Search Results - "Sideris, P"
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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Published in Nature (London) (20-08-2015)“…Protein aggregates and damaged organelles are tagged with ubiquitin chains to trigger selective autophagy. To initiate mitophagy, the ubiquitin kinase PINK1…”
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2
Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1
Published in Molecular cell (07-03-2019)“…Mutations in PTEN-induced kinase 1 (PINK1) can cause recessive early-onset Parkinson’s disease (PD). Import arrest results in PINK1 kinase activation…”
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3
Shear-Enhanced Gradient Inelastic Force-Based Frame Element Formulation for Analysis of Shear-Critical Reinforced Concrete Members
Published in Journal of structural engineering (New York, N.Y.) (01-11-2024)“…AbstractA large number of structures in the United States and worldwide include nonductile reinforced concrete (RC) frames with columns and beams that are…”
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4
Intimate Relations-Mitochondria and Ageing
Published in International journal of molecular sciences (14-10-2020)“…Mitochondrial dysfunction is associated with ageing, but the detailed causal relationship between the two is still unclear. We review the major…”
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Experimental characterization and constitutive modeling of polyurethanes for structural applications, accounting for damage, hysteresis, loading rate and long term effects
Published in Engineering structures (01-11-2019)“…Polymers are highly customizable materials that present high potential for applications in the development of damage-resistant structural systems. Out of the…”
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Resilient Bridge Rocking Columns with Polyurethane Damage-Resistant End Segments and Replaceable Energy-Dissipating Links
Published in Journal of bridge engineering (01-10-2017)“…AbstractThis paper introduces a novel low-damage bridge column design for accelerated bridge construction (ABC) in seismic areas. The proposed design…”
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7
Experimental Performance Assessment of Nearly Full-Scale Reinforced Concrete Columns with Partially Debonded Longitudinal Reinforcement
Published in Journal of structural engineering (New York, N.Y.) (01-04-2017)“…AbstractThis paper presents an experimental study investigating the effect of partial debonding of longitudinal reinforcement at the location of the plastic…”
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8
Erv1 Mediates the Mia40-dependent Protein Import Pathway and Provides a Functional Link to the Respiratory Chain by Shuttling Electrons to Cytochrome c
Published in Journal of molecular biology (11-11-2005)“…Unlike matrix-targeted or inner membrane proteins, those that are targeted to the mitochondrial intermembrane space (IMS) do not require ATP or the inner…”
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9
Nonlocal Hardening-Damage Beam Model and Its Application to a Force-Based Element Formulation
Published in Journal of engineering mechanics (01-10-2019)“…AbstractThis paper introduces a novel nonlocal hardening-damage model for beams and integrates it within a flexibility-based frame element formulation. The…”
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10
PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis
Published in Cell reports (Cambridge) (01-10-2019)“…PINK1 and Parkin are established mediators of mitophagy, the selective removal of damaged mitochondria by autophagy. PINK1 and Parkin have been proposed to act…”
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Oxidative protein folding in the mitochondrial intermembrane space
Published in Antioxidants & redox signaling (15-10-2010)“…Disulfide bond formation is a crucial step for oxidative folding and necessary for the acquisition of a protein's native conformation. Introduction of…”
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12
Role of Membrane Association and Atg14-Dependent Phosphorylation in Beclin-1-Mediated Autophagy
Published in Molecular and Cellular Biology (01-09-2013)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding
Published in The Journal of cell biology (28-12-2009)“…Mia40 imports Cys-containing proteins into the mitochondrial intermembrane space (IMS) by ensuring their Cys-dependent oxidative folding. In this study, we…”
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14
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
Published in Neuron (Cambridge, Mass.) (15-07-2015)“…Parkinson’s disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic neurons in the substantia nigra. PARK2 mutations cause early-onset…”
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15
Balanced Ero1 activation and inactivation establishes ER redox homeostasis
Published in The Journal of cell biology (19-03-2012)“…The endoplasmic reticulum (ER) provides an environment optimized for oxidative protein folding through the action of Ero1p, which generates disulfide bonds,…”
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16
RF Performance of Devices Processed in Low-Temperature Sequential Integration
Published in IEEE transactions on electron devices (01-07-2021)“…RF performance and intertier coupling of CMOS processed in 3-D sequential integration are investigated. pMOS transistor fabricated with a 500 °C thermal budget…”
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Risk-Based Assessment of Seismic Repair Costs for Reinforced Concrete Bridges Considering Competing Repair Strategies
Published in Journal of bridge engineering (01-11-2019)“…AbstractThis paper outlines a procedure to support the selection of repair strategies for damaged structures after an earthquake. Under strong shaking, modern…”
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18
Translocation of mitochondrial inner-membrane proteins: conformation matters
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-05-2006)“…Most of the mitochondrial inner-membrane proteins are generated without a presequence and their targeting depends on inadequately defined internal segments…”
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19
Wildfire impacts on hillslope sediment and phosphorus yields
Published in Journal of soils and sediments (01-05-2010)“…Purpose The impact of wildfire on (a) slope hydrological processes, (b) soil erodibility, and (c) post-fire hillslope sediment and phosphorus (P; dissolved and…”
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20
Modulation of mitochondrial dysfunction for treatment of disease
Published in Bioorganic & medicinal chemistry letters (01-06-2019)“…[Display omitted] Mitochondrial dysfunction is a causative and/or exacerbating feature of many pathologies. We discuss below approaches to modulate…”
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