Search Results - "Sichani, Azadeh Hamzehei"

Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons by Karnani, Mahesh M, Jackson, Jesse, Ayzenshtat, Inbal, Hamzehei Sichani, Azadeh, Manoocheri, Kasra, Kim, Samuel, Yuste, Rafael

“…Inhibitory interneurons in the neocortex often connect in a promiscuous and extensive fashion, extending a "blanket of inhibition" on the circuit. This raises…”
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The direct basal ganglia pathway is hyperfunctional in focal dystonia by Simonyan, Kristina, Cho, Hyun, Hamzehei Sichani, Azadeh, Rubien-Thomas, Estee, Hallett, Mark

“…See Fujita and Eidelberg (doi:10.1093/brain/awx305) for a scientific commentary on this article. Focal dystonias are the most common type of isolated dystonia…”
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Efficacy and Safety of Sodium Oxybate in Isolated Focal Laryngeal Dystonia: A Phase IIb Double-Blind Placebo-Controlled Cross-Over Randomized Clinical Trial by Simonyan, Kristina, O'Flynn, Lena C, Hamzehei Sichani, Azadeh, Frucht, Steven J, Rumbach, Anna F, Sharma, Nutan, Song, Phillip C, Worthley, Alexis

“…To examine the efficacy and safety of sodium oxybate versus placebo in a phase IIb randomized double-blind placebo-controlled 2-period cross-over clinical…”
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A novel therapeutic agent, sodium oxybate, improves dystonic symptoms via reduced network-wide activity by Simonyan, Kristina, Frucht, Steven J., Blitzer, Andrew, Sichani, Azadeh Hamzehei, Rumbach, Anna F.

“…Oral medications for the treatment of dystonia are not established. Currently, symptoms of focal dystonia are managed with botulinum toxin injections into the…”
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Genetic Risk Factors in Isolated Dystonia Escape Genome‐Wide Association Studies by Laabs, Björn‐Hergen, Lohmann, Katja, Vollstedt, Eva‐Juliane, Reinberger, Tobias, Nuxoll, Lisa‐Marie, Kilic‐Berkmen, Gamze, Perlmutter, Joel S., Loens, Sebastian, Cruchaga, Carlos, Franke, Andre, Dobricic, Valerija, Hinrichs, Frauke, Grözinger, Anne, Altenmüller, Eckart, Bellows, Steven, Boesch, Sylvia, Bressman, Susan B., Duque, Kevin R., Espay, Alberto J., Ferbert, Andreas, Feuerstein, Jeanne S., Frank, Samuel, Gasser, Thomas, Haslinger, Bernhard, Jech, Robert, Kaiser, Frank, Kamm, Christoph, Kollewe, Katja, Kühn, Andrea A., LeDoux, Mark S., Lohmann, Ebba, Mahajan, Abhimanyu, Münchau, Alexander, Multhaupt‐Buell, Trisha, Pantelyat, Alexander, Pirio Richardson, Sarah E., Raymond, Deborah, Reich, Stephen G., Saunders Pullman, Rachel, Schormair, Barbara, Sharma, Nutan, Sichani, Azadeh Hamzehei, Simonyan, Kristina, Volkmann, Jens, Wagle Shukla, Aparna, Winkelmann, Juliane, Wright, Laura J., Zech, Michael, Zeuner, Kirsten E., Zittel, Simone, Kasten, Meike, Sun, Yan V., Bäumer, Tobias, Brüggemann, Norbert, Ozelius, Laurie J., Jinnah, Hyder A., Klein, Christine, König, Inke R.

“…Background Despite considerable heritability, previous smaller genome‐wide association studies (GWASs) have not identified any robust genetic risk factors for…”
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