Search Results - "Siddiqi, Suhaib M"

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  1. 1

    Virtual terminator nucleotides for next-generation DNA sequencing by Thompson, John F, Bowers, Jayson, Mitchell, Judith, Beer, Eric, Buzby, Philip R, Causey, Marie, Efcavitch, J William, Jarosz, Mirna, Krzymanska-Olejnik, Edyta, Kung, Li, Lipson, Doron, Lowman, Geoffrey M, Marappan, Subramanian, McInerney, Peter, Platt, Adam, Roy, Atanu, Siddiqi, Suhaib M, Steinmann, Kathleen

    Published in Nature methods (01-08-2009)
    “…We synthesized reversible terminators with tethered inhibitors for next-generation sequencing. These were efficiently incorporated with high fidelity while…”
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  2. 2

    Antiviral Enantiomeric Preference for 5'-Noraristeromycin by Siddiqi, Suhaib M, Chen, Xing, Schneller, Stewart W, Ikeda, Satoru, Snoeck, Robert, Andrei, Graciela, Balzarini, Jan, De Clercq, Erik

    Published in Journal of medicinal chemistry (01-02-1994)
    “…In order to determine if the potent antiviral properties of (+/-)-5'-noraristeromycin reside in one of its enantiomers, an analysis of each enantiomer has been…”
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  3. 3

    Capture compound mass spectrometry: a technology for the investigation of small molecule protein interactions by Köster, Hubert, Little, Daniel P, Luan, Peng, Muller, Rolf, Siddiqi, Suhaib M, Marappan, Subramanian, Yip, Ping

    Published in Assay and drug development technologies (01-06-2007)
    “…One of the major hurdles in the post-genomic era is to understand the function of genes and the interplay of many different cellular proteins. This is…”
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  4. 4

    Search for New Purine- and Ribose-Modified Adenosine Analogs as Selective Agonists and Antagonists at Adenosine Receptors by Siddiqi, Suhaib M, Jacobson, Kenneth A, Esker, John L, Olah, Mark E, Ji, Xiao-duo, Melman, Neli, Tiwari, Kamal N, Secrist, John A, Schneller, Stewart W

    Published in Journal of medicinal chemistry (01-03-1995)
    “…The binding affinities at rat A1, A2a, and A3 adenosine receptors of a wide range of derivatives of adenosine have been determined. Sites of modification…”
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  5. 5

    Structure-Activity Relationships of 9-Alkyladenine and Ribose-Modified Adenosine Derivatives at Rat A3 Adenosine Receptors by Jacobson, Kenneth A, Siddiqi, Suhaib M, Olah, Mark E, Ji, Xiao-duo, Melman, Neli, Bellamkonda, Kamala, Meshulam, Yacov, Stiles, Gary L, Kim, Hea O

    Published in Journal of medicinal chemistry (01-05-1995)
    “…9-Alkyladenine derivatives and ribose-modified N6-benzyladenosine derivatives were synthesized in an effort to identify selective ligands for the rat A3…”
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  6. 6

    3-Deaza- and 7-Deaza-5'-noraristeromycin and Their Antiviral Properties by Siddiqi, Suhaib M, Chen, Xing, Rao, Jagadishwar, Schneller, Stewart W, Ikeda, Satoru, Snoeck, Robert, Andrei, Graciela, Balzarini, Jan, De Clercq, Erik

    Published in Journal of medicinal chemistry (01-03-1995)
    “…An enantiospecific synthesis of 3-deaza-5'-noraristeromycin as its dihydrochloride ((-)-6) has been accomplished in six steps beginning with the reaction of…”
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  7. 7

    An Epimer of 5'-Noraristeromycin and Its Antiviral Properties by Siddiqi, Suhaib M, Chen, Xing, Schneller, Stewart W, Ikeda, Satoru, Snoeck, Robert, Andrei, Graciela, Balzarini, Jan, De Clercq, Erik

    Published in Journal of medicinal chemistry (01-04-1994)
    “…A derivative of 5'-noraristeromycin epimeric at the 5'-nor center ((-)-3) has been prepared enantiospecifically in three steps from…”
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  8. 8

    Tetrahydrobenzothiophenone Derivatives as a Novel Class of Adenosine Receptor Antagonists by van Rhee, A. Michiel, Siddiqi, Suhaib M, Melman, Neli, Shi, Dan, Padgett, William L, Daly, John W, Jacobson, Kenneth A

    Published in Journal of medicinal chemistry (19-01-1996)
    “…A novel class of non-nitrogen-containing heterocycles, the tetrahydrobenzothiophenones, was found to bind to adenosine receptors as antagonists in the…”
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  9. 9

    2-Substitution of N6-Benzyladenosine-5'-uronamides Enhances Selectivity for A3 Adenosine Receptors by Kim, Hea O, Ji, Xiao-duo, Siddiqi, Suhaib M, Olah, Mark E, Stiles, Gary L, Jacobson, Kenneth A

    Published in Journal of medicinal chemistry (14-10-1994)
    “…Adenosine derivatives bearing an N6-(3-iodobenzyl) group, reported to enhance the affinity of adenosine-5'-uronamide analogues as agonists at A3 adenosine…”
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  10. 10

    Comparative molecular field analysis of selective A3 adenosine receptor agonists by Siddiqi, S M, Pearlstein, R A, Sanders, L H, Jacobson, K A

    Published in Bioorganic & medicinal chemistry (01-10-1995)
    “…A series of 48 N6-benzyladenosine 5'-uronamide derivatives has been described recently as moderately selective A3 adenosine receptor agonists of nanomolar…”
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  11. 11

    Comparative molecular field analysis of selective A 3 adenosine receptor agonists by Siddiqi, Suhaib M., Pearlstein, Robert A., Sanders, Lawrence H., Jacobson, Kenneth A.

    Published in Bioorganic & medicinal chemistry (1995)
    “…A series of 48 N 6-benzyladenosine 5′-uronamide derivatives has been described recently as moderately selective A 3 adenosine receptor agonists of nanomolar…”
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  12. 12

    Synthesis of (1R,4S,5R)-endo-N,N-dimethyl-2-azabicyclo[2.2.1]methanamine by Jordis, Ulrich, Sauter, Fritz, Siddiqi, Suhaib M.

    Published in Journal of heterocyclic chemistry (01-12-1991)
    “…Starting from trans‐4‐hydroxy‐L‐proline, (1R,4S,5R)‐endo‐N,N‐dimethyl‐2‐azabicyclo[2.2.1]methanamine 1 has been synthesized. The target compound is precursor…”
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