Search Results - "Sieben, Anne"

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD by Boeynaems, Steven, Bogaert, Elke, Michiels, Emiel, Gijselinck, Ilse, Sieben, Anne, Jovičić, Ana, De Baets, Greet, Scheveneels, Wendy, Steyaert, Jolien, Cuijt, Ivy, Verstrepen, Kevin J., Callaerts, Patrick, Rousseau, Frederic, Schymkowitz, Joost, Cruts, Marc, Van Broeckhoven, Christine, Van Damme, Philip, Gitler, Aaron D., Robberecht, Wim, Van Den Bosch, Ludo

“…Hexanucleotide repeat expansions in C9orf72 are the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) (c9ALS/FTD)…”
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The genetics and neuropathology of frontotemporal lobar degeneration by Sieben, Anne, Van Langenhove, Tim, Engelborghs, Sebastiaan, Martin, Jean-Jacques, Boon, Paul, Cras, Patrick, De Deyn, Peter-Paul, Santens, Patrick, Van Broeckhoven, Christine, Cruts, Marc

“…Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders characterized by disturbances of behavior and personality and different types of…”
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CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease by del Campo, Marta, Vermunt, Lisa, Peeters, Carel F. W., Sieben, Anne, Hok-A-Hin, Yanaika S., Lleó, Alberto, Alcolea, Daniel, van Nee, Mirrelijn, Engelborghs, Sebastiaan, van Alphen, Juliette L., Arezoumandan, Sanaz, Chen-Plotkin, Alice, Irwin, David J., van der Flier, Wiesje M., Lemstra, Afina W., Teunissen, Charlotte E.

“…Diagnosis of dementia with Lewy bodies (DLB) is challenging and specific biofluid biomarkers are highly needed. We employed proximity extension-based assays to…”
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Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients by Perrone, Federica, Nguyen, Hung Phuoc, Van Mossevelde, Sara, Moisse, Matthieu, Sieben, Anne, Santens, Patrick, De Bleecker, Jan, Vandenbulcke, Mathieu, Engelborghs, Sebastiaan, Baets, Jonathan, Cras, Patrick, Vandenberghe, Rik, De Jonghe, Peter, De Deyn, Peter P, Martin, Jean-Jacques, Van Damme, Philip, Van Broeckhoven, Christine, van der Zee, Julie

“…Abstract Mutation screening and phenotypic profiling of 2 amyotrophic lateral sclerosis–(ALS) and frontotemporal dementia–(FTD) associated genes, CHCHD10 and…”
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The Electrophysiological Correlates of Phoneme Perception in Primary Progressive Aphasia: A Preliminary Case Series by Stalpaert, Jara, Miatton, Marijke, Sieben, Anne, Van Langenhove, Tim, van Mierlo, Pieter, De Letter, Miet

“…Aims : This study aimed to investigate phoneme perception in patients with primary progressive aphasia (PPA) by using the event-related potential (ERP)…”
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NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients by Nguyen, Hung Phuoc, Van Mossevelde, Sara, Dillen, Lubina, De Bleecker, Jan L., Moisse, Matthieu, Van Damme, Philip, Van Broeckhoven, Christine, van der Zee, Julie, Engelborghs, Sebastiaan, Crols, Roeland, De Deyn, Peter P., De Jonghe, Peter, Baets, Jonathan, Cras, Patrick, Mercelis, Rudy, Vandenberghe, Rik, Sieben, Anne, Santens, Patrick, Ivanoiu, Adrian, Deryck, Olivier, Vanopdenbosch, Ludo, Delbeck, Jean

“…We evaluated the genetic impact of the amyotrophic lateral sclerosis (ALS) risk gene never in mitosis gene a–related kinase 1 (NEK1) in a Belgian cohort of 278…”
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Suprasternal Bronchogenic Cyst in an 8-Year-Old Girl by Asena Altun, Giada Bilotta, Gilles Van Haesendonck, Callum Farris, Olivier M Vanderveken, Anne Sieben, An Boudewyns

