Search Results - "Siedlecki, James"
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Conformational Bias by a Removable Substituent. Synthesis of Eight-Membered Cyclic Ethers via Ring-Closing Metathesis
Published in Journal of the American Chemical Society (23-07-1997)Get full text
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Selective Copper-Catalyzed Coupling Reactions of (α-Acetoxyhexyl)tricyclohexyltin
Published in Journal of organic chemistry (20-09-1996)Get full text
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Synthesis of a 4-thio-2'-deoxyuridine containing oligonucleotide. Development of the thiocarbonyl group as a linker element
Published in Journal of the American Chemical Society (01-11-1992)“…We report our preliminary results on the incorporation of 4-thio-2'-deoxyuridine residues into oligodeoxynucleotides, and the development of the appendant…”
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Abstract 4297: mAbXcite: A novel immunotherapy platform that initiates a robust anti-cancer immune response by recruiting and activating neutrophils
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…The recent successes in the immunotherapy field demonstrate that a successful immune response to cancer can lead to meaningful anti-tumor responses. Antibodies…”
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The mAbXcite platform modifies the tumor microenvironment when applied to an immune-oncology anti-CTLA4 antibody
Published in Journal for immunotherapy of cancer (04-11-2015)“…The recent successes in the immunotherapy field demonstrate that a successful immune response to cancer can lead to meaningful anti-tumor responses. Antibodies…”
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mAbXcite: a novel immunotherapy platform that initiates a robust anti-cancer immune response by recruiting and activating neutrophils
Published in Journal for immunotherapy of cancer (06-11-2014)“…The recent successes in the immunotherapy field demonstrate that a successful immune response to cancer can lead to meaningful anti-tumor responses. Antibodies…”
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Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin
Published in Bioorganic & medicinal chemistry letters (01-12-2003)“…N-Acylated ornithine analogues of daptomycin were synthesized and tested for their antibacterial efficacy. N-Acylated ornithine analogues of daptomycin were…”
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Array synthesis of novel lipodepsipeptide
Published in Bioorganic & medicinal chemistry letters (01-12-2003)“…Synthetic array technology was utilized to rapidly synthesize and analyze a diverse set of reductive alkylation analogues of daptomycin. Analysis of the array…”
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Metal-mediated reactions of alpha-alkoxystannanes
Published 01-01-1997“…The ability to extend the use of $\alpha$-alkoxystannanes as synthetic intermediates requires the development of new and innovative methods for the…”
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Dissertation