Search Results - "Sidor, Michelle M."
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Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania
Published in The Journal of neuroscience (01-12-2010)“…Polymorphisms in circadian genes such as CLOCK convey risk for bipolar disorder. While studies have begun to elucidate the molecular mechanism whereby…”
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Psychiatry’s age of enlightenment: optogenetics and the discovery of novel targets for the treatment of psychiatric disorders
Published in Journal of psychiatry & neuroscience (2012)“…The identification of light-sensitive ion channels, called rho - dopsins, in microbial organisms has proven to be the quintessential discovery providing the…”
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3
Antidepressants for the Acute Treatment of Bipolar Depression: A Systematic Review and Meta-Analysis
Published in The journal of clinical psychiatry (01-02-2011)“…The role of antidepressants in the acute treatment of bipolar depression remains a contentious issue. A previous meta-analysis of randomized controlled trials…”
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4
The effect of early life immune challenge on adult forced swim test performance and hippocampal neurogenesis
Published in Journal of neuroimmunology (15-05-2021)“…Many psychiatric diseases can be considered neurodevelopmental in nature and accumulating evidence links immune system dysfunction to disease etiology. Yet, it…”
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5
Proliferating brain cells are a target of neurotoxic CSF in systemic autoimmune disease
Published in Journal of neuroimmunology (01-12-2005)“…Brain atrophy, neurologic and psychiatric (NP) manifestations are common complications in the systemic autoimmune disease, lupus erythematosus (SLE). Here we…”
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6
Antimanic Efficacy of a Novel Kv3 Potassium Channel Modulator
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2018)“…Kv3.1 and Kv3.2 voltage-gated potassium channels are expressed on parvalbumin-positive GABAergic interneurons in corticolimbic brain regions and contribute to…”
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7
Specific Role of VTA Dopamine Neuronal Firing Rates and Morphology in the Reversal of Anxiety-Related, but not Depression-Related Behavior in the Clock Delta 19 Mouse Model of Mania
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2011)“…Lithium has been used extensively for mood stabilization, and it is particularly efficacious in the treatment of bipolar mania. Like other drugs used in the…”
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8
An Update on Antidepressant Use in Bipolar Depression
Published in Current psychiatry reports (01-12-2012)“…The effective treatment of depression in people with bipolar disorder remains a clinical challenge. The role of antidepressant medication in treating bipolar…”
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9
Specific Role of VTA Dopamine Neuronal Firing Rates and Morphology in the Reversal of Anxiety-Related, but not Depression-Related Behavior in the ClockΔ19 Mouse Model of Mania
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2011)“…Lithium has been used extensively for mood stabilization, and it is particularly efficacious in the treatment of bipolar mania. Like other drugs used in the…”
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10
Timing matters: using optogenetics to chronically manipulate neural circuitry and rhythms
Published in Frontiers in behavioral neuroscience (14-02-2014)“…The ability to probe defined neural circuits with both the spatial and temporal resolution imparted by optogenetics has transformed the field of neuroscience…”
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11
Circadian clocks, brain function, and development
Published in Annals of the New York Academy of Sciences (01-12-2013)“…Circadian clocks are temporal interfaces that organize biological systems and behavior to dynamic external environments. Components of the molecular clock are…”
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12
Validation of an automated system for measuring anxiety-related behaviours in the elevated plus maze
Published in Journal of neuroscience methods (30-04-2010)“…The elevated plus maze (EPM) is one of the most widely used and established tests to assess anxiety-related behaviours and has been validated for use in both…”
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13
In vivo optogenetic stimulation of the rodent central nervous system
Published in Journal of visualized experiments (15-01-2015)“…The ability to probe defined neural circuits in awake, freely-moving animals with cell-type specificity, spatial precision, and high temporal resolution has…”
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14
Tuning the Brain-Gut Axis in Health and Disease
Published in Current stem cell reports (01-03-2015)“…Recent breakthroughs in gut microbiome-derived technologies and therapies, coupled with the lack of invasiveness associated with them, provide attractive…”
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15
Elevated immunoglobulin levels in the cerebrospinal fluid from lupus-prone mice
Published in Journal of neuroimmunology (01-08-2005)“…The systemic autoimmune disease lupus erythematosus (SLE) is frequently accompanied by neuropsychiatric manifestations and brain lesions of unknown etiology…”
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16
Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice
Published in Molecular psychiatry (01-11-2015)“…Disruptions in circadian rhythms and dopaminergic activity are involved in the pathophysiology of bipolar disorder, though their interaction remains unclear…”
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17
Drs Sidor and MacQueen Reply
Published in The journal of clinical psychiatry (15-03-2011)Get full text
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18
Timing matters: Using optogenetics to chronically manipulate neural circuits and rhythms
Published in Frontiers in behavioral neuroscience (01-02-2014)“…The ability to probe defined neural circuits with both the spatial and temporal resolution imparted by optogenetics has transformed the field of neuroscience…”
Get full text
Journal Article -
19
In vivo Optogenetic Stimulation of the Rodent Central Nervous System
Published in Journal of visualized experiments (15-01-2015)Get full text
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20
Specific Role of VTA Dopamine Neuronal Firing Rates and Morphology in the Reversal of Anxiety-Related, but not Depression-Related Behavior in the Clock[Delta]19 Mouse Model of Mania
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2011)“…Lithium has been used extensively for mood stabilization, and it is particularly efficacious in the treatment of bipolar mania. Like other drugs used in the…”
Get full text
Journal Article