jan, Susok, Laura, Schmeiser, Tim, Sunderkötter, Cord, Distler, Jörg H W, Worm, Margitta, Kreuter, Alexander, Keyßer, Gernot, Lorenz, Hanns-Martin, Krieg, Thomas, Hunzelmann, Nicolas, Henes, Jörg

“…Current recommendations on the management of systemic sclerosis (SSc) suggest that autologous hematopoietic stem cell therapy (HSCT) can be a rescue therapy…”
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Performance of ENMC and EULAR/ACR classification systems applied to a single tertiary center cohort of dermatomyositis patients by Zoske, Jan, Schneider, Udo, Siegert, Elise, Kleefeld, Felix, Preuße, Corinna, Stenzel, Werner, Hahn, Katrin

“…Abstract Background There have been numerous classification systems to diagnose corresponding myositis subtypes and select appropriate therapeutic measures…”
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Endothelin B Receptor Immunodynamics in Pulmonary Arterial Hypertension by Tabeling, Christoph, González Calera, Carla R., Lienau, Jasmin, Höppner, Jakob, Tschernig, Thomas, Kershaw, Olivia, Gutbier, Birgitt, Naujoks, Jan, Herbert, Julia, Opitz, Bastian, Gruber, Achim D., Hocher, Berthold, Suttorp, Norbert, Heidecke, Harald, Burmester, Gerd-R., Riemekasten, Gabriela, Siegert, Elise, Kuebler, Wolfgang M., Witzenrath, Martin

“…Introduction Inflammation is a major pathological feature of pulmonary arterial hypertension (PAH), particularly in the context of inflammatory conditions such…”
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Analysis of omega-3 and omega-6 fatty acid-derived lipid metabolite formation in human and mouse blood samples by Gomolka, Beate, Siegert, Elise, Blossey, Katrin, Schunck, Wolf-Hagen, Rothe, Michael, Weylandt, Karsten H.

“…▶ Low amounts of omega-3 and omega-6 fatty acid-derived lipid metabolites in native human plasma. ▶ Calcium ionophore A23187 activates lipid metabolite…”
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The Performance of Pulmonary Function Tests in Predicting Systemic Sclerosis-Interstitial Lung Disease in the European Scleroderma Trial and Research Database by Lepri, Gemma, Bruni, Cosimo, Tofani, Lorenzo, Moggi-Pignone, Alberto, Orlandi, Martina, Tomassetti, Sara, Hughes, Michael, Del Galdo, Francesco, Irace, Rosaria, Distler, Oliver, Riccieri, Valeria, Allanore, Yannick, Gheorghiu, Ana Maria, Siegert, Elise, De Vries-Bouwstra, Jeska, Hachulla, Eric, Tikly, Mohammed, Damjanov, Nemanja, Spertini, Francois, Mouthon, Luc, Hoffmann-Vold, Anna-Maria, Gabrielli, Armando, Guiducci, Serena, Matucci-Cerinic, Marco, Furst, Daniel, Bellando-Randone, Silvia, Eustar Collaborators

“…In SSc, ILD is a major cause of morbidity and mortality. We aimed to investigate the performance of DLCO (diffusing capacity of lung carbon monoxide) and FVC…”
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Are we too lenient with immunosuppression in severe cases of Systemic Sclerosis? by Siegert, Elise, Riemekasten, Gabriela

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Prediction of progression of interstitial lung disease in patients with systemic sclerosis: the SPAR model by Wu, Wanlong, Jordan, Suzana, Becker, Mike Oliver, Dobrota, Rucsandra, Maurer, Britta, Fretheim, Håvard, Ye, Shuang, Siegert, Elise, Allanore, Yannick, Hoffmann-Vold, Anna-Maria, Distler, Oliver

“…To identify the predictive clinical characteristics and establish a prediction model for the progression of mild interstitial lung disease (ILD) in patients…”
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Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus by von Spee-Mayer, Caroline, Siegert, Elise, Abdirama, Dimas, Rose, Angelika, Klaus, Anika, Alexander, Tobias, Enghard, Philipp, Sawitzki, Birgit, Hiepe, Falk, Radbruch, Andreas, Burmester, Gerd-Rüdiger, Riemekasten, Gabriela, Humrich, Jens Y

“…Defects in regulatory T cell (Treg) biology have been associated with human systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). However,…”
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