Search Results - "Sidibeh, Cherno O."
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FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes
Published in Endocrine (01-10-2018)“…Purpose Here, we explore the involvement of FKBP51 in glucocorticoid-induced insulin resistance (IR) in human subcutaneous adipose tissue (SAT), including its…”
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Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors
Published in Metabolism, clinical and experimental (01-12-2016)“…Elevated levels of circulating non-esterified fatty acids (NEFA) mediate many adverse metabolic effects. In this work we aim to determine the impact of type 2…”
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FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance
Published in Metabolism, clinical and experimental (01-09-2014)“…Abstract Objective To study effects of dexamethasone on gene expression in human adipose tissue aiming to identify potential novel mechanisms for…”
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Role of cannabinoid receptor 1 in human adipose tissue for lipolysis regulation and insulin resistance
Published in Endocrine (01-03-2017)“…We recently showed that the peripheral cannabinoid receptor type 1 ( CNR1 ) gene is upregulated by the synthetic glucocorticoid dexamethasone. CNR1 is highly…”
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Lipocalin 2 produces insulin resistance and can be upregulated by glucocorticoids in human adipose tissue
Published in Molecular and cellular endocrinology (15-05-2016)“…The adipokine lipocalin 2 is linked to obesity and metabolic disorders. However, its role in human adipose tissue glucose and lipid metabolism is not explored…”
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FKBP51 ablation using CRISPR/Cas-9 impairs adipocyte differentiation
Published in Diabetologia (2018)Get full text
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Role of lipocalin 2 in human adipose tissue metabolism and glucocorticoid-induced insulin resistance
Published in Diabetologia (2015)Get full text
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Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important
Published in Metabolism, clinical and experimental (2016)“…Abstract Background Elevated levels of circulating non-esterified fatty acids (NEFA) mediate many adverse metabolic effects. In this work we aim to determine…”
Get full text
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FKBP5 gene polymorphisms and expression in human adipose tissue are associated with insulin resistance and type 2 diabetes
Published in Diabetologia (2014)Get full text
Journal Article