Search Results - "Siegel, R M"

The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells by Meylan, F, Hawley, E T, Barron, L, Barlow, J L, Penumetcha, P, Pelletier, M, Sciumè, G, Richard, A C, Hayes, E T, Gomez-Rodriguez, J, Chen, X, Paul, W E, Wynn, T A, McKenzie, A N J, Siegel, R M

“…The tumor necrosis factor (TNF)-family cytokine TL1A (TNFSF15) costimulates T cells and promotes diverse T cell-dependent models of autoimmune disease through…”
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Development of IgA nephropathy-like glomerulonephritis associated with Wiskott–Aldrich syndrome protein deficiency by Shimizu, M, Nikolov, N.P, Ueno, K, Ohta, K, Siegel, R.M, Yachie, A, Candotti, F

“…Abstract Wiskott–Aldrich syndrome (WAS) is a rare X-linked disorder caused by mutations in the WAS gene. Glomerulonephritis is a frequent complication,…”
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A Domain in TNF Receptors That Mediates Ligand-Independent Receptor Assembly and Signaling by Chan, Francis Ka-Ming, Chun, Hyung J., Zheng, Lixin, Siegel, Richard M., Bui, Kimmie L., Lenardo, Michael J.

“…A conserved domain in the extracellular region of the 60- and 80-kilodalton tumor necrosis factor receptors (TNFRs) was identified that mediates specific…”
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Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations by Siegel, Richard M., Frederiksen, John K., Zacharias, David A., Chan, Francis Ka-Ming, Johnson, Michele, Lynch, David, Tsien, Roger Y., Lenardo, Michael J.

“…Heterozygous mutations encoding abnormal forms of the death receptor Fas dominantly interfere with Fas-induced lymphocyte apoptosis in human autoimmune…”
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Signaling by the TNF Receptor Superfamily and T Cell Homeostasis by Chan, Francis Ka-Ming, Siegel, Richard M, Lenardo, Michael J

“…One of the hallmarks of the immune system is the constant expansion and contraction of different cell populations as a result of homeostatic immune regulation…”
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Corticocortical connections of anatomically and physiologically defined subdivisions within the inferior parietal lobule by Andersen, R A, Asanuma, C, Essick, G, Siegel, R M

“…The anatomical and functional organization of the inferior parietal lobule was investigated in macaque monkeys by using anterograde and retrograde anatomical…”
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Contribution of fungal loline alkaloids to protection from aphids in a grass-endophyte mutualism by WILKINSON, Heather H, SIEGEL, Malcolm R, BLANKENSHIP, Jimmy D, MALLORY, Allison C, BUSH, Lowell P, SCHARDL, Christopher L

“…Fungal endophytes provide grasses with enhanced protection from herbivory, drought, and pathogens. The loline alkaloids (saturated 1-aminopyrrolizidines with…”
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Factors associated with long-term weight-loss maintenance following bariatric surgery in adolescents with severe obesity by Ryder, J R, Gross, A C, Fox, C K, Kaizer, A M, Rudser, K D, Jenkins, T M, Ratcliff, M B, Kelly, A S, Kirk, S, Siegel, R M, Inge, T H

“…BACKGROUND/OBJECTIVES: Bariatric surgery produces robust weight loss, however, factors associated with long-term weight-loss maintenance among adolescents…”
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Natural killer cell expression of Ki67 is associated with elevated serum IL‐15, disease activity and nephritis in systemic lupus erythematosus by Hudspeth, K., Wang, S., Wang, J., Rahman, S., Smith, M. A., Casey, K. A., Parker, M., White, N., Zerrouki, K., Riggs, J., Ward, B., Bhat, G., Rajan, B., Naiman, B., Grady, R., Groves, C., Manna, Z., Sanjuan, M., Kolbeck, R., Hasni, S., Ettinger, R., Siegel, R. M.

