Search Results - "Siegbert Rieg"
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Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants
Published in Nature communications (04-11-2021)“…The origin of SARS-CoV-2 variants of concern remains unclear. Here, we test whether intra-host virus evolution during persistent infections could be a…”
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2
Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells
Published in Nature medicine (01-01-2021)“…Emerging data indicate that SARS-CoV-2-specific CD8 + T cells targeting different viral proteins are detectable in up to 70% of convalescent individuals 1 – 5…”
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3
Health care utilisation of asylum seekers and refugees in the South-West of Germany
Published in PloS one (18-04-2024)“…Limited evidence on utilisation of health care by recently arrived asylum seekers and refugees in high-income countries is available. This study aims to…”
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4
COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation
Published in Nature communications (08-08-2022)“…Immunization with two mRNA vaccine doses elicits robust spike-specific CD8 + T cell responses, but reports of waning immunity after COVID-19 vaccination prompt…”
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5
Infectious diseases consultations can make the difference: a brief review and a plea for more infectious diseases specialists in Germany
Published in Infection (01-04-2016)“…Trained infectious diseases (ID) specialists are an integral part of inpatient and outpatient care in many countries, however, these specialized services are…”
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Clinical outcomes in patients with chronic limb-threatening ischemia and infected ulcers following endovascular therapy are pathogen dependent: A single-center experience from 2012 to 2021
Published in Vascular medicine (London, England) (01-12-2024)“…Background: Patients with chronic limb-threatening ischemia (CLTI) and infected leg ulcers are at risk of amputation and postinterventional sepsis. Methods:…”
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COVID-19 in-hospital mortality and mode of death in a dynamic and non-restricted tertiary care model in Germany
Published in PloS one (12-11-2020)“…Reported mortality of hospitalised Coronavirus Disease-2019 (COVID-19) patients varies substantially, particularly in critically ill patients. So far COVID-19…”
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Imported Toxigenic Corynebacterium Diphtheriae in Refugees with Polymicrobial Skin Infections, Germany, 2022
Published in Emerging infectious diseases (01-10-2023)“…During August–December 2022, toxigenic Corynebacterium diphtheriae was isolated from 25 refugees with skin infections and 2 refugees with asymptomatic throat…”
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Cerebral microstructural alterations in Post-COVID-condition are related to cognitive impairment, olfactory dysfunction and fatigue
Published in Nature communications (18-05-2024)“…After contracting COVID-19, a substantial number of individuals develop a Post-COVID-Condition, marked by neurologic symptoms such as cognitive deficits,…”
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10
Staphylococcus aureus bloodstream infection: A pooled analysis of five prospective, observational studies
Published in The Journal of infection (01-03-2014)“…Summary Objectives Staphylococcus aureus bacteraemia is a common, often fatal infection. Our aim was to describe how its clinical presentation varies between…”
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Extracorporeal membrane oxygenation in Pneumocystis jirovecii pneumonia: outcome in HIV and non-HIV patients
Published in Critical care (London, England) (14-11-2019)“…Keywords: Extracorporeal membrane oxygenation, Pneumocystis jirovecii, Acute respiratory distress syndrome, Outcome…”
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12
First results of the “Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS)”
Published in Infection (01-02-2021)“…Purpose Knowledge regarding patients’ clinical condition at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection is sparse. Data in the…”
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13
Patients’ with asplenia and doctors’ experiences in implementing preventative measures following a novel educational intervention: a qualitative analysis
Published in BMJ open (08-11-2022)“…ObjectiveTo explore patients’ with asplenia and general practitioners’ (GPs) (1) perceptions of a novel, Health Action Process Approach (HAPA)-based,…”
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14
Therapy with lopinavir/ritonavir and hydroxychloroquine is associated with acute kidney injury in COVID-19 patients
Published in PloS one (11-05-2021)“…Acute kidney injury (AKI) is an independent risk factor for mortality, which affects about 5% of hospitalized coronavirus disease-2019 (COVID-19) patients and…”
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15
Elevated markers of thrombo-inflammatory activation predict outcome in patients with cardiovascular comorbidities and COVID-19 disease: insights from the LEOSS registry
Published in Clinical research in cardiology (01-07-2021)“…Aims SARS-CoV-2 infection is associated with adverse outcomes in patients with cardiovascular disease. Here, we analyzed whether specific biomarkers predict…”
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16
Enterococcus faecalis bloodstream infection: does infectious disease specialist consultation make a difference?
Published in Infection (01-12-2021)“…Purpose To evaluate the relationship between mortality or relapse of bloodstream infection (BSI) due to Enterococcus faecalis and infectious diseases…”
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Comparison of different anticoagulation strategies for renal replacement therapy in critically ill patients with COVID-19: a cohort study
Published in BMC nephrology (16-11-2020)“…Critically ill coronavirus disease 2019 (COVID-19) patients have a high risk of acute kidney injury (AKI) that requires renal replacement therapy (RRT). A…”
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Prevention of post-splenectomy sepsis in patients with asplenia - a study protocol of a controlled trial
Published in BMC infectious diseases (14-01-2020)“…Patients with asplenia have a significantly increased lifelong risk of severe invasive infections, particular post-splenectomy sepsis (PSS). Clear preventive…”
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Reducing burden from respiratory infections in refugees and immigrants: a systematic review of interventions in OECD, EU, EEA and EU-applicant countries
Published in BMC infectious diseases (26-08-2021)“…Respiratory diseases are a major reason for refugees and other immigrants seeking health care in countries of arrival. The burden of respiratory diseases in…”
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Patient satisfaction & use of health care: a cross-sectional study of asylum seekers in the Freiburg initial reception centre
Published in BMC health services research (03-08-2020)“…In response to a high number of incoming asylum seekers and refugees (AS&R) in Germany, initial reception centres were established to provide immediate…”
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