Search Results - "Sieber, M."

Microwave Realization of the Gaussian Symplectic Ensemble by Rehemanjiang, A, Allgaier, M, Joyner, C H, Müller, S, Sieber, M, Kuhl, U, Stöckmann, H-J

“…Following an idea by Joyner et al. [Europhys. Lett. 107, 50004 (2014)], a microwave graph with an antiunitary symmetry T obeying T^{2}=-1 is realized. The…”
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FunRich: An open access standalone functional enrichment and interaction network analysis tool by Pathan, Mohashin, Keerthikumar, Shivakumar, Ang, Ching-Seng, Gangoda, Lahiru, Quek, Camelia Y.J., Williamson, Nicholas A., Mouradov, Dmitri, Sieber, Oliver M., Simpson, Richard J., Salim, Agus, Bacic, Antony, Hill, Andrew F., Stroud, David A., Ryan, Michael T., Agbinya, Johnson I., Mariadason, John M., Burgess, Antony W., Mathivanan, Suresh

“…As high‐throughput techniques including proteomics become more accessible to individual laboratories, there is an urgent need for a user‐friendly…”
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Recovery of genomes from metagenomes via a dereplication, aggregation and scoring strategy by Sieber, Christian M. K., Probst, Alexander J., Sharrar, Allison, Thomas, Brian C., Hess, Matthias, Tringe, Susannah G., Banfield, Jillian F.

“…Microbial communities are critical to ecosystem function. A key objective of metagenomic studies is to analyse organism-specific metabolic pathways and…”
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Evaluation of ultraviolet photodissociation tandem mass spectrometry for the structural assignment of unsaturated fatty acid double bond positional isomers by Fang, Mengxuan, Rustam, Yepy, Palmieri, Michelle, Sieber, Oliver M., Reid, Gavin E.

“…Fatty acids are a major source of structural diversity within the lipidome due to variations in their acyl chain lengths, branching, and cyclization, as well…”
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BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression by Barras, David, Missiaglia, Edoardo, Wirapati, Pratyaksha, Sieber, Oliver M, Jorissen, Robert N, Love, Chris, Molloy, Peter L, Jones, Ian T, McLaughlin, Stephen, Gibbs, Peter, Guinney, Justin, Simon, Iris M, Roth, Arnaud D, Bosman, Fred T, Tejpar, Sabine, Delorenzi, Mauro

“…Mutation of BRAF at the valine 600 residue occurs in approximately 10% of colorectal cancers, a group with particularly poor prognosis. The response of BRAF…”
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Isotopic fingerprinting of biogeochemical processes and iron sources in the iron-limited surface Southern Ocean by Sieber, M., Conway, T.M., de Souza, G.F., Hassler, C.S., Ellwood, M.J., Vance, D.

“…Iron (Fe) is an essential micronutrient that limits primary productivity throughout the surface of the Southern Ocean. Here, we present the first…”
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Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer by MOURADOV, Dmitri, SLOGGETT, Clare, O'CONNOR, Liam, WILDING, Jennifer L, BICKNELL, David, TOMLINSON, Ian P. M, BODMER, Walter F, MARIADASON, John M, SIEBER, Oliver M, JORISSEN, Robert N, LOVE, Christopher G, SHAN LI, BURGESS, Antony W, ARANGO, Diego, STRAUSBERG, Robert L, BUCHANAN, Daniel, WORMALD, Samuel

“…Human colorectal cancer cell lines are used widely to investigate tumor biology, experimental therapy, and biomarkers. However, to what extent these…”
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Interplay between pathway-specific and global regulation of the fumonisin gene cluster in the rice pathogen Fusarium fujikuroi by Rösler, Sarah M., Sieber, Christian M. K., Humpf, Hans-Ulrich, Tudzynski, Bettina

“…The rice pathogenic fungus Fusarium fujikuroi is known to produce a large variety of secondary metabolites. Besides the gibberellins, causing the bakanae…”
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The Fusarium graminearum genome reveals more secondary metabolite gene clusters and hints of horizontal gene transfer by Sieber, Christian M K, Lee, Wanseon, Wong, Philip, Münsterkötter, Martin, Mewes, Hans-Werner, Schmeitzl, Clemens, Varga, Elisabeth, Berthiller, Franz, Adam, Gerhard, Güldener, Ulrich

“…Fungal secondary metabolite biosynthesis genes are of major interest due to the pharmacological properties of their products (like mycotoxins and antibiotics)…”
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Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution by Dewhurst, Sally M, McGranahan, Nicholas, Burrell, Rebecca A, Rowan, Andrew J, Grönroos, Eva, Endesfelder, David, Joshi, Tejal, Mouradov, Dmitri, Gibbs, Peter, Ward, Robyn L, Hawkins, Nicholas J, Szallasi, Zoltan, Sieber, Oliver M, Swanton, Charles

“…The contribution of whole-genome doubling to chromosomal instability (CIN) and tumor evolution is unclear. We use long-term culture of isogenic tetraploid…”
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Oncomicrobial Community Profiling Identifies Clinicomolecular and Prognostic Subtypes of Colorectal Cancer by Mouradov, Dmitri, Greenfield, Paul, Li, Shan, In, Eun-Jung, Storey, Claire, Sakthianandeswaren, Anuratha, Georgeson, Peter, Buchanan, Daniel D., Ward, Robyn L., Hawkins, Nicholas J., Skinner, Iain, Jones, Ian T., Gibbs, Peter, Ma, Chenkai, Liew, Yi Jin, Fung, Kim Y.C., Sieber, Oliver M.