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Family-based exome sequencing identifies RBM45 as a possible candidate gene for frontotemporal dementia and amyotrophic lateral sclerosis by van der Zee, Julie, Dillen, Lubina, Baradaran-Heravi, Yalda, Gossye, Helena, Koçoğlu, Cemile, Cuyt, Ivy, Dermaut, Bart, Sieben, Anne, Baets, Jonathan, De Jonghe, Peter, Vandenberghe, Rik, De Deyn, Peter, Cras, Patrick, Engelborghs, Sebastiaan, Van Broeckhoven, Christine

“…Neurodegenerative disorders like frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are pathologically characterized by toxic protein…”
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Distinct [18F]THK5351 binding patterns in primary progressive aphasia variants by Schaeverbeke, Jolien, Evenepoel, Charlotte, Declercq, Lieven, Gabel, Silvy, Meersmans, Karen, Bruffaerts, Rose, Adamczuk, Kate, Dries, Eva, Van Bouwel, Karen, Sieben, Anne, Pijnenburg, Yolande, Peeters, Ronald, Bormans, Guy, Van Laere, Koen, Koole, Michel, Dupont, Patrick, Vandenberghe, Rik

“…Purpose To assess the binding of the PET tracer [ 18 F]THK5351 in patients with different primary progressive aphasia (PPA) variants and its correlation with…”
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Therapy-Induced Electrophysiological Changes in Primary Progressive Aphasia: A Preliminary Study by Stalpaert, Jara, Standaert, Sofie, D'Helft, Lien, Miatton, Marijke, Sieben, Anne, Van Langenhove, Tim, Duyck, Wouter, van Mierlo, Pieter, De Letter, Miet

“…This preliminary study aimed to investigate therapy-induced electrophysiological changes in persons with primary progressive aphasia (PPA). The investigated…”
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Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration by Goossens, Joery, Bjerke, Maria, Van Mossevelde, Sara, Van den Bossche, Tobi, Goeman, Johan, De Vil, Bart, Sieben, Anne, Martin, Jean-Jacques, Cras, Patrick, De Deyn, Peter Paul, Van Broeckhoven, Christine, van der Zee, Julie, Engelborghs, Sebastiaan

“…We explored the diagnostic performance of cerebrospinal fluid (CSF) biomarkers in allowing differentiation between frontotemporal lobar degeneration (FTLD) and…”
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Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson's disease by Smolders, Stefanie, Philtjens, Stéphanie, Crosiers, David, Sieben, Anne, Hens, Elisabeth, Heeman, Bavo, Van Mossevelde, Sara, Pals, Philippe, Asselbergh, Bob, Dos Santos Dias, Roberto, Vermeiren, Yannick, Vandenberghe, Rik, Engelborghs, Sebastiaan, De Deyn, Peter Paul, Martin, Jean-Jacques, Cras, Patrick, Annaert, Wim, Van Broeckhoven, Christine

“…Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) are clinically, pathologically and etiologically disorders embedded in the Lewy body disease (LBD)…”
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Brain age as a biomarker for pathological versus healthy ageing - a REMEMBER study by Wittens, Mandy M J, Denissen, Stijn, Sima, Diana M, Fransen, Erik, Niemantsverdriet, Ellis, Bastin, Christine, Benoit, Florence, Bergmans, Bruno, Bier, Jean-Christophe, de Deyn, Peter Paul, Deryck, Olivier, Hanseeuw, Bernard, Ivanoiu, Adrian, Picard, Gaëtane, Ribbens, Annemie, Salmon, Eric, Segers, Kurt, Sieben, Anne, Struyfs, Hanne, Thiery, Evert, Tournoy, Jos, van Binst, Anne-Marie, Versijpt, Jan, Smeets, Dirk, Bjerke, Maria, Nagels, Guy, Engelborghs, Sebastiaan

