Search Results - "Sicard, Kenneth"

Effects of hypoxia, hyperoxia, and hypercapnia on baseline and stimulus-evoked BOLD, CBF, and CMRO2 in spontaneously breathing animals by Sicard, Kenneth M, Duong, Timothy Q

“…Functional magnetic resonance imaging (fMRI) was used to investigate the effects of inspired hypoxic, hyperoxic, and hypercapnic gases on baseline and…”
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Normobaric hyperoxia delays perfusion diffusion mismatch evolution, reduces infarct volume, and differentially affects neuronal cell death pathways after suture middle cerebral artery occlusion in rats by Henninger, Nils, Bouley, James, Nelligan, Julia M, Sicard, Kenneth M, Fisher, Marc

“…Normobaric hyperoxia (NBO) has been shown to extend the reperfusion window after focal cerebral ischemia. Employing diffusion (DWI)- and perfusion…”
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Long-term changes of functional MRI-based brain function, behavioral status, and histopathology after transient focal cerebral ischemia in rats by SICARD, Kenneth M, HENNINGER, Nils, FISHER, Marc, DUONG, Timothy Q, FERRIS, Craig F

“…The relation between recovery of brain function and neurological status after clinical and experimental cerebral ischemia is incompletely characterized. We…”
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Imaging oxygen consumption in forepaw somatosensory stimulation in rats under isoflurane anesthesia by Liu, Zhaohui M., Schmidt, Karl F., Sicard, Kenneth M., Duong, Timothy Q.

“…The cerebral metabolic rate of oxygen (CMRO2) was dynamically evaluated on a pixel‐by‐pixel basis in isoflurane‐anesthetized and spontaneously breathing rats…”
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Regional Cerebral Blood Flow and BOLD Responses in Conscious and Anesthetized Rats Under Basal and Hypercapnic Conditions: Implications for Functional MRI Studies by Sicard, Kenneth, Shen, Qiang, Brevard, Mathew E., Sullivan, Ross, Ferris, Craig F., King, Jean A., Duong, Timothy Q.

“…Anesthetics, widely used in magnetic resonance imaging (MRI) studies to avoid movement artifacts, could have profound effects on cerebral blood flow (CBF) and…”
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Enhancement in cognitive function recovery by granulocyte-colony stimulating factor in a rodent model of traumatic brain injury by Sikoglu, Elif M., Heffernan, Meghan E., Tam, Kelly, Sicard, Kenneth M., Bratane, Bernt T., Quan, Meina, Fisher, Marc, King, Jean A.

“…•G-CSF as an intervention for cognitive deficits associated with TBI, is proposed.•Significant improvement in performance by G-CSF treated animal one week…”
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Multi-modal approach for investigating brain and behavior changes in an animal model of traumatic brain injury by Heffernan, Meghan E, Huang, Wei, Sicard, Kenneth M, Bratane, Bernt T, Sikoglu, Elif M, Zhang, Nanyin, Fisher, Marc, King, Jean A

“…Use of novel approaches in imaging modalities is needed for enhancing diagnostic and therapeutic outcomes of persons with a traumatic brain injury (TBI). This…”
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Spectacular shrinking deficit: insights from multimodal magnetic resonance imaging after embolic middle cerebral artery occlusion in Sprague-Dawley rats by Henninger, Nils, Sicard, Kenneth M, Fisher, Marc

“…Almost no data is available on the serial changes in the brain after spectacular shrinking deficit (SSD) that may help understand this relatively rare clinical…”
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Visualization of Clot Lysis in a Rat Embolic Stroke Model: Application to Comparative Lytic Efficacy by WALVICK, Ronn P, BRATANE, Bernt T, HENNINGER, Nils, SICARD, Kenneth M, BOULEY, James, ZHANYANG YU, ENG LO, XIAOYING WANG, FISHER, Marc

“…The purpose of this study was to develop a novel MRI method for imaging clot lysis in a rat embolic stroke model and to compare tissue plasminogen activator…”
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Neuroprotective effect of hyperbaric oxygen therapy monitored by MR-imaging after embolic stroke in rats by Henninger, Nils, Küppers-Tiedt, Lea, Sicard, Kenneth M., Günther, Albrecht, Schneider, Dietmar, Schwab, Stefan

