Search Results - "Siebert, Janet C."

Phase 1 study of stereotactic body radiotherapy and interleukin-2--tumor and immunological responses by Seung, Steven K, Curti, Brendan D, Crittenden, Marka, Walker, Edwin, Coffey, Todd, Siebert, Janet C, Miller, William, Payne, Roxanne, Glenn, Lyn, Bageac, Alexandru, Urba, Walter J

“…Preclinical models suggest that focal high-dose radiation can make tumors more immunogenic. We performed a pilot study of stereotactic body radiation therapy…”
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The Gut Microbiota during a Behavioral Weight Loss Intervention by Stanislawski, Maggie A, Frank, Daniel N, Borengasser, Sarah J, Ostendorf, Danielle M, Ir, Diana, Jambal, Purevsuren, Bing, Kristen, Wayland, Liza, Siebert, Janet C, Bessesen, Daniel H, MacLean, Paul S, Melanson, Edward L, Catenacci, Victoria A

“…Altered gut microbiota has been linked to obesity and may influence weight loss. We are conducting an ongoing weight loss trial, comparing daily caloric…”
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CANTARE: finding and visualizing network-based multi-omic predictive models by Siebert, Janet C, Saint-Cyr, Martine, Borengasser, Sarah J, Wagner, Brandie D, Lozupone, Catherine A, Görg, Carsten

“…One goal of multi-omic studies is to identify interpretable predictive models for outcomes of interest, with analytes drawn from multiple omes. Such findings…”
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Immune Profiles to Predict Response to Desensitization Therapy in Highly HLA-Sensitized Kidney Transplant Candidates by Yabu, Julie M, Siebert, Janet C, Maecker, Holden T

“…Kidney transplantation is the most effective treatment for end-stage kidney disease. Sensitization, the formation of human leukocyte antigen (HLA) antibodies,…”
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Elevated inflammatory fecal immune factors in men who have sex with men with HIV associate with microbiome composition and gut barrier function by Littlefield, Katherine M, Schneider, Jennifer M, Neff, Charles P, Soesanto, Victoria, Siebert, Janet C, Nusbacher, Nichole M, Moreno-Huizar, Nancy, Cartwright, Ian M, Armstrong, Abigail J S, Colgen, Sean P, Lozupone, Catherine A, Palmer, Brent E

“…People living with HIV infection (PLWH) exhibit elevated levels of gastrointestinal inflammation. Potential causes of this inflammation include HIV infection…”
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Differential effects of antiretroviral treatment on immunity and gut microbiome composition in people living with HIV in rural versus urban Zimbabwe by Burkhart Colorado, Angela Sofia, Lazzaro, Alessandro, Neff, Charles Preston, Nusbacher, Nichole, Boyd, Kathryn, Fiorillo, Suzanne, Martin, Casey, Siebert, Janet C, Campbell, Thomas B, Borok, Margaret, Palmer, Brent E, Lozupone, Catherine

“…The widespread availability of antiretroviral therapy (ART) has dramatically reduced mortality and improved life expectancy for people living with HIV (PLWH)…”
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VOLARE: visual analysis of disease-associated microbiome-immune system interplay by Siebert, Janet C, Neff, Charles Preston, Schneider, Jennifer M, Regner, Emilie H, Ohri, Neha, Kuhn, Kristine A, Palmer, Brent E, Lozupone, Catherine A, Görg, Carsten

“…Relationships between specific microbes and proper immune system development, composition, and function have been reported in a number of studies. However,…”
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Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: implications for diagnosis and monitoring drug therapy by Galligan, Carole L, Siebert, Janet C, Siminovitch, Katherine A, Keystone, Edward C, Bykerk, Vivian, Perez, Omar D, Fish, Eleanor N

“…The precise mechanisms involved in the initiation and progression of rheumatoid arthritis (RA) are not known. Early stages of RA often have non-specific…”
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Novel Circulating and Tissue Monocytes as Well as Macrophages in Pancreatitis and Recovery by Manohar, Murli, Jones, Elaina K., Rubin, Samuel J.S., Subrahmanyam, Priyanka B., Swaminathan, Gayathri, Mikhail, David, Bai, Lawrence, Singh, Gulshan, Wei, Yi, Sharma, Vishal, Siebert, Janet C., Maecker, Holden T., Husain, Sohail Z., Park, Walter G., Pandol, Stephen J., Habtezion, Aida

“…Acute pancreatitis (AP) is an inflammatory disease with mild to severe course that is associated with local and systemic complications and significant…”
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The Stanford Data Miner: a novel approach for integrating and exploring heterogeneous immunological data by Siebert, Janet C, Munsil, Wes, Rosenberg-Hasson, Yael, Davis, Mark M, Maecker, Holden T

“…Systems-level approaches are increasingly common in both murine and human translational studies. These approaches employ multiple high information content…”
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Congruence as a measurement of extended haplotype structure across the genome by Baschal, Erin E, Jasinski, Jean M, Boyle, Theresa A, Fain, Pamela R, Eisenbarth, George S, Siebert, Janet C

“…Historically, extended haplotypes have been defined using only a few data points, such as alleles for several HLA genes in the MHC. High-density SNP data, and…”
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Dynamic Serial Cytokine Measurements During Intravenous Ca-DTPA Chelation in Gadolinium Deposition Disease and Gadolinium Storage Condition: A Pilot Study by Maecker, Holden T., Siebert, Janet C., Rosenberg-Hasson, Yael, Koran, Lorrin M., Ramalho, Miguel, Semelka, Richard C.

