Comparison of Different Antibiotic Medications on Microorganisms: An Original Research

Comparison of Different Antibiotic Medications on Microorganisms: An Original Research

The onset and maintenance of disease can be significantly influenced by the colonization of the mouth cavity by pathogenic microorganisms or by an imbalance of the physiological microbiome. Hence, in the current study, various commonly used antibiotics have been tested for their antibacterial and an...

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Bibliographic Details
Published in:Journal of pharmacy & bioallied science Vol. 16; no. Suppl 1; pp. S223 - S226
Main Authors: Patil, Ruthika S, Onteru, Pradeep, Jena, Janmajay, Shashank, Chapala, Siddiqua, Humera, Parikh, Hiral A, Tiwari, Heena Dixit
Format: Journal Article
Language:English
Published: India Medknow Publications and Media Pvt. Ltd 01-02-2024
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer - Medknow
Wolters Kluwer Medknow Publications
Subjects:
Analysis
antibacterial
Antibacterial agents
Antibiotic resistance
Antibiotics
antifungal
Antifungal activity
Antifungal agents
Ceftriaxone
Drug resistance
E coli
Escherichia coli
Lactobacillus
Linezolid
Microbiomes
Microorganisms
oral microbiome
Original
Physiological aspects
resistance
oral microbiome
antifungal
Antibacterial
antibiotics
resistance
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Summary:The onset and maintenance of disease can be significantly influenced by the colonization of the mouth cavity by pathogenic microorganisms or by an imbalance of the physiological microbiome. Hence, in the current study, various commonly used antibiotics have been tested for their antibacterial and antifungal activity. The current research was performed as an study. The commonly used antibiotics Augmentin (CV), Ceftriaxone-Cephalosporin (CF), and Linezolid were tested for the microorganisms, lactobacillus, and . The "Radius of Zone of Inhibition (mm)- RZI" after 24 and 48 h were tested by the agar-well diffusion method. For , the antibiotics tested were CV (5 μl and 2.5 μl), CF (5 μl and 2.5 μl), and Linezolid (5 μl and 2.5 μl). The results showed that the radius of the zone of inhibition was consistent for each antibiotic concentration, with a range of 0.8-1.4 mm at both time points. For Lactobacillus, the antibiotics tested were CV (5 μl and 2.5 μl), CF (5 μl and 2.5 μl), and Linezolid (5 μl and 2.5 μl). The results showed that the radius of the zone of inhibition varied between antibiotics and concentrations, with a range of 0.5-1.8 mm at both time points. This study highlights antibiotics' antibacterial action against and Lactobacillus. The data imply that antibiotic efficacy varied by organism and drug concentration. These organisms' antibiotic resistance mechanisms and new antibiotic resistance methods need more study.
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content type line 23
ISSN:0976-4879
0975-7406
DOI:10.4103/jpbs.jpbs_471_23