“…Summary Systemic lupus erythematosus (SLE) is a complex autoimmune disorder whose pathology involves multiple immune cell types, including B and T lymphocytes…”
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Evolutionary diversification of fungal endophytes of tall fescue grass by hybridization with Epichloe species by Tsai, H.F, Liu, J.S, Staben, C, Christensen, M.J, Latch, G.C.M, Siegel, M.R, Schardl, C.L

“…The mutualistic associations of tall fescue (Festuca arundinacea) with seed-borne fungal symbionts (endophytes) are important for fitness of the grass host and…”
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The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation by Meylan, F, Song, Y-J, Fuss, I, Villarreal, S, Kahle, E, Malm, I-J, Acharya, K, Ramos, H L, Lo, L, Mentink-Kane, M M, Wynn, T A, Migone, T-S, Strober, W, Siegel, R M

“…The tumor necrosis factor (TNF)-family cytokine TL1A (TNFSF15) costimulates T cells through its receptor DR3 (TNFRSF25) and is required for autoimmune…”
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High-Resolution Optical Imaging of Functional Brain Architecture in the Awake Monkey by GRINVALD, A, FORSTIG, R. D, SIEGEL, R. M, BARTFELD, E

“…Optical imaging of the functional architecture of cortex, based on intrinsic signals, is a useful tool for the study of the development, organization, and…”
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Coevolution by Common Descent of Fungal Symbionts (Epichloe spp.) and Grass Hosts by Schardl, C. L., Leuchtmann, A., Chung, K-R, Penny, D., Siegel, M. R.

“…Epichloe species are ascomycetous fungi (family Clavicipitaceae) that are ecologically obligate symbionts of grasses. Because they can enhance host fitness by…”
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Life And Death Decisions: Secondary Complexes and Lipid Rafts in TNF Receptor Family Signal Transduction by Muppidi, Jagan R., Tschopp, Jürg, Siegel, Richard M.

“…Signaling by receptors in the TNF receptor (TNFR) superfamily mediate biological outcomes ranging from inflammation to apoptosis and other forms of programmed…”
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Fungal endophyte-infected grasses: alkaloid accumulation and aphid response by Siegel, M.R. (University of Kentucky, Lexington, KY), Latch, G.C.M, Bush, L.P, Fannin, F.F, Rowan, D.D, Tapper, B.A, Bacon, C.W, Johnson, M.C

“…The occurrence of the alkaloids N-formyl and N-acetyl loline, peramine, lotitrem B, and ergovaline and the response of aphids to plants containing these…”
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Inhibition of Thymocyte Apoptosis and Negative Antigenic Selection in bcl-2 Transgenic Mice by Siegel, Richard M., Katsumata, Makoto, Miyashita, Toshiyuki, Louie, Diane C., Greene, Mark I., Reed, John C.

“…The bcl-2 gene, which is overexpressed in human follicular B-cell lymphomas, has been found to extend cellular lifespan through inhibition of apoptosis, or…”
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Specific elimination of effector memory CD4 T cells due to enhanced Fas signaling complex formation and association with lipid raft microdomains by Ramaswamy, M, Cruz, A C, Cleland, S Y, Deng, M, Price, S, Rao, V K, Siegel, R M

“…Elimination of autoreactive CD4 + T cells through the death receptor Fas/CD95 is an important mechanism of immunological self-tolerance. Fas deficiency results…”
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The prevalence of sexually transmitted diseases in children and adolescents evaluated for sexual abuse in Cincinnati : rationale for limited STD testing in prepubertal girls by SIEGEL, R. M, SCHUBERT, C. J, MYERS, P. A, SHAPIRO, R. A

“…To determine the prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, syphilis, and human immunodeficiency virus (HIV) infection…”
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The role of Fas and related death receptors in autoimmune and other disease states by Siegel, Richard M., Fleisher, Thomas A.

“…The Fas receptor, also known as APO-1 or CD95, has emerged as a key initiator of apoptotic programmed cell death in a variety of cell types. CD4 + T cells are…”
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Humeral fractures without obvious etiologies in children less than 3 years of age : when is it abuse ? by STRAIT, R. T, SIEGEL, R. M, SHAPIRO, R. A

“…To determine the occurrence and frequency of abuse in children with humeral fractures without immediately obvious etiologies who are less than 3 years old and…”
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