Search Results - "Siddiqui, Rafat A."
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Nutritional Composition and Bioactive Components in Quinoa ( Chenopodium quinoa Willd.) Greens: A Review
Published in Nutrients (27-01-2022)“…Quinoa ( Willd.) is a nutrient-rich grain native to South America and eaten worldwide as a healthy food, sometimes even referred to as a "superfood". Like…”
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Nutraceuticals and Nutrition Supplements: Challenges and Opportunities
Published in Nutrients (29-05-2020)“…The term "nutraceuticals" is derived from "nutrition" and "pharmaceuticals" and is used fornutrition products that are also used as medicine [1] [...]…”
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3
Antidepressant Sertraline Hydrochloride Inhibits the Growth of HER2+ AU565 Breast Cancer Cell Line through Induction of Apoptosis and Cell Cycle Arrest
Published in Anti-cancer agents in medicinal chemistry (01-01-2024)“…Drug repurposing in oncology promises benefits to many patients through its ability to provide novel, and fast-tracked treatments. Previous studies have…”
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4
Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification
Published in Clinical & experimental metastasis (01-12-2011)“…We previously described a lipid-accumulating phenotype of estrogen receptor negative (ER − ) breast cancer cells exemplified by the MDA-MB-231 and MDA-MB-436…”
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5
Immature ginger reduces triglyceride accumulation by downregulating Acyl CoA carboxylase and phosphoenolpyruvate carboxykinase-1 genes in 3T3-L1 adipocytes
Published in Food & nutrition research (02-03-2023)“…Obesity is the underlying risk factor for major metabolism complications, including non-alcoholic-fatty liver disease, atherosclerosis, and cardiovascular…”
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Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells
Published in Journal of lipid research (01-12-2010)“…Saturated fatty acids (SFAs), significant components of both enteral/parenteral nutritional formulations (including diet), are linked to cardiovascular disease…”
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Anticancer properties of oxidation products of docosahexaenoic acid
Published in Chemistry and physics of lipids (01-05-2008)“…Docosahexaenoic acid (DHA) is the longest, most unsaturated, and hence, most oxidizable fatty acid commonly found in nature. The mechanisms behind DHA's many…”
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Omega-3 Polyunsaturated Fatty Acids Down-Modulate CXCR4 Expression and Function in MDA-MB-231 Breast Cancer Cells
Published in Molecular cancer research (01-07-2009)“…Metastasis is the leading cause of death from breast cancer. A major factor of metastasis is the migration of cancerous cells to other tissues by way of…”
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Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells
Published in Nutrients (15-05-2019)“…Preventing muscle wasting in certain chronic diseases including cancer is an ongoing challenge. Studies have shown that polyphenols derived from fruits and…”
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10
Engineering of fluorescent or photoactive Trojan probes for detection and eradication of β-Amyloids
Published in Drug delivery (01-01-2020)“…Trojan horse technology institutes a potentially promising strategy to bring together a diagnostic or cell-based drug design and a delivery platform. It…”
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Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth
Published in Clinical nutrition (Edinburgh, Scotland) (01-08-2010)“…Summary Background & aims Saturated fatty acids (SFAs), significant components of enteral and parenteral formulations, have been linked to cardiovascular…”
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A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone
Published in BMC cancer (21-04-2011)“…Breast cancer is a collection of diseases in which molecular phenotypes can act as both indicators and mediators of therapeutic strategy. Therefore, candidate…”
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13
Modulation of enzymatic activities by n-3 polyunsaturated fatty acids to support cardiovascular health
Published in The Journal of nutritional biochemistry (01-07-2008)“…Epidemiological evidence from Greenland Eskimos and Japanese fishing villages suggests that eating fish oil and marine animals can prevent coronary heart…”
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14
Trans Fatty Acids: Induction of a Pro-inflammatory Phenotype in Endothelial Cells
Published in Lipids (01-07-2012)“…Epidemiological data have shown an association of the intake of industrial produced trans fatty acids (TFA) and sudden cardiac death. The present study…”
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Comparative study of the modulation of fructose/sucrose-induced hepatic steatosis by mixed lipid formulations varying in unsaturated fatty acid content
Published in Nutrition & metabolism (14-11-2015)“…Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in developed countries. NAFLD encompasses a spectrum of diseases,…”
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16
Steroidal compounds in commercial parenteral lipid emulsions
Published in Nutrients (01-08-2012)“…Parenteral nutrition lipid emulsions made from various plant oils contain steroidal compounds, called phytosterols. During parenteral administration of lipid…”
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Oleic and Docosahexaenoic Acid Differentially Phase Separate from Lipid Raft Molecules: A Comparative NMR, DSC, AFM, and Detergent Extraction Study
Published in Biophysical journal (01-09-2004)“…We have previously suggested that the ω-3 polyunsaturated fatty acid, docosahexaenoic acid (DHA) may in part function by enhancing membrane lipid phase…”
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18
Modulation of endothelial cell integrity and inflammatory activation by commercial lipid emulsions
Published in Lipids in health and disease (18-02-2015)“…Thrombosis and immune dysfunction are two important complications that result from the administration of parenteral nutrition. Endothelial cells within the…”
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n-3 Fatty acids prevent whereas trans-fatty acids induce vascular inflammation and sudden cardiac death
Published in British journal of nutrition (28-12-2009)“…n-3 PUFA have well-recognised cardio-beneficial effects. In contrast, premature coronary deaths are associated with consumption of high levels of trans-fatty…”
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Anticancer properties of propofol-docosahexaenoate and propofol-eicosapentaenoate on breast cancer cells
Published in Breast cancer research : BCR (01-01-2005)“…Epidemiological evidence strongly links fish oil, which is rich in docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), with low incidences of several…”
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