Search Results - "Sidhaye, Jaydeep"
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Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease
Published in Cell death and differentiation (01-01-2021)“…Understanding etiology of human neurological and psychiatric diseases is challenging. Genomic changes, protracted development, and histological features unique…”
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Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis
Published in eLife (04-04-2017)“…Organ formation is a multi-scale event that involves changes at the intracellular, cellular and tissue level. Organogenesis often starts with the formation of…”
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Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids
Published in eLife (29-03-2023)“…During development of the human cerebral cortex, multipotent neural progenitors generate excitatory neurons and glial cells. Investigations of the…”
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Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis
Published in PLoS genetics (01-09-2014)“…The epidermis is a stratified epithelium, which forms a barrier to maintain the internal milieu in metazoans. Being the outermost tissue, growth of the…”
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5
The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease
Published in Mechanisms of development (01-11-2016)“…Microvillus inclusion disease (MVID) is a life-threatening enteropathy characterised by malabsorption and incapacitating fluid loss due to chronic diarrhoea…”
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6
Collective cell migration during optic cup formation features changing cell-matrix interactions linked to matrix topology
Published in Current biology (21-11-2022)“…Cell migration is crucial for organismal development and shapes organisms in health and disease. Although a lot of research has revealed the role of…”
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Interkinetic Nuclear Migration Is Centrosome Independent and Ensures Apical Cell Division to Maintain Tissue Integrity
Published in Developmental cell (26-01-2015)“…Pseudostratified epithelia are widespread during animal development and feature elongated cells whose nuclei adopt various positions along the apicobasal cell…”
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Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous extracellular matrix
Published in The EMBO journal (15-11-2023)“…The establishment and maintenance of apical-basal polarity is a fundamental step in brain development, instructing the organization of neural progenitor cells…”
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ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum
Published in Cell stem cell (06-06-2024)“…Mutations in ARID1B, a member of the mSWI/SNF complex, cause severe neurodevelopmental phenotypes with elusive mechanisms in humans. The most common structural…”
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Using Light Sheet Fluorescence Microscopy to Image Zebrafish Eye Development
Published in Journal of visualized experiments (10-04-2016)“…Light sheet fluorescence microscopy (LSFM) is gaining more and more popularity as a method to image embryonic development. The main advantages of LSFM compared…”
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11
Using Light Sheet Fluorescence Microscopy to Image Zebrafish Eye Development
Published in Journal of visualized experiments (10-04-2016)Get full text
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12
Myosin Vb Mediated Plasma Membrane Homeostasis Regulates Peridermal Cell Size and Maintains Tissue Homeostasis in the Zebrafish Epidermis: e1004614
Published in PLoS genetics (01-09-2014)“…The epidermis is a stratified epithelium, which forms a barrier to maintain the internal milieu in metazoans. Being the outermost tissue, growth of the…”
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