Search Results - "Siciliano, J."

Premutation allele pool in myotonic dystrophy type 2 by BACHINSKI, L. L, CZERNUSZEWICZ, T, RAMAGLI, L. S, SUOMINEN, T, SHRIVER, M. D, UDD, B, SICILIANO, M. J, KRAHE, R

“…The myotonic dystrophies (DM1, DM2) are the most common adult muscle diseases and are characterized by multisystem involvement. DM1 has been described in…”
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Effect of trace mineral source on lactation performance, claw integrity, and fertility of dairy cattle by Siciliano-Jones, J L, Socha, M T, Tomlinson, D J, DeFrain, J M

“…Two hundred fifty multiparous and primiparous cows were assigned to a study at approximately 70 d prepartum to determine the effect of trace mineral source on…”
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XRCC2 and XRCC3, New Human Rad51-Family Members, Promote Chromosome Stability and Protect against DNA Cross-Links and Other Damages by Liu, Nan, Lamerdin, Jane E, Tebbs, Robert S, Schild, David, Tucker, James D, Shen, M.Richard, Brookman, Kerry W, Siciliano, Michael J, Walter, Christi A, Fan, Wufang, Narayana, Lakshmi S, Zhou, Zi-Qiang, Adamson, Aaron W, Sorensen, Karen J, Chen, David J, Jones, Nigel J, Thompson, Larry H

“…The phenotypically similar hamster mutants irs1 and irs1SF exhibit high spontaneous chromosome instability and broad-spectrum mutagen sensitivity, including…”
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Instability of expanded CAG CAA repeats in spinocerebellar ataxia type 17 by RUI GAO, MATSUURA, Tohru, COOLBAUGH, Mary, ZÜHLKE, Christine, NAKAMURA, Koichiro, RASMUSSEN, Astrid, SICILIANO, Michael J, ASHIZAWA, Tetsuo, XI LIN

“…Trinucleotide repeat expansions are dynamic mutations causing many neurological disorders, and their instability is influenced by multiple factors. Repeat…”
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Cloning, expression, and characterization of the human eosinophil eotaxin receptor by Daugherty, B L, Siciliano, S J, DeMartino, J A, Malkowitz, L, Sirotina, A, Springer, M S

“…Although there is a mounting body of evidence that eosinophils are recruited to sites of allergic inflammation by a number of beta-chemokines, particularly…”
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CCR5, CXCR4, and CD4 Are Clustered and Closely Apposed on Microvilli of Human Macrophages and T Cells by Singer, I I, Scott, S, Kawka, D W, Chin, J, Daugherty, B L, DeMartino, J A, DiSalvo, J, Gould, S L, Lineberger, J E, Malkowitz, L, Miller, M D, Mitnaul, L, Siciliano, S J, Staruch, M J, Williams, H R, Zweerink, H J, Springer, M S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CCR5 Blockade Modulates Inflammation and Alloimmunity in Primates by Schroder, Carsten, Pierson, Richard N., III, Nguyen, Bao-Ngoc H, Kawka, Douglas W, Peterson, Laurence B, Wu, Guosheng, Zhang, Tianshu, Springer, Martin S, Siciliano, Sal J, Iliff, Susan, Ayala, Julia M, Lu, Min, Mudgett, John S, Lyons, Kathy, Mills, Sander G, Miller, Geraldine G, Singer, Irwin I, Azimzadeh, Agnes M, DeMartino, Julie A

“…Pharmacologic antagonism of CCR5, a chemokine receptor expressed on macrophages and activated T cells, is an effective antiviral therapy in patients with…”
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Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability by FORTUNE, M. T, VASSILOPOULOS, C, COOLBAUGH, M. I, SICILIANO, M. J, MONCKTON, D. G

“…Myotonic dystrophy type 1 (DM1) is one of a growing number of inherited human diseases whose molecular basis has been implicated as the expansion of a…”
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Binding and Functional Properties of Recombinant and Endogenous CXCR3 Chemokine Receptors by Weng, Y, Siciliano, S J, Waldburger, K E, Sirotina-Meisher, A, Staruch, M J, Daugherty, B L, Gould, S L, Springer, M S, DeMartino, J A

“…IP10 and MIG are two members of the CXC branch of the chemokine superfamily whose expression is dramatically up-regulated by interferon (IFN)-γ. The proteins…”
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Correction of Chromosomal Instability and Sensitivity to Diverse Mutagens by a Cloned cDNA of the XRCC3 DNA Repair Gene by Tebbs, R S, Zhao, Y, Tucker, J D, Scheerer, J B, Siciliano, M J, Hwang, M, Liu, N, Legerski, R J, Thompson, L H

“…The mutagen-sensitive CHO line irs1SF was previously isolated on the basis of hypersensitivity to ionizing radiation and was found to be chromosomally unstable…”
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Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia by Liu, Pu, Tarlé, Susan A., Hajra, Amitav, Claxton, David F., Marlton, Paula, Freedman, Matthew, Siciliano, Michael J., Collins, Francis S.

