Search Results - "Siddiqui, Jawed"

Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement by Siddiqui, Jawed A, Partridge, Nicola C

“…Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial…”
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Targeting autophagy and lipid metabolism in cancer stem cells by Chakravarti, Bandana, Akhtar Siddiqui, Jawed, Anthony Sinha, Rohit, Raza, Sana

“…[Display omitted] Cancer stem cells (CSCs) are a subset of cancer cells with self-renewal ability and tumor initiating properties. Unlike the other non-stem…”
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Advances in cancer cachexia: Intersection between affected organs, mediators, and pharmacological interventions by Siddiqui, Jawed A., Pothuraju, Ramesh, Jain, Maneesh, Batra, Surinder K., Nasser, Mohd W.

“…Advanced cancer patients exhibit cachexia, a condition characterized by a significant reduction in the body weight predominantly from loss of skeletal muscle…”
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Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance by Pothuraju, Ramesh, Rachagani, Satyanarayana, Krishn, Shiv Ram, Chaudhary, Sanjib, Nimmakayala, Rama Krishna, Siddiqui, Jawed A, Ganguly, Koelina, Lakshmanan, Imayavaramban, Cox, Jesse L, Mallya, Kavita, Kaur, Sukhwinder, Batra, Surinder K

“…Differential expression of mucins has been associated with several cancers including colorectal cancer (CRC). In normal physiological conditions, secretory…”
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microRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy by Kanchan, Ranjana K, Siddiqui, Jawed A, Mahapatra, Sidharth, Batra, Surinder K, Nasser, Mohd W

“…Brain metastasis (BM) predominantly occurs in triple-negative (TN) and epidermal growth factor 2 (HER2)-positive breast cancer (BC) patients, and currently,…”
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Diverse landscape of genetically engineered mouse models: Genomic and molecular insights into prostate cancer by Kaushal, Jyoti B., Takkar, Simran, Batra, Surinder K., Siddiqui, Jawed A.

“…Prostate cancer (PCa) is a significant health concern for men worldwide and is particularly prevalent in the United States. It is a complex disease presenting…”
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Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells by Vengoji, Raghupathy, Macha, Muzafar A, Nimmakayala, Rama Krishna, Rachagani, Satyanarayana, Siddiqui, Jawed A, Mallya, Kavita, Gorantla, Santhi, Jain, Maneesh, Ponnusamy, Moorthy P, Batra, Surinder K, Shonka, Nicole

“…Glioblastoma (GBM) is an aggressive brain tumor with universal recurrence and poor prognosis. The recurrence is largely driven by chemoradiation resistant…”
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Editorial: Bone metastasis in the milieu of osteoimmunology by Sharma, Gunjan, Ponzetti, Marco, Siddiqui, Jawed A.

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Liquid biopsies to occult brain metastasis by Rehman, Asad Ur, Khan, Parvez, Maurya, Shailendra Kumar, Siddiqui, Jawed A, Santamaria-Barria, Juan A, Batra, Surinder K, Nasser, Mohd Wasim

“…Brain metastasis (BrM) is a major problem associated with cancer-related mortality, and currently, no specific biomarkers are available in clinical settings…”
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A Systematic Review and Meta-Analysis of the Effects of Dietary Isoflavones on Female Hormone-Dependent Cancers for Benefit-Risk Evaluation by Chakravarti, Bandana, Rajput, Swati, Srivastava, Anubhav, Sharma, Lokendra Kumar, Sinha, Rohit Anthony, Chattopadhyay, Naibedya, Siddiqui, Jawed Akhtar

“…Female hormone-dependent cancers depend on estrogen for their growth. Numerous studies have explored the antitumor effect of dietary isoflavones on female…”
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Phytochemicals for breast cancer therapy: current status and future implications by Siddiqui, Jawed Akhtar, Singh, Aru, Chagtoo, Megha, Singh, Nidhi, Godbole, Madan Madhav, Chakravarti, Bandana

“…Breast cancer is one of the most common malignancies among women, representing nearly 30% of newly diagnosed cancers every year. Till date, various therapeutic…”
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Gum acacia dietary fiber: Significance in immunomodulation, inflammatory diseases, and cancer by Barkeer, Srikanth, Pothuraju, Ramesh, Malakar, Pushkar, Pimentel, Tatiana Colombo, Siddiqui, Jawed A., Nair, S. Asha

“…Gum arabic/acacia (GA), derived from Acacia trees, is a versatile natural product offering a broad spectrum of applications. Its rich content of soluble…”
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α-lipoic acid modulates prostate cancer cell growth and bone cell differentiation by Abdullah, K. M., Sharma, Gunjan, Takkar, Simran, Kaushal, Jyoti B., Pothuraju, Ramesh, Chakravarti, Bandana, Batra, Surinder K., Siddiqui, Jawed A.