“…The aim of this study was to investigate the feasibility of measuring early changes in serum cytokine levels after intravenous diethylenetriaminepentaacetic…”
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Acute Chelation Therapy‐Associated Changes in Urine Gadolinium, Self-reported Flare Severity, and Serum Cytokines in Gadolinium Deposition Disease by Maecker, Holden T., Siebert, Janet C., Rosenberg-Hasson, Yael, Koran, Lorrin M., Ramalho, Miguel, Semelka, Richard C.

“…The aim of this study was to determine the following in patients who have undergone magnetic resonance imaging with gadolinium-based contrast agents (GBCAs)…”
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Proteomics, dietary intake, and changes in cardiometabolic health within a behavioral weight‐loss intervention: A pilot study by Hill, Emily B., Siebert, Janet C., Yazza, Deaunabah N., Ostendorf, Danielle M., Bing, Kristen, Wayland, Liza, Scorsone, Jared J., Bessesen, Daniel H., MacLean, Paul S., Melanson, Edward L., Catenacci, Victoria A., Borengasser, Sarah J.

“…Objective Identifying associations among circulating proteins, dietary intakes, and clinically relevant indicators of cardiometabolic health during weight loss…”
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Exhaustive expansion: A novel technique for analyzing complex data generated by higher-order polychromatic flow cytometry experiments by Siebert, Janet C, Wang, Lian, Haley, Daniel P, Romer, Ann, Zheng, Bo, Munsil, Wes, Gregory, Kenton W, Walker, Edwin B

“…The complex data sets generated by higher-order polychromatic flow cytometry experiments are a challenge to analyze. Here we describe Exhaustive Expansion, a…”
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Discrete Plasma Cytokine Profiles Among Pregnant Women in Botswana by Chlamydia trachomatis Infection, Human Immunodeficiency Virus Status, and Gestational Age by Babalola, Chibuzor M, Siebert, Janet C, Kallapur, Suhas G, Maecker, Holden T, Rosenberg-Hasson, Yael, Hansman, Emily, Wynn, Adriane, Mussa, Aamirah, Ryan, Rebecca, Simon, Selebaleng, Morroni, Chelsea, Klausner, Jeffrey D

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The Application of Cytokine Expression Assays to Differentiate Active From Previously Treated Syphilis by Kojima, Noah, Siebert, Janet C, Maecker, Holden, Rosenberg-Hasson, Yael, Leon, Segundo R, Vargas, Silver K, Konda, Kelika A, Caceres, Carlos F, Klausner, Jeffrey D

“…Abstract To investigate the role of serum cytokine assays to distinguish between active from treated syphilis among serofast patients, we recruited individuals…”
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Visualizing microbiome-immune system interplay by Siebert, Janet C, Görg, Carsten, Palmer, Brent, Lozupone, Catherine

“…[...]through improved understanding of particular mechanisms of interaction that impact disease and its progression, we may be able to identify particular…”
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Multiomic Predictors of Short‐Term Weight Loss and Clinical Outcomes During a Behavioral‐Based Weight Loss Intervention by Siebert, Janet C., Stanislawski, Maggie A., Zaman, Adnin, Ostendorf, Danielle M., Konigsberg, Iain R., Jambal, Purevsuren, Ir, Diana, Bing, Kristen, Wayland, Liza, Scorsone, Jared J., Lozupone, Catherine A., Görg, Carsten, Frank, Daniel N., Bessesen, Daniel, MacLean, Paul S., Melanson, Edward L., Catenacci, Victoria A., Borengasser, Sarah J.

“…Objective Identifying predictors of weight loss and clinical outcomes may increase understanding of individual variability in weight loss response. We…”
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Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy by Farsaci, Benedetto, Donahue, Renee N, Grenga, Italia, Lepone, Lauren M, Kim, Peter S, Dempsey, Brendan, Siebert, Janet C, Ibrahim, Nuhad K, Madan, Ravi A, Heery, Christopher R, Gulley, James L, Schlom, Jeffrey

“…Tumor immunoscore analyses, especially for primary colorectal cancer and melanoma lesions, provide valuable prognostic information. Metastatic lesions of many…”
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