“…This study aimed to evaluate the potential clinical value of a new brain age prediction model as a single interpretable variable representing the condition of…”
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Amyloid-β1–43 cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations by Perrone, Federica, Bjerke, Maria, Hens, Elisabeth, Sieben, Anne, Timmers, Maarten, De Roeck, Arne, Vandenberghe, Rik, Sleegers, Kristel, Martin, Jean-Jacques, De Deyn, Peter P., Engelborghs, Sebastiaan, van der Zee, Julie, Van Broeckhoven, Christine, Cacace, Rita, Goeman, Johan, Crols, Roeland, Dermaut, Bart, Ivanoiu, Adrian, Hanseeuw, Bernard, Deryck, Olivier, Bergmans, Bruno, Versijpt, Jan, Pharmaceutica, Janssen, Saido, Takaomi

“…Abstract Background Alzheimer’s disease (AD) mutations in amyloid precursor protein ( APP ) and presenilins ( PSENs ) could potentially lead to the production…”
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Proteomic Assessment of C57BL/6 Hippocampi after Non-Selective Pharmacological Inhibition of Nitric Oxide Synthase Activity: Implications of Seizure-like Neuronal Hyperexcitability Followed by Tauopathy by Hendrickx, Jhana O, Adams, Charlotte, Sieben, Anne, Laukens, Kris, Van Dam, Debby, De Meyer, Guido R. Y

“…Nitric oxide (NO) is a small gaseous signaling molecule responsible for maintaining homeostasis in a myriad of tissues and molecular pathways in neurology and…”
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Single-word comprehension deficits in the nonfluent variant of primary progressive aphasia by Schaeverbeke, Jolien, Gabel, Silvy, Meersmans, Karen, Bruffaerts, Rose, Liuzzi, Antonietta Gabriella, Evenepoel, Charlotte, Dries, Eva, Van Bouwel, Karen, Sieben, Anne, Pijnenburg, Yolande, Peeters, Ronald, Bormans, Guy, Van Laere, Koen, Koole, Michel, Dupont, Patrick, Vandenberghe, Rik

“…A subset of patients with the nonfluent variant of primary progressive aphasia (PPA) exhibit concomitant single-word comprehension problems, constituting a…”
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Extended FTLD pedigree segregating a Belgian GRN-null mutation: neuropathological heterogeneity in one family by Sieben, Anne, Van Mossevelde, Sara, Wauters, Eline, Engelborghs, Sebastiaan, van der Zee, Julie, Van Langenhove, Tim, Santens, Patrick, Praet, Marleen, Boon, Paul, Miatton, Marijke, Van Hoecke, Sofie, Vandenbulcke, Mathieu, Vandenberghe, Rik, Cras, Patrick, Cruts, Marc, De Deyn, Peter Paul, Van Broeckhoven, Christine, Martin, Jean-Jacques

“…In this paper, we describe the clinical and neuropathological findings of nine members of the Belgian progranulin gene (GRN) founder family. In this family,…”
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No added diagnostic value of non-phosphorylated tau fraction (p-tau rel ) in CSF as a biomarker for differential dementia diagnosis by Goossens, Joery, Bjerke, Maria, Struyfs, Hanne, Niemantsverdriet, Ellis, Somers, Charisse, Van den Bossche, Tobi, Van Mossevelde, Sara, De Vil, Bart, Sieben, Anne, Martin, Jean-Jacques, Cras, Patrick, Goeman, Johan, De Deyn, Peter Paul, Van Broeckhoven, Christine, van der Zee, Julie, Engelborghs, Sebastiaan

“…The Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers Aβ , t-tau, and p-tau overlap with other diseases. New tau modifications or epitopes, such as…”
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Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease by Dekker, Alain D., Vermeiren, Yannick, Carmona-Iragui, Maria, Benejam, Bessy, Videla, Laura, Gelpi, Ellen, Aerts, Tony, Van Dam, Debby, Fernández, Susana, Lleó, Alberto, Videla, Sebastian, Sieben, Anne, Martin, Jean-Jacques, Blesa, Rafael, Fortea, Juan, De Deyn, Peter P.

“…People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but…”
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Narratives of Hope and Grief in Higher Education by Shelton, Stephanie Anne, Ed, Sieben, Nicole, Eds

“…This collection weaves together the personal narratives of a group of diverse scholars in academia in order to reflect on the ways that grief and hope matter…”
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