Search Results - "Sieb, JP"

Fatigue in multiple sclerosis is closely related to sleep disorders: a polysomnographic cross-sectional study by Veauthier, C, Radbruch, H, Gaede, G, Pfueller, CF, Dörr, J, Bellmann-Strobl, J, Wernecke, K-D, Zipp, F, Paul, F, Sieb, JP

“…Background: Sleep disorders can cause tiredness. The relationship between sleep disorders and fatigue in patients with multiple sclerosis (MS) has not yet been…”
Get full text

Iatrogenic and toxic myopathies by Sieb, Joern P., Gillessen, Thomas

“…There has been increasing awareness of the adverse effects of therapeutic agents and exogenous toxins on the structure and function of muscle. The resulting…”
Get full text

Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity by Veauthier, Christian, Gaede, Gunnar, Radbruch, Helena, Sieb, Joern-Peter, Wernecke, Klaus-Dieter, Paul, Friedemann

“…There are few studies describing periodic limb movement syndrome (PLMS) in rapid eye movement (REM) sleep in patients with narcolepsy, restless legs syndrome,…”
Get full text

Myasthenia gravis: emerging new therapy options by Sieb, Joern P

“…Myasthenia gravis is probably the most thoroughly understood of all human autoimmune diseases. The basic mechanism of the disease is an antibody-mediated…”
Get full text

Schwangerschaftsverlauf bei einer 33-jährigen Parkinson-Patientin unter hochdosierter Dopaminagonisten-Therapie und Tiefenhirnstimulation by Vogeler, FC, Sieb, JP, Ruhland, F

“…Abstract only…”
Get full text

Fluoroquinolone antibiotics block neuromuscular transmission by Sieb, J P

“…Fluorinated 4-quinolones are widely used antibiotics. Several case reports describe the exacerbation of muscle weakness in myasthenia gravis patients treated…”
Get full text

New Mutations in Acetylcholine Receptor Subunit Genes Reveal Heterogeneity in the Slow-Channel Congenital Myasthenic Syndrome by Engel, Andrew G., Ohno, Kinji, Milone, Margherita, Wang, Hai-Long, Nakano, Satoshi, Bouzat, Cecilia, Pruitt, J. Ned, Hutchinson, David O., Brengman, Joan M., Bren, Nina, Sieb, Joern P., Sine, Steven M.

“…Mutations in genes encoding the ε, δ, β and α subunits of the end plate acetylcholine (ACh) receptor (AChR) are described and functionally characterized in…”
Get full text

Novel truncating RAPSN mutations causing congenital myasthenic syndrome responsive to 3,4-diaminopyridine by Banwell, Brenda L, Ohno, Kinji, Sieb, Joern P, Engel, Andrew G

“…Rapsyn is essential for clustering the acetylcholine receptor at the postsynaptic membrane of the neuromuscular junction. Direct sequencing of RAPSN in two…”
Get full text

Alopecia induced by dopamine agonists by Grauer, Markus T, Sieb, Joern P

Get full text

Occurrence of chloroquine-induced myopathy after low-dose treatment of rheumatoid arthritis for seven years by Haberl, A, Fischer, P, Pongratz, D, Sieb, J P

“…The myotoxicity of chloroquine and hydroxychloroquine has been known for decades. Limb-girdle weakness due to a vacuolar myopathy may occur occasionally in a…”
Get full text

Effects of the quinoline derivatives quinine, quinidine, and chloroquine on neuromuscular transmission by Sieb, Jörn P., Milone, Margherita, Engel, Andrew G.

“…The quinoline derivatives quinine, its stereoisomer quinidine, and chloroquine may worsen or provoke disorders of neuromuscular transmission. In this study, we…”
Get full text

Relapsing alternating ptosis in two siblings by SIEB, J P, HARTMANN, A

Get full text

Immature end-plates and utrophin deficiency in congenital myasthenic syndrome caused by ε-AChR subunit truncating mutations by SIEB, Jörn P, KRANER, Simone, RAUCH, Michael, STEINLEIN, Ortrud K

“…Congenital myasthenic syndromes (CMS) are inborn disorders due to presynaptic, synaptic, or postsynaptic defects of neuromuscular transmission. Some previously…”
Get full text

Congenital myasthenia in Brahman calves caused by homozygosity for a CHRNE truncating mutation by KRANER, Simone, SIEB, Jörn P, THOMPSON, Peter N, STEINLEIN, Ortrud K

“…To elucidate the genetic defect in four previously reported related Brahman calves with severe myasthenic weakness, we determined the genomic structure of the…”
Get full text

Familial meningioma is not allelic to neurofibromatosis 2 by PULST, S.-M, ROULEAU, G. A, MARINEAU, C, FAIN, P, SIEB, J. P

“…Meningiomas frequently lose parts of chromosome 22 (CHR 22), suggesting that a meningioma tumor-suppressor gene is located on CHR 22. Since meningiomas are…”
Get full text

Congenital myasthenic syndrome of Brahman cattle in South Africa by Thompson, P. N., Steinlein, O. K., Harper, C. K., Kraner, S., Sieb, J. B., Guthrie, A. J.

“…A congenital myasthenic syndrome in Brahman cattle is caused by a homozygous 20 base pair deletion (470del20) in the gene coding for the epsilon subunit of the…”
Get full text

Severe congenital myasthenic syndrome due to homozygosity of the 1293insG ε-acetylcholine receptor subunit mutation by Sieb, J. P., Kraner, S., Schrank, B., Reitter, B., Goebel, T. H. H., Tzartos, S. J., Steinlein, O. K.

“…Recently, a congenital myasthenic syndrome (CMS) with end‐plate acetylcholine receptor (AChR) deficiency due to missense mutations in the genes for the AChR…”
Get full text

Fluoroquinolone antibiotics block neuromuscular transmission by SIEB, J. P

Get full text

Congenital myasthenic syndrome due to heteroallelic nonsense/missense mutations in the acetylcholine receptor epsilon subunit gene by Kraner, S., Burgunder, J.-M., Rösler, K. M., Steinlein, O. K., Sieb, J. P.

Get full text

Immunohistochemical detection of complement factors: a reliable method for the diagnosis of myasthenia gravis by Zander, T, Schwab, S, Laufenberg, I, Sieb, J P

“…A 57-year-old woman suffered from generalized muscular weakness without diplopia or dysphagia for about 2 years. An abnormal decremental response on low…”
Get full text