Search Results - "Siegel, Jonathan B"

Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase by Kaczmarek, Elzbieta, Koziak, Katarzyna, Sévigny, Jean, Siegel, Jonathan B., Anrather, Josef, Beaudoin, Adrien R., Bach, Fritz H., Robson, Simon C.

“…Vascular ATP diphosphohydrolase (ATPDase) is a plasma membrane-bound enzyme that hydrolyses extracellular ATP and ADP to AMP. Analysis of amino acid sequences…”
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Analysis of CD39/ATP diphosphohydrolase (ATPDase) expression in endothelial cells, platelets and leukocytes by Koziak, K, Sévigny, J, Robson, S C, Siegel, J B, Kaczmarek, E

“…Purinergic signaling may influence hemostasis, inflammatory responses and apoptosis. Therefore, hydrolysis of extracellular ATP and ADP by the ATP…”
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Structural Elements and Limited Proteolysis of CD39 Influence ATP Diphosphohydrolase Activity by Schulte am Esch, Jan, Sévigny, Jean, Kaczmarek, Elzbieta, Siegel, Jonathan B, Imai, Masato, Koziak, Katarzyna, Beaudoin, Adrien R, Robson, Simon C

“…CD39, the mammalian ATP diphosphohydrolase (ATPDase), is thought to contain two transmembrane domains and five “apyrase conserved regions” (ACR) within a large…”
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EFFECT OF PORCINE ENDOTHELIAL TISSUE FACTOR PATHWAY INHIBITOR ON HUMAN COAGULATION FACTORS1 by Kopp, Christoph W., Siegel, Jonathan B., Hancock, Wayne W., Anrather, Josef, Winkler, Hans, Geczy, Carolyn L., Kaczmarek, Elzbieta, Bach, Fritz H., Robson, Simon C.

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Inhibition of T cell mitogenesis by a novel anti-CD45R monoclonal antibody by Robson, S C, Siegel, J B, Kirsch, R E

“…CD45 consists of a major family of membrane glycoproteins which have protein tyrosine phosphatase activity and regulate early activation events, progression…”
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Loss of ATP diphosphohydrolase activity with endothelial cell activation by Robson, S C, Kaczmarek, E, Siegel, J B, Candinas, D, Koziak, K, Millan, M, Hancock, W W, Bach, F H

“…Quiescent endothelial cells (EC) regulate blood flow and prevent intravascular thrombosis. This latter effect is mediated in a number of ways, including…”
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EXPRESSION OF HUMAN THROMBOMODULIN COFACTOR ACTIVITY IN PORCINE ENDOTHELIAL CELLS1,2 by Kopp, Christoph W., Grey, Shane T., Siegel, Jonathan B., McShea, Andrew, Vetr, Helga, Wrighton, Christopher J., Schulte Esch, Jan, Bach, Fritz H., Robson, Simon C.

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Disseminated intravascular coagulation in association with the delayed rejection of pig-to-baboon renal xenografts by IERINO, F. L, KOZLOWSKI, T, ROBSON, S. C, SIEGEL, J. B, SHIMIZU, A, COLVIN, R. B, BANERJEE, P. T, COOPER, D. K. C, COSIMI, A. B, BACH, F. H, SACHS, D. H

“…Intravascular fibrin deposition and platelet sequestration occur with porcine xenograft rejection by baboons. Disseminated intravascular coagulopathy may arise…”
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Activation of Human Platelets by the Membrane-Expressed A1 Domain of von Willebrand Factor by Schulte am Esch, Jan, Cruz, Miguel A., Siegel, Jonathan B., Anrather, Josef, Robson, Simon C.

“…Platelet activation and microthrombus formation are invariable features of xenograft rejection and the vascular injury observed when porcine organs are…”
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Xenogeneic endothelial cells activate human prothrombin by SIEGEL, J. B, GREY, S. T, LESNIKOSKI, B.-A, KOPP, C. W, SOARES, M, SCHULTE AM ESCH, J. II, BACH, F. H, ROBSON, S. C

“…Delayed xenograft rejection is characterized by platelet activation and fibrin deposition and is thought to occur independently of complement activation. We…”
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Effect of porcine endothelial tissue factor pathway inhibitor on human coagulation factors by KOPP, C. W, SIEGEL, J. B, HANCOCK, W. W, ANRATHER, J, WINKLER, H, GECZY, C. L, KACZMAREK, E, BACH, F. H, ROBSON, S. C

“…Delayed xenograft rejection (DXR) is characterized by inflammation and vascular thrombosis. Activation of coagulation may occur as a result of tissue factor…”
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Expression of human thrombomodulin cofactor activity in porcine endothelial cells by KOPP, C. W, GREY, S. T, SIEGEL, J. B, MCSHEA, A, VETR, H, WRIGHTON, C. J, AM ESCH, J. S, BACH, F. H, ROBSON, S. C

“…Xenograft rejection may predispose to vascular thrombosis because of putative cross-species' functional incompatibilities between natural anticoagulants…”
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Regulation of monocyte tissue factor activity by allogeneic and xenogeneic endothelial cells by Kopp, C W, Robson, S C, Siegel, J B, Anrather, J, Winkler, H, Grey, S, Kaczmarek, E, Bach, F H, Geczy, C L

“…The regulation of tissue factor (TF) activity by the cell associated tissue factor pathway inhibitor (TFPI) during monocyte (Mo) and endothelial cell (EC)…”
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XENOGENEIC ENDOTHELIAL CELLS ACTIVATE HUMAN PROTHROMBIN1,2 by Siegel, Jonathan B., Grey, Shane T., Lesnikoski, Beth-Ann, Kopp, Christoph W., Soares, Miguel, Esch, Jan Schulte, Bach, Fritz H., Robson, Simon C.

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Activation of human platelets by the membrane-expressed A1 domain of von Willebrand factor by SCHULTE AM ESCH, J. II, CRUZ, M. A, SIEGEL, J. B, ANRATHER, J, ROBSON, S. C

“…Platelet activation and microthrombus formation are invariable features of xenograft rejection and the vascular injury observed when porcine organs are…”
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DISSEMINATED INTRAVASCULAR COAGULATION IN ASSOCIATION WITH THE DELAYED REJECTION OF PIG-TO-BABOON RENAL XENOGRAFTS by Ierino, Francesco L., Kozlowski, Tomek, Siegel, Jonathan B., Shimizu, Akira, Colvin, Robert B., Banerjee, Papia T., Cooper, David K.C., Cosimi, A. Benedict, Bach, Fritz H., Sachs, David H., Robson, Simon C.

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