Inpatient glycemic control on the vascular surgery service

To describe a structured inpatient insulin management protocol and order set for glycemic control on a vascular surgery service. Patients admitted to the vascular surgery service with underlying diabetes were enrolled in a study of use of a preprinted basal-bolus insulin order set based on a total d...

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Bibliographic Details
Published in:	Endocrine practice Vol. 14; no. 2; p. 185
Main Authors:	Theilen, Brenda M, Gritzke, Kevin A, Knutsen, P Gaye, Riek, Amy E, McGill, Janet B, Sicard, Gregory A, Tobin, Garry S
Format:	Journal Article
Language:	English
Published:	United States 01-03-2008
Subjects:	Blood Glucose - metabolism Diabetes Mellitus - blood Diabetes Mellitus - drug therapy Drug Administration Schedule Female Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - therapeutic use Inpatients - statistics & numerical data Insulin - administration & dosage Insulin - analogs & derivatives Insulin - therapeutic use Insulin, Long-Acting Male Treatment Outcome Vascular Surgical Procedures
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Summary:	To describe a structured inpatient insulin management protocol and order set for glycemic control on a vascular surgery service. Patients admitted to the vascular surgery service with underlying diabetes were enrolled in a study of use of a preprinted basal-bolus insulin order set based on a total daily dose of 0.5 U/kg (0.25 U/kg of insulin glargine and 0.25 U/kg of insulin as part divided into 3 equal mealtime doses). Outcomes included the mean glycemic control at each of 5 established time intervals, the percentage of blood glucose measurements within the target range of 70 to 180 mg/dL, the incidence of hypoglycemia, and the insulin dosages. Historical control patients with diabetes from the same hospital service were used for comparison. Both the study group and the control group consisted of 26 patients. The number of finger-stick blood glucose measurements performed was 871 in the control group and 896 in the intervention group. The mean blood glucose level (+/- SD) for the intervention group was 149.4 +/- 50.7 mg/dL, in comparison with 165.2 +/- 64.4 mg/dL for the control group. The incidence of hypoglycemia decreased 50% in the intervention group-from 32 (4% of the finger-stick assessments in the control group) to 19 (2% of the finger-stick blood glucose measurements in the study group). The blood glucose target range of 70 to 180 mg/dL was achieved in 75% of the measurements in the study group versus 61% in the control group. The basal insulin dose was unchanged in 65% of the patients, and of the 9 patients requiring a change in the dose, 5 had the dose decreased by 10% and 4 had the dose increased by 10%. The use of a standardized basal-bolus weight-based insulin regimen was successful at achieving improved glycemic control as well as reducing the incidence of hypoglycemia in an inpatient population with diabetes.
ISSN:	1934-2403
DOI:	10.4158/ep.14.2.185