Search Results - "Siegel, F L"
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1
Glutathione S-transferase isoenzymes in rat brain neurons and glia
Published in The Journal of neuroscience (01-05-1993)“…The glutathione S-transferases (GSTs) constitute a family of cytosolic isoenzymes and a structurally unrelated microsomal enzyme that is involved in the…”
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2
Effects of lead on rat kidney and liver: GST expression and oxidative stress
Published in Toxicology (Amsterdam) (17-07-1998)“…The effect of acute exposure to lead acetate on the expression of glutathione S-transferase (GST) subunits and the levels of reduced and oxidized glutathione…”
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3
A novel inhibitor of β-glucuronidase: L-aspartic acid
Published in Pediatric research (01-10-2001)“…Infants who consume casein hydrolysate formula have been shown to have lower neonatal jaundice levels than infants who consume routine formula or breast milk…”
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4
Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation
Published in The Journal of biological chemistry (25-09-1983)“…Exogenous unlabeled arachidonic acid (AA) added to human platelets prelabeled with [3H]AA induces breakdown of [3H]phosphatidylinositol and the rapid and…”
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5
Tissue distribution of enzymic methylation of glutathione S-transferase and its effects on catalytic activity : methylation of glutathione S-transferase 11-11 inhibits conjugating activity towards 1-chloro-2,4-dinitrobenzene
Published in Biochemical journal (15-02-1992)“…Glutathione S-transferases (GSTs) were isolated from rat liver, lung, heart, kidney, testis and brain by coupled affinity chromatography and subunits were…”
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6
Trimethyllysine and protein function. Effect of methylation and mutagenesis of lysine 115 of calmodulin on NAD kinase activation
Published in The Journal of biological chemistry (05-02-1986)“…Unmethylated calmodulins have been enzymatically methylated at lysine 115, and a direct effect of this methylation on NAD kinase activation has been shown…”
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7
Effects of Lead on Glutathione S-Transferase Expression in Rat Kidney: A Dose—Response Study
Published in Toxicological sciences (01-12-1998)“…Glutathione S-transferases (GST, EC 2.5.1.18) are a family of phase II detoxification enzymes involved in the conjugation of glutathione to a highly diverse…”
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8
Maturation of cochlear glutathione- S-transferases correlates with the end of the sensitive period for ototoxicity
Published in Hearing research (01-11-1999)“…The developing mammalian cochlea is especially sensitive to chemical toxins. In rats, the period of increased sensitivity falls roughly between postnatal days…”
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9
Increased immunoreactivity of glutathione-S-transferase in the retina of Swiss Webster mice following inhalation of JP8 + 100 aerosol
Published in Archives of toxicology (01-07-2000)“…The current study was designed to determine whether exposure of mice to aerosolized jet fuel (JP8 + 100) resulted in changes in the cellular distribution or…”
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10
Shape change induced in human platelets by platelet-activating factor. Correlation with the formation of phosphatidic acid and phosphorylation of a 40,000-dalton protein
Published in The Journal of biological chemistry (25-06-1983)“…Washed human platelets that have been separated from plasma in the presence of prostacyclin are activated by the addition of platelet activating factor (PAF)…”
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11
Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn rat
Published in Biochemical journal (15-04-1993)“…The glutathione S-transferases (GSTs) are a family of isoenzymes involved in the detoxication of a variety of electrophilic xenobiotics. The present…”
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12
Influence of glutathione S-transferases on cellular glutathione determination by flow cytometry using monochlorobimane
Published in Cancer research (Chicago, Ill.) (01-04-1991)“…Intracellular glutathione (GSH) levels for seven mammalian cell lines (four human tumors, two rodent, one monkey) were determined by flow cytometry following…”
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13
Effects of triethyl lead administration on the expression of glutathione S-transferase isoenzymes and quinone reductase in rat kidney and liver
Published in Toxicology (Amsterdam) (14-02-1997)“…The effects of triethyl lead chloride (TEL) on the expression of two detoxication enzyme families, glutathione S-transferases (GSTs) and NAD(P)H:quinone…”
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14
Calmodulin N-methyltransferase. Partial purification and characterization
Published in The Journal of biological chemistry (25-05-1986)“…The distribution, properties, and substrate specificity of S-adenosylmethionine:calmodulin (lysine) N-methyltransferse (EC 2.1.1.60, calmodulin…”
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15
Translocation of nascent non-signal sequence protein in heated Escherichia coli
Published in The Journal of biological chemistry (15-06-1986)“…Exposure of Escherichia coli to heat resulted in 1) selective inhibition of protein synthesis, 2) synthesis of heat shock proteins, and 3) altered subcellular…”
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16
Characterization of methylation of rat liver cytosolic glutathione S-transferases by using reverse-phase h.p.l.c. and chromatofocusing
Published in Biochemical journal (01-09-1990)“…Glutathione S-transferase (GST) subunits in rat liver cytosol were separated by reverse-phase h.p.l.c.; five major proteins were isolated and identified as…”
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17
Protein methylation in cerebellar synaptosomes
Published in Journal of neurochemistry (01-04-1993)“…Synaptosomes from five regions of adult rat brain were isolated, analyzed for methyl acceptor proteins, and probed for methyltransferases by photoaffinity…”
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18
Proteins of muscle subcellular fractions in Duchenne progressive muscular dystrophy stained with "stains-all" cationic carbocyanine dye and with Coomassie Blue
Published in Muscle & nerve (01-04-1989)“…The protein compositions of subcellular fractions of muscle obtained from 17 Duchenne dystrophy patients, 15 disease controls (10 different primary myopathies,…”
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19
Effects of Lead Administration on Developing Rat Kidney: II. Functional, Morphologic, and Immunohistochemical Studies
Published in Toxicology and applied pharmacology (01-03-1995)“…The effects of chronic lead administration on renal function and cytoarchitecture and on the immunohistochemical localization of glutathione S-transferase…”
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20
Enzymatic methylation of calmodulin in rat brain cytosol
Published in The Journal of biological chemistry (25-09-1980)“…The methylation of brain peptides was investigated by incubating brain high speed supernatant fractions with S-adenosyl-L-[methyl-3H]methionine and resolving…”
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