Search Results - "Siddiqui, Sarwar"
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Tools to study and target the Siglec–sialic acid axis in cancer
Published in The FEBS journal (01-11-2021)“…The Siglec–Sia axis is an important modulator of cancer immune response. There are various methods and tools used for studying and targeting this axis. The…”
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Differential expression of ST6GALNAC1 and ST6GALNAC2 and their clinical relevance to colorectal cancer progression
Published in PloS one (30-09-2024)“…Colorectal cancer (CRC) has become a significant global health concern and ranks among the leading causes of morbidity and mortality worldwide. Due to its…”
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3
Vitamin C therapy in septic shock
Published in Critical care (London, England) (30-03-2022)“…[...]neuronal cells and activated leukocytes actively concentrate vitamin C via sodium-dependent SVCT2 transporter, which protects them from reactive oxygen…”
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Can normal breath sounds in mechanically ventilated patients be termed vesicular?
Published in Critical care (London, England) (30-09-2023)“…To this end, we review the characteristics of vesicular breath sounds and elucidate the differences in flow patterns in mechanical ventilated patients…”
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Re: Thromboelastograph: A prognostic marker in sepsis with organ dysfunction without overt bleeding
Published in Journal of critical care (01-04-2022)Get full text
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Pattern of neurological diseases in adult outpatient neurology clinics in tertiary care hospital
Published in BMC research notes (02-11-2017)“…The burden of neurological diseases in developing countries is rising although little is known about the epidemiology and clinical pattern of neurological…”
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Letter to the Editor: "Impact of hypoalbuminemia on mortality in critically ill patients requiring continuous renal replacement therapy"
Published in Journal of critical care (01-06-2022)“…Continuous venovenous hemofiltration (CVVH): CVVH is a hemofiltration-based CRRT modality with ultrafiltration mediated higher fluid and protein losses as…”
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Novel Siglec-15-Sia axis inhibitor leads to colorectal cancer cell death by targeting miR-6715b-3p and oncogenes
Published in Frontiers in immunology (06-10-2023)“…Siglecs are well known immunotherapeutic targets in cancer. Current checkpoint inhibitors have exhibited limited efficacy, prompting a need for novel…”
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Emergence of blaNDM-1 and blaVIM producing Gram-negative bacilli in ventilator-associated pneumonia at AMR Surveillance Regional Reference Laboratory in India
Published in PloS one (08-09-2021)“…Ventilator-associated pneumonia (VAP) may be a life threatening nosocomial infection encountered in intensive care units. Currently the emergence of…”
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Acute Onset of Quadriplegia Secondary to Hypoparathyroidism: Mimicker of AMAN Variant of GBS
Published in Journal of the College of Physicians and Surgeons--Pakistan (01-03-2018)“…Acute onset of quadriplegia is a rare phenomenon seen with hypocalcemia due to hypoparathyroidism. We describe a 33-year gentleman who presented with weakness…”
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Disaster Classification: An Unmet Need for a Pragmatic Medical Classification After COVID-19
Published in Disaster medicine and public health preparedness (10-05-2023)Get more information
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12
Depression and the Use of Selective Serotonin Reuptake Inhibitors in Patients with Acute Intracerebral Hemorrhage
Published in Curēus (Palo Alto, CA) (23-10-2019)“…Introduction Depression is a common psychiatric complication associated with stroke. However, while most studies focus on post-stroke depression (PSD)…”
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Siglecs in Brain Function and Neurological Disorders
Published in Cells (Basel, Switzerland) (22-09-2019)“…Siglecs (Sialic acid-binding immunoglobulin-type lectins) are a I-type lectin that typically binds sialic acid. Siglecs are predominantly expressed in immune…”
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14
Natural compound catechol induces DNA damage, apoptosis, and G1 cell cycle arrest in breast cancer cells
Published in Phytotherapy research (01-04-2021)“…Targeting cell cycle and inducing DNA damage by activating cell death pathways are considered as effective therapeutic strategy for combating breast cancer…”
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15
Editorial: The use of plant metabolites to ameliorate sequelae of chemotherapy
Published in Frontiers in pharmacology (07-11-2023)Get full text
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16
The evolution of clot strength in critically ill COVID-19 patients: a prospective observational thromboelastography study
Published in Thrombosis journal (14-02-2022)“…The authors have done commendable work in exploring the utility of a comprehensive viscoelastic test for assessment of the coagulation cascade in Coronavirus…”
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Plant Flavonoids on Oxidative Stress-Mediated Kidney Inflammation
Published in Biology (Basel, Switzerland) (26-11-2022)“…The kidney is susceptible to reactive oxygen species-mediated cellular injury resulting in glomerulosclerosis, tubulointerstitial fibrosis, tubular cell…”
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Internal water pressure development in saturated concrete cylinder subjected to coefficient of thermal expansion tests: Poroelastic model
Published in Construction & building materials (01-06-2016)“…•Quantify the internal water pressure development in a saturated CTE concrete sample.•Numerical model is in good agreement with the experimental…”
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Clinical pharmacokinetics of 3-h extended infusion of meropenem in adult patients with severe sepsis and septic shock: implications for empirical therapy against Gram-negative bacteria
Published in Annals of intensive care (10-01-2020)“…Background Optimal anti-bacterial activity of meropenem requires maintenance of its plasma concentration (Cp) above the minimum inhibitory concentration (MIC)…”
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Monitoring Macro- and Microcirculation in the Critically Ill: A Narrative Review
Published in Avicenna journal of medicine (01-07-2023)“…Abstract Circulatory shock is a common and important diagnosis in the critical care environment. Hemodynamic monitoring is quintessential in the management of…”
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