Search Results - "Siedlecki, Janusz A."

The Role of SWI/SNF Chromatin Remodeling Complexes in Hormone Crosstalk by Sarnowska, Elzbieta, Gratkowska, Dominika M., Sacharowski, Sebastian P., Cwiek, Pawel, Tohge, Takayuki, Fernie, Alisdair R., Siedlecki, Janusz A., Koncz, Csaba, Sarnowski, Tomasz J.

“…SWI/SNF-type ATP-dependent chromatin remodeling complexes (CRCs) are evolutionarily conserved multiprotein machineries controlling DNA accessibility by…”
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Tumor genotype is an independent prognostic factor in primary gastrointestinal stromal tumors of gastric origin: a european multicenter analysis based on ConticaGIST by Wozniak, Agnieszka, Rutkowski, Piotr, Schöffski, Patrick, Ray-Coquard, Isabelle, Hostein, Isabelle, Schildhaus, Hans-Ulrich, Le Cesne, Axel, Bylina, Elzbieta, Limon, Janusz, Blay, Jean-Yves, Siedlecki, Janusz A, Wardelmann, Eva, Sciot, Raf, Coindre, Jean-Michel, Debiec-Rychter, Maria

“…Although the mutational status in gastrointestinal stromal tumors (GIST) can predict the response to treatment with tyrosine kinase inhibitors, the role of…”
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BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex-a tumour suppressor or tumour-promoting factor? by Jancewicz, Iga, Siedlecki, Janusz A, Sarnowski, Tomasz J, Sarnowska, Elzbieta

“…BRM (BRAHMA) is a core, SWI2/SNF2-type ATPase subunit of SWI/SNF chromatin-remodelling complex (CRC) involved in various important regulatory processes…”
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Succinate Dehydrogenase‐Deficient Renal Cancer Featuring Fructose‐1,6‐Biphosphatase Loss, Pyruvate Kinase M2 Overexpression, and SWI/SNF Chromatin Remodeling Complex Aberrations: A Rare Case Report by Szymanski, Michal, Rusetska, Natalia, Jancewicz, Iga, Armatowska, Alicja, Ligaj, Marcin, Chrzan, Alicja, Hincza, Kinga, Kowalik, Artur, Mika, Pawel, Kisiel, Maciej, Zolnierek, Jakub, Kosior, Joanna, Demkow, Tomasz, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta

“…Succinate dehydrogenase (SDH)‐deficient renal cancer is a rare renal cancer subtype recently accepted by the World Health Organization as a unique subtype of…”
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Metastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features by Przybyl, Joanna, Sciot, Raf, Wozniak, Agnieszka, Schöffski, Patrick, Vanspauwen, Vanessa, Samson, Ignace, Siedlecki, Janusz A., Rutkowski, Piotr, Debiec-Rychter, Maria

“…Synovial sarcoma (SynSa) is an aggressive mesenchymal tumor, comprising approximately 10% of all soft tissue sarcomas. Over half of SynSa patients develop…”
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Molecular Characterization and Patient Outcome of Melanoma Nodal Metastases and an Unknown Primary Site by Gos, Aleksandra, Jurkowska, Monika, van Akkooi, Alexander, Robert, Caroline, Kosela-Paterczyk, Hanna, Koljenović, Senada, Kamsukom, Nyam, Michej, Wanda, Jeziorski, Arkadiusz, Pluta, Piotr, Verhoef, Cornelis, Siedlecki, Janusz A., Eggermont, Alexander M. M., Rutkowski, Piotr

“…Background Melanoma of unknown primary site (MUP) is not a completely understood entity with nodal metastases as the most common first clinical manifestation…”
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The Search of miRNA Related to Invasive Growth of Nonfunctioning Gonadotropic Pituitary Tumors by Ostrowski, Jerzy, Siedlecki, Janusz A., Bujko, Mateusz, Kunicki, Jacek, Zeber-Lubecka, Natalia, Dąbrowska, Michalina, Paziewska, Agnieszka, Maksymowicz, Maria, Rusetska, Natalia, Kober, Paulina, Boresowicz, Joanna, Bonicki, Wiesław

“…Purpose. Nonfunctioning gonadotropic pituitary neuroendocrine tumors (PitNETs) are among the most frequent neoplasms of pituitary gland. Although PitNETs are…”
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HAX-1 overexpression, splicing and cellular localization in tumors by Trebinska, Alicja, Rembiszewska, Alina, Ciosek, Karolina, Ptaszynski, Konrad, Rowinski, Sebastian, Kupryjanczyk, Jolanta, Siedlecki, Janusz A, Grzybowska, Ewa A

“…HAX-1 has been described as a protein potentially involved in carcinogenesis and especially metastasis. Its involvement in regulation of apoptosis and cell…”
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The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study by Rutkowski, Piotr, Bylina, Elżbieta, Klimczak, Anna, Switaj, Tomasz, Falkowski, Sławomir, Kroc, Jacek, Lugowska, Iwona, Brzeskwiniewicz, Magdalena, Melerowicz, Wojciech, Osuch, Czesław, Mierzejewska, Ewa, Wasielewski, Kacper, Woźniak, Agnieszka, Grzesiakowska, Urszula, Nowecki, Zbigniew I, Siedlecki, Janusz A, Limon, Janusz