“…The pericentric inversion of chromosome 16 [inv(16)(p13q22)] is a characteristic karyotypic abnormality associated with acute myeloid leukemia, most commonly…”
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Two-Site Binding of C5a by its Receptor: An Alternative Binding Paradigm for G Protein-Coupled Receptors by Siciliano, Salvatore J., Rollins, Thomas E., DeMartino, Julie, Konteatis, Zenon, Malkowitz, Lorraine, Van Riper, Gail, Bondy, Steven, Rosen, Hugh, Springer, Martin S.

“…The guanine nucleotide-binding protein-coupled receptor superfamily binds a vast array of biological messengers including lipids, odorants, catecholamines,…”
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Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection by Veazey, Ronald S, Klasse, Per Johan, Ketas, Thomas J, Reeves, Jacqueline D, Piatak, Jr, Michael, Kunstman, Kevin, Kuhmann, Shawn E, Marx, Preston A, Lifson, Jeffrey D, Dufour, Jason, Mefford, Megan, Pandrea, Ivona, Wolinsky, Steven M, Doms, Robert W, DeMartino, Julie A, Siciliano, Salvatore J, Lyons, Kathy, Springer, Martin S, Moore, John P

“…Human immunodeficiency virus type 1 (HIV-1) fuses with cells after sequential interactions between its envelope glycoproteins, CD4 and a coreceptor, usually CC…”
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Regulation of a Neuronal Form of Focal Adhesion Kinase by Anandamide by Derkinderen, Pascal, Toutant, Madeleine, Burgaya, Ferran, Le Bert, Marc, Siciliano, Julio C., de Franciscis, Vittorio, Gelman, Michèle, Girault, Jean-Antoine

“…Anandamide is an endogenous ligand for central cannabinoid receptors and is released after neuronal depolarization. Anandamide increased protein tyrosine…”
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Hypermutable myotonic dystrophy CTG repeats in transgenic mice by Monckton, Darren G, Coolbaugh, Mary I, Ashizawa, Ken T, Siciliano, Michael J, Caskey, C. Thomas

“…Myotonic dystrophy (DM) is one of a growing number of inherited human disorders associated with the expansion of triplet repeat DNA sequences. Expanded alleles…”
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Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 1: Discovery and initial structure-activity relationships for 1-amino-2-phenyl-4-(piperidin-1-yl)butanes by DORN, Conrad P, FINKE, Paul E, DEMARTINO, Julie A, SICILIANO, Salvatore J, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael, OATES, Bryan, SCHLEIF, William A, EMINI, Emilio A, BUDHU, Richard J, MILLS, Sander G, MACCOSS, Malcolm, MALKOWITZ, Lorraine, SPRINGER, Martin S, DAUGHERTY, Bruce L, GOULD, Sandra L

“…Screening of the Merck sample collection for compounds with CCR5 receptor binding afforded…”
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Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 1: Discovery and sar study of 4-pyrazolylpiperidine side chains by SHEN, Dong-Ming, MIN SHU, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, SCHLEIF, William A, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael D, EMINI, Emilio A, MILLS, Sander G, CHAPMAN, Kevin T, MALKOWITZ, Lorraine, SPRINGER, Martin S, GOULD, Sandra L, DEMARTINO, Julie A, SICILIANO, Salvatore J, KWEI, Gloria Y

“…Replacement of the flexible connecting chains between the piperidine moiety and an aromatic group in previous CCR5 antagonists with heterocycles, such as…”
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A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1 by Siciliano, Salvatore J., Kuhmann, Shawn E., Weng, Youmin, Madani, Navid, Springer, Martin S., Lineberger, Janet E., Danzeisen, Renee, Miller, Michael D., Kavanaugh, Michael P., DeMartino, Julie A., Kabat, David

“…Like the CCR5 chemokine receptors of humans and rhesus macaques, the very homologous (∼98–99% identical) CCR5 of African green monkeys (AGMs) avidly binds…”
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Human Indolethylamine N-Methyltransferase: cDNA Cloning and Expression, Gene Cloning, and Chromosomal Localization by Thompson, Michael A., Moon, Eunpyo, Kim, Ung-Jin, Xu, Jingping, Siciliano, Michael J., Weinshilboum, Richard M.

“…Indolethylamine N-methyltransferase (INMT) catalyzes the N-methylation of tryptamine and structurally related compounds. We recently cloned and characterized…”
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TAL2, A Helix-Loop-Helix Gene Activated by the (7;9)(q34;q32) Translocation in Human T-Cell Leukemia by YING XIA, BROWN, L, YING-CHUAN YANG, C, TSOU TSAN, J, SICILIANO, M. J, ESPINOSA, R. III, LE BEAU, M. M, BAER, R. J

“…Tumor-specific alteration of the TAL1 gene occurs in almost 25% of patients with T-cell acute lymphoblastic leukemia (T-ALL). We now report the identification…”
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