“…The potential neuroprotective effects of hyperbaric oxygen (HBO) were tested in an embolic model of focal cerebral ischemia with partially spontaneous…”
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Differential recovery of behavioral status and brain function assessed with functional magnetic resonance imaging after mild traumatic brain injury in the rat by Henninger, Nils, Sicard, Kenneth M, Li, Zhixin, Kulkarni, Praveen, Dützmann, Stephan, Urbanek, Christian, Schwab, Stefan, Fisher, Marc

“…OBJECTIVE:The relationship between cerebral integrity, recovery of brain function, and neurologic status after mild traumatic brain injury is incompletely…”
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Differential recovery of multimodal MRI and behavior after transient focal cerebral ischemia in rats by Sicard, Kenneth M, Henninger, Nils, Fisher, Marc, Duong, Timothy Q, Ferris, Craig F

“…The association between recovery of brain function and behavior after transient cerebral ischemia in animals and humans is incompletely characterized…”
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The proteasome inhibitor VELCADE ® reduces infarction in rat models of focal cerebral ischemia by Henninger, Nils, Sicard, Kenneth M., Bouley, James, Fisher, Marc, Stagliano, Nancy E.

“…The potential neuroprotective effects of VELCADE ® were investigated in two different models of focal cerebral ischemia. For time-window assessment, male…”
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Comparison of ischemic lesion evolution in embolic versus mechanical middle cerebral artery occlusion in sprague dawley rats using diffusion and perfusion imaging by HENNINGER, Nils, SICARD, Kenneth M, SCHMIDT, Karl F, BARDUTZKY, Jiirgen, FISHER, Marc

“…Differences among models in the temporal evolution of ischemia after middle cerebral artery occlusion (MCAO) in rats may considerably influence the results of…”
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Impaired spatial learning in a novel rat model of mild cerebral concussion injury by Henninger, Nils, Dützmann, Stephan, Sicard, Kenneth M., Kollmar, Rainer, Bardutzky, Jürgen, Schwab, Stefan

“…The aim of the present study was to develop a model of mild traumatic brain injury in the rat that mimics human concussive brain injury suitable to study…”
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Emerging drugs for acute ischemic stroke by Sicard, Kenneth M, Fisher, Marc

“…Stroke is no longer an untreatable condition, and its management is changing rapidly as new developments appear for acute treatments. The objective of this…”
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Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI by SCHMIDT, Karl F, FEBO, Marcelo, QIANG SHEN, FENG LUO, SICARD, Kenneth M, FERRIS, Craig F, STEIN, Elliot A, DUONG, Timothy Q

“…Physiological changes (such as heart rate and respiration rate) associated with strong pharmacological stimuli could change the…”
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A new model of thromboembolic stroke in the posterior circulation of the rat by Henninger, Nils, Eberius, Karl H., Sicard, Kenneth M., Kollmar, Rainer, Sommer, Clemens, Schwab, Stefan, Schäbitz, Wolf R.

“…The prognosis of vertebrobasilar occlusion is grave and therapeutic options are limited. The aim of the present study was to develop a new model of embolic…”
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A Genetic Mosaic in the Fruiting Stage of Armillaria gallica by Peabody, Robert B, Peabody, Diane Cope, Sicard, Kenneth M

“…Peabody, R. B., Peabody, D. C., and Sicard, K. M. 2000. A genetic mosaic in the fruiting stage of Armillaria gallica. The basidiome stage of Armillaria gallica…”
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Meningococcal Carriage Evaluation in Response to a Serogroup B Meningococcal Disease Outbreak and Mass Vaccination Campaign at a College—Rhode Island, 2015–2016 by Soeters, Heidi M., Whaley, Melissa, Alexander-Scott, Nicole, Kanadanian, Koren V., MacNeil, Jessica R., Martin, Stacey W., McNamara, Lucy A., Sicard, Kenneth, Vanner, Cynthia, Vuong, Jeni, Wang, Xin, Bandy, Utpala, Patel, Manisha

“…Background. Serogroup B meningococcal disease caused 7 US university outbreaks during 2013–2016. Neisseria meningitidis can be transmitted via asymptomatic…”
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