“…Gastrointestinal stromal tumors (GIST) mutational status is recognized factor related to the results of tyrosine kinase inhibitors therapy such as imatinib…”
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DNA Methylation Influences miRNA Expression in Gonadotroph Pituitary Tumors by Boresowicz, Joanna, Kober, Paulina, Rusetska, Natalia, Maksymowicz, Maria, Paziewska, Agnieszka, Dąbrowska, Michalina, Zeber-Lubecka, Natalia, Kunicki, Jacek, Bonicki, Wiesław, Ostrowski, Jerzy, Siedlecki, Janusz A, Bujko, Mateusz

“…microRNAs are involved in pathogenesis of cancer. DNA methylation plays a role in transcription of miRNA-encoding genes and may contribute to changed miRNA…”
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Recurrent and novel SS18-SSX fusion transcripts in synovial sarcoma: description of three new cases by Przybyl, Joanna, Sciot, Raf, Rutkowski, Piotr, Siedlecki, Janusz A., Vanspauwen, Vanessa, Samson, Ignace, Debiec-Rychter, Maria

“…Synovial sarcoma (SS) is an aggressive type of tumor, comprising approximately 10 % of soft tissue sarcomas. Over 90 % of SS cases are characterized by the…”
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PPARG2 Pro12Ala and TNFα -308G>A Polymorphisms Are Not Associated with Heart Failure Development in Patients with Ischemic Heart Disease after Coronary Artery Bypass Grafting by Stępińska, Janina, Siedlecki, Janusz A., Seliga, Katarzyna, Tysarowski, Andrzej, Bonda, Tomasz A., Wojtkowska, Izabela, Winnicka, Maria M.

“…TNFα and PPARγ are important modulators of metabolism, inflammation, and atherosclerosis. Coronary artery disease is the leading cause of heart failure (HF)…”
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Detection of Melanoma Cells in Lymphatic Drainage (LD) After Lymph Nodes Dissection Via Nested RT-PCR Analysis of Molecular Melanocytic Markers by Gos, Aleksandra, Rutkowski, Piotr, Siedlecki, Janusz A

“…We present the assay based on multimarker analysis of mRNA transcripts associated with melanocytic cells detected in lymphatic fluid collected after lymph node…”
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Myocardial Expression of PPARγ and Exercise Capacity in Patients after Coronary Artery Bypass Surgery by Stępińska, Janina, Piotrowicz, Ryszard, Siedlecki, Janusz A., Seliga, Katarzyna, Tysarowski, Andrzej, Osak, Jerzy, Wolszakiewicz, Jadwiga, Bonda, Tomasz A., Wojtkowska, Izabela, Winnicka, Maria M.

“…Activation of PPARs may be involved in the development of heart failure (HF). We evaluated the relationship between expression of PPARγ in the myocardium…”
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Downstream and Intermediate Interactions of Synovial Sarcoma-Associated Fusion Oncoproteins and Their Implication for Targeted Therapy by Przybyl, Joanna, Jurkowska, Monika, Rutkowski, Piotr, Debiec-Rychter, Maria, Siedlecki, Janusz A.

“…Synovial sarcoma (SS), an aggressive type of soft tissue tumor, occurs mostly in adolescents and young adults. The origin and molecular mechanism of the…”
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PPAR Gamma Expression Levels during Development of Heart Failure in Patients with Coronary Artery Disease after Coronary Artery Bypass-Grafting by Sawicki, Robert, Stępińska, Janina, Kaminski, Karol, Greszata, Lidia, Marona, Milosz, Juraszyński, Zbigniew, Siedlecki, Janusz A., Seliga, Katarzyna, Tysarowski, Andrzej, Wojtkowska, Izabela, Skrobisz, Anna

“…Genetic research has elucidated molecular mechanisms of heart failure (HF). Peroxisome proliferator-activated receptors (PPARs) seem to be important in…”
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USP8 mutations in corticotroph adenomas determine a distinct gene expression profile irrespective of functional tumour status by Bujko, Mateusz, Kober, Paulina, Boresowicz, Joanna, Rusetska, Natalia, Paziewska, Agnieszka, Dąbrowska, Michalina, Piaścik, Agata, Pękul, Monika, Zieliński, Grzegorz, Kunicki, Jacek, Bonicki, Wiesław, Ostrowski, Jerzy, Siedlecki, Janusz A, Maksymowicz, Maria

“…Objective Pituitary corticotroph adenomas commonly cause Cushing’s disease (CD) but part of these tumours are hormonally inactive (silent corticotroph…”
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SWI/SNF chromatin remodeling complex and glucose metabolism are deregulated in advanced bladder cancer by Stachowiak, Malgorzata, Szymanski, Michal, Ornoch, Anna, Jancewicz, Iga, Rusetska, Natalia, Chrzan, Alicja, Demkow, Tomasz, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta

“…Bladder cancer (BC) is a frequently diagnosed malignancy affecting predominantly adult and elderly populations. It is expected that due to the longer life…”
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Various forms of HIF‐1α protein characterize the clear cell renal cell carcinoma cell lines by Swiatek, Monika, Jancewicz, Iga, Kluebsoongnoen, Jakkapong, Zub, Renata, Maassen, Anna, Kubala, Szymon, Udomkit, Apinunt, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta

“…Renal cell carcinoma (RCC) represents around 2–3% of all malignancies diagnosed in adult patients. Most frequent (around 70–80% cases) and the most aggressive…”
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Cardiotoxicity danger in immunotherapy by Jagielska, Beata, Ozdowska, Patrycja, Gepner, Katarzyna, Kubala, Szymon, Siedlecki, Janusz A., Sarnowski, Tomasz J., Sarnowska, Elzbieta

“…Immunotherapy based on immune checkpoint inhibitors (ICIs) is currently broadly used in the treatment of different types of cancer. The treatment targeting…”
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