Search Results - "Sidharthan, Sreetha"
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Utility of Hepatitis C Viral Load Monitoring on Direct-Acting Antiviral Therapy
Published in Clinical infectious diseases (15-06-2015)“…Background. Hepatitis C virus (HCV) RNA loads serve as predictors of treatment response during interferon-based therapy. We evaluated the predictive ability of…”
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Ledipasvir and sofosbuvir for hepatitis C genotype 4: a proof-of-concept, single-centre, open-label phase 2a cohort study
Published in The Lancet infectious diseases (01-09-2015)“…Summary Background Worldwide, although predominantly in low-income countries in the Middle East and Africa, up to 13% of hepatitis C virus (HCV) infections are…”
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3
Mechanisms of alcohol-induced hepatocellular carcinoma
Published in Hepatology international (01-09-2014)“…Chronic alcohol abuse is a major risk factor for hepatocellular carcinoma (HCC), the third leading cause of cancer deaths worldwide. Alcohol can also function…”
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Four-Week Direct-Acting Antiviral Regimens in Noncirrhotic Patients With Hepatitis C Virus Genotype 1 Infection: An Open-Label, Nonrandomized Trial
Published in Annals of internal medicine (15-12-2015)“…Treatment of chronic hepatitis C virus (HCV) infection with direct-acting antivirals (DAAs) for 6 weeks achieves sustained virologic response (SVR) rates of…”
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Interferon-Free Treatment of Hepatitis C Virus in HIV/Hepatitis C Virus-Coinfected Subjects Results in Increased Serum Low-Density Lipoprotein Concentration
Published in AIDS research and human retroviruses (01-05-2016)“…Chronic hepatitis C virus (HCV) infection is associated with lower serum concentration of low-density lipoprotein (LDL-C), the primary cholesterol metabolite…”
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High adherence to all-oral directly acting antiviral HCV therapy among an inner-city patient population in a phase 2a study
Published in Hepatology international (01-03-2016)“…Background As treatment for chronic hepatitis C (HCV) virus has evolved to all-oral, interferon-free directly acting antiviral (DAA) therapy, the impact of…”
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Patterns of Articular Cartilage Thickness in Pediatric and Adolescent Knees: A Magnetic Resonance Imaging–Based Study
Published in Arthroscopy, Sports Medicine, and Rehabilitation (01-04-2021)“…To establish normative values for articular cartilage thickness in pediatric and adolescent knees using magnetic resonance imaging (MRI) and investigate for…”
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Bifocal Patellar Tendon Avulsion Fractures in Children and Adolescents: Diagnosis and Treatment Considerations for a Unique Injury Pattern
Published in Arthroscopy, Sports Medicine, and Rehabilitation (01-02-2021)“…To highlight important diagnostic and treatment considerations in patients who present with bifocal patellar tendon avulsion fractures from the tibial tubercle…”
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Editorial Commentary: A Posterior Tibial Tubercle Relative to the Trochlear Groove Is Associated With Increased Risk of Patellofemoral Arthritis: The Sagittal Tibial Tubercle–Trochlear Groove Distance
Published in Arthroscopy (01-06-2023)“…Arthritis of the patellofemoral compartment affects up to 24% of women and 11% of men over the age of 55 years who have symptomatic osteoarthritis of the knee…”
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Increased Posterior Tibial Slope in Patients With Osgood-Schlatter Disease: A New Association
Published in The American journal of sports medicine (01-03-2020)“…Background: Osgood-Schlatter disease (OSD) is a traction apophysitis of the tibial tubercle caused by repetitive strain and chronic avulsion from the patellar…”
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Reply to Harrington et al
Published in Clinical infectious diseases (15-08-2015)Get full text
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Virologic Response Following Combined Ledipasvir and Sofosbuvir Administration in Patients With HCV Genotype 1 and HIV Co-infection
Published in JAMA : the journal of the American Medical Association (24-03-2015)“…IMPORTANCE: There is an unmet need for interferon- and ribavirin-free treatment for chronic hepatitis C virus (HCV) infection in patients co-infected with…”
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Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study
Published in The Lancet (British edition) (21-03-2015)“…Summary Background Direct-acting antiviral drugs have a high cure rate and favourable tolerability for patients with hepatitis C virus (HCV). Shorter courses…”
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Pediatric Management of Recurrent Patellar Instability
Published in Sports medicine and arthroscopy review (01-12-2019)“…Patellofemoral instability is a common orthopedic condition in children and adolescents, with recurrent instability often requiring surgical intervention. Age,…”
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Normal Glenoid Ossification in Pediatric and Adolescent Shoulders Mimics Bankart Lesions: A Magnetic Resonance Imaging–Based Study
Published in Arthroscopy (01-02-2020)“…The purpose of this descriptive study was to define patterns of ossification and fusion of growth centers around the pediatric and adolescent glenoid as a…”
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Successful Retreatment of Chronic HCV Genotype-1 Infection With Ledipasvir and Sofosbuvir After Initial Short Course Therapy With Direct-Acting Antiviral Regimens
Published in Clinical infectious diseases (01-02-2016)“…Background. The optimal retreatment strategy for chronic hepatitis C virus (HCV) patients who fail directly-acting antiviral agent (DAA)-based treatment is…”
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Bariatric Surgery Prior to Total Hip Arthroplasty Is Cost-Effective in Morbidly Obese Patients
Published in The Journal of arthroplasty (01-07-2020)“…The cost-effectiveness of bariatric surgery to achieve weight loss prior to total hip arthroplasty (THA), and decrease the complications and costs associated…”
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Pediatric Orthopaedic Studies Published Open Access are Associated with Increased Citation Rates
Published in Journal of the Pediatric Orthopaedic Society of North America (01-11-2024)“…Open access (OA) articles are freely accessible online, either on the publisher/journal website or in a repository, a publicly available, free-of-charge online…”
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Moderate Sustained Virologic Response Rates With 6-Week Combination Directly Acting Anti–Hepatitis C Virus Therapy in Patients With Advanced Liver Disease
Published in Clinical infectious diseases (15-02-2016)“…Background. Treatment of genotype 1 hepatitis C virus (HCV) infection with combination directly acting antivirals (DAA) for 8–24 weeks is associated with high…”
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IS OSGOOD-SCHLATTER DISEASE TRULY A BENIGN KNEE CONDITION? A PILOT STUDY DEMONSTRATING INCREASED POSTERIOR TIBIAL SLOPE
Published in Orthopaedic journal of sports medicine (01-04-2020)“…Background: Osgood-Schlatter disease (OSD) is a traction apophysitis caused by repetitive strain and chronic avulsion of the secondary ossification center of…”
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