“…Prostate cancer (PCa) progression leads to bone modulation in approximately 70% of affected men. A nutraceutical, namely, α-lipoic acid (α-LA), is known for…”
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Osteoblastic monocyte chemoattractant protein-1 (MCP-1) mediation of parathyroid hormone's anabolic actions in bone implicates TGF-β signaling by Siddiqui, Jawed A., Le Henaff, Carole, Johnson, Joshua, He, Zhiming, Rifkin, Daniel B., Partridge, Nicola C.

“…Parathyroid hormone (PTH) is necessary for the regulation of calcium homeostasis and PTH (1–34) was the first approved osteoanabolic therapy for osteoporosis…”
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Emerging therapeutic potential of graviola and its constituents in cancers by Qazi, Asif Khurshid, Siddiqui, Jawed A, Jahan, Rahat, Chaudhary, Sanjib, Walker, Larry A, Sayed, Zafar, Jones, Dwight T, Batra, Surinder K, Macha, Muzafar A

“…Abstract Cancer remains a leading cause of death in the USA and around the world. Although the current synthetic inhibitors used in targeted therapies have…”
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From orphan to oncogene: The role of GPR35 in cancer and immune modulation by Takkar, Simran, Sharma, Gunjan, Kaushal, Jyoti B., Abdullah, K.M., Batra, Surinder K., Siddiqui, Jawed A.

“…G protein-coupled receptors (GPCRs) are well-studied and the most traceable cell surface receptors for drug discovery. One of the intriguing members of this…”
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Sildenafil Potentiates the Therapeutic Efficacy of Docetaxel in Advanced Prostate Cancer by Stimulating NO-cGMP Signaling by Muniyan, Sakthivel, Rachagani, Satyanarayana, Parte, Seema, Halder, Sushanta, Seshacharyulu, Parthasarathy, Kshirsagar, Prakash, Siddiqui, Jawed A, Vengoji, Raghupathy, Rauth, Sanchita, Islam, Ridwan, Mallya, Kavita, Datta, Kaustubh, Xi, Lei, Das, Anindita, Teply, Benjamin A, Kukreja, Rakesh C, Batra, Surinder K

“…Docetaxel plays an indispensable role in the management of advanced prostate cancer. However, more than half of patients do not respond to docetaxel, and those…”
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Clofazimine inhibits small-cell lung cancer progression by modulating the kynurenine/aryl hydrocarbon receptor axis by Sharma, Gunjan, Abdullah, K.M., Qais, Faizan Abul, Khan, Parvez, Cox, Jesse L., Sarwar, Tarique, Nasser, Mohd Wasim, Batra, Surinder K., Siddiqui, Jawed A.

“…Small cell lung cancer (SCLC) is one of the highly metastatic malignancies that contributes to ∼15 % of all lung cancers. Most SCLC patients (50–60 %) develop…”
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FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis by Seshacharyulu, Parthasarathy, Rachagani, Satyanarayana, Muniyan, Sakthivel, Siddiqui, Jawed A., Cruz, Eric, Sharma, Sunandini, Krishnan, Ramakrishnan, Killips, Brigham J., Sheinin, Yuri, Lele, Subodh M., Smith, Lynette M., Talmon, Geoffrey A., Ponnusamy, Moorthy P., Datta, Kaustubh, Batra, Surinder K.

“…Farnesyl diphosphate synthase (FDPS), a mevalonate pathway enzyme, is highly expressed in several cancers, including prostate cancer (PCa). To date, the…”
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Dual blockade of EGFR and CDK4/6 delays head and neck squamous cell carcinoma progression by inducing metabolic rewiring by Chaudhary, Sanjib, Pothuraju, Ramesh, Rachagani, Satyanarayana, Siddiqui, Jawed A., Atri, Pranita, Mallya, Kavita, Nasser, Mohd W., Sayed, Zafar, Lyden, Elizabeth R., Smith, Lynette, Gupta, Siddhartha D., Ralhan, Ranju, Lakshmanan, Imayavaramban, Jones, Dwight T., Ganti, Apar Kishor, Macha, Muzafar A., Batra, Surinder K.

“…Despite preclinical success, monotherapies targeting EGFR or cyclin D1-CDK4/6 in Head and Neck squamous cell carcinoma (HNSCC) have shown a limited clinical…”
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