“…Dysbiosis of gut microbiota is linked to the development of colorectal cancer (CRC). However, microbiota-based stratification of CRC tissue and how this…”
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Distribution and Cycling of Nickel and Nickel Isotopes in the Pacific Ocean by Bian, X., Yang, S.‐C., Raad, R. J., Odendahl, C. E., Lanning, N. T., Sieber, M., Huang, K.‐F., Fitzsimmons, J. N., Conway, T. M., John, S. G.

“…Nickel stable isotopes (δ60Ni) provide insight to Ni biogeochemistry in the modern and past oceans. Here, we present the first Pacific Ocean high‐resolution…”
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Long Distance Transport of Subsurface Sediment‐Derived Iron From Asian to Alaskan Margins in the North Pacific Ocean by Sieber, M., Lanning, N. T., Steffen, J. M., Bian, X., Yang, S.‐C., Lee, J. M., Weiss, G., Hunt, H. R., Charette, M. A., Moore, W. S., Hautala, S. L., Hatta, M., Lam, P. J., John, S. G., Fitzsimmons, J. N., Conway, T. M.

“…The international GEOTRACES program has been instrumental in demonstrating how marine sediments are a critical source of dissolved Fe to the world's oceans…”
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Physical and biogeochemical controls on the distribution of dissolved cadmium and its isotopes in the Southwest Pacific Ocean by Sieber, M., Conway, T.M., de Souza, G.F., Obata, H., Takano, S., Sohrin, Y., Vance, D.

“…Cadmium stable isotope ratios (δ114Cd) have become a useful tool for oceanographers investigating the biogeochemical and physical processes that affect the…”
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Neuroprotective properties of nicotine by Sieber, M

“…Utilizing the intrinsic optical signal (IOS) of retinal Spreading Depression (rSD) waves and the concomitant transparency changes of the tissue, we show that…”
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Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically by Putoczki, Tracy L., Thiem, Stefan, Loving, Andrea, Busuttil, Rita A., Wilson, Nicholas J., Ziegler, Paul K., Nguyen, Paul M., Preaudet, Adele, Farid, Ryan, Edwards, Kirsten M., Boglev, Yeliz, Luwor, Rodney B., Jarnicki, Andrew, Horst, David, Boussioutas, Alex, Heath, Joan K., Sieber, Oliver M., Pleines, Irina, Kile, Benjamin T., Nash, Andrew, Greten, Florian R., McKenzie, Brent S., Ernst, Matthias

“…Among the cytokines linked to inflammation-associated cancer, interleukin (IL)-6 drives many of the cancer “hallmarks” through downstream activation of the…”
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The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells by Wang, Zilu, Hu, Huimin, Heitink, Luuk, Rogers, Kelly, You, Yue, Tan, Tao, Suen, Connie Li Wai, Garnham, Alex, Chen, Hao, Lieschke, Elizabeth, Diepstraten, Sarah T., Chang, Catherine, Chen, Tianwei, Moujalled, Diane, Sutherland, Kate, Lessene, Guillaume, Sieber, Oliver M., Visvader, Jane, Kelly, Gemma L., Strasser, Andreas

“…Mutant TP53 proteins are thought to drive the development and sustained expansion of cancers at least in part through the loss of the wild-type (wt) TP53…”
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Cycling of zinc and its isotopes across multiple zones of the Southern Ocean: Insights from the Antarctic Circumnavigation Expedition by Sieber, M., Conway, T.M., de Souza, G.F., Hassler, C.S., Ellwood, M.J., Vance, D.

“…Zinc (Zn) is an essential micronutrient, playing an important role in several key processes in marine phytoplankton. Here, we present the first high-resolution…”
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Deciphering the cryptic genome: genome-wide analyses of the rice pathogen Fusarium fujikuroi reveal complex regulation of secondary metabolism and novel metabolites by Wiemann, Philipp, Sieber, Christian M K, von Bargen, Katharina W, Studt, Lena, Niehaus, Eva-Maria, Espino, Jose J, Huß, Kathleen, Michielse, Caroline B, Albermann, Sabine, Wagner, Dominik, Bergner, Sonja V, Connolly, Lanelle R, Fischer, Andreas, Reuter, Gunter, Kleigrewe, Karin, Bald, Till, Wingfield, Brenda D, Ophir, Ron, Freeman, Stanley, Hippler, Michael, Smith, Kristina M, Brown, Daren W, Proctor, Robert H, Münsterkötter, Martin, Freitag, Michael, Humpf, Hans-Ulrich, Güldener, Ulrich, Tudzynski, Bettina

“…The fungus Fusarium fujikuroi causes "bakanae" disease of rice due to its ability to produce gibberellins (GAs), but it is also known for producing harmful…”
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Apicidin F: characterization and genetic manipulation of a new secondary metabolite gene cluster in the rice pathogen Fusarium fujikuroi by Niehaus, Eva-Maria, Janevska, Slavica, von Bargen, Katharina W, Sieber, Christian M K, Harrer, Henning, Humpf, Hans-Ulrich, Tudzynski, Bettina

“…The fungus F. fujikuroi is well known for its production of gibberellins causing the 'bakanae' disease of rice. Besides these plant hormones, it is able to…”
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