Search Results - "Siddik Alom, Md"
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Predicting protein function and orientation on a gold nanoparticle surface using a residue-based affinity scale
Published in Nature communications (27-11-2022)“…The orientation adopted by proteins on nanoparticle surfaces determines the nanoparticle’s bioactivity and its interactions with living systems. Here, we…”
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Structure-Guided Antiviral Peptides Identification Targeting the HIV‑1 Integrase
Published in ACS Physical Chemistry Au (25-09-2024)“…HIV-1 integrase (IN), a major protein in the HIV life cycle responsible for integrating viral cDNA into the host DNA, represents a promising drug target. Small…”
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Quantitative Measurement of Multiprotein Nanoparticle Interactions Using NMR Spectroscopy
Published in Analytical chemistry (Washington) (07-09-2021)“…An effective intensity-based reference is a cornerstone for quantitative nuclear magnetic resonance (NMR) studies, as the molecular concentration is encoded in…”
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A review on structural, non-structural, and accessory proteins of SARS-CoV-2: Highlighting drug target sites
Published in Immunobiology (1979) (01-01-2023)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, is a highly transmittable and pathogenic human coronavirus that…”
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Predicting Protein Function and Orientation on a Gold Nanoparticle Surface Using a Residue‐Based Affinity Scale
Published in The FASEB journal (01-05-2022)“…Gold nanoparticles (AuNPs) associate strongly with proteins when used as a nanoscale drug carrier in vivo. It is recognized that the structure and function of…”
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Antioxidant assessment of agricultural produce using fluorescence techniques: a review
Published in Critical reviews in food science and nutrition (2023)“…The study of bioactive compounds like food antioxidants is getting huge attention and curiosity by researchers and other relevant stakeholders (e.g., food and…”
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Unraveling the impact of ORF3a Q57H mutation on SARS-CoV-2: insights from molecular dynamics
Published in Journal of biomolecular structure & dynamics (11-12-2024)“…ORF3a is a conserved accessory protein of SARS-CoV-2, linked to viral infection and pathogenesis, with acquired mutations at various locations. Previous…”
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A Host-guest System for Understanding Protein-nanoparticle Interactions
Published in Biophysical journal (07-02-2020)Get full text
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A Host-Guest System for Determining Residue Contributions to Protein Adsorption on Nanoparticles by NMR
Published 01-01-2020“…Nanoparticles have become increasingly useful in the fields of drug delivery and biosensing. In these applications, nanoparticles are frequently exposed to…”
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Dissertation