Search Results - "Sica, Simona"

Alternative donor transplants for severe aplastic anemia: current experience by Bacigalupo, Andrea, Sica, Simona

“…Abstract Patients with acquired severe aplastic anemia (SAA), who lack a human leukocyte antigen (HLA) identical sibling donor (SIB), have two therapeutic…”
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Eltrombopag for the treatment of poor graft function following allogeneic stem cell transplant: a retrospective multicenter study by Giammarco, Sabrina, Sica, Simona, Chiusolo, Patrizia, Laurenti, Luca, Sorá, Federica, Martino, Massimo, Metafuni, Elisabetta, Busca, Alessandro, Risitano, Antonio, Vallejo, Carlos, Bacigalupo, Andrea

“…This retrospective study assessed the effectiveness of eltrombopag (EPAG), a thrombopoietin receptor agonist, in the treatment of poor graft function (PGF)…”
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The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria by Röth, Alexander, Nishimura, Jun-ichi, Nagy, Zsolt, Gaàl-Weisinger, Julia, Panse, Jens, Yoon, Sung-Soo, Egyed, Miklos, Ichikawa, Satoshi, Ito, Yoshikazu, Kim, Jin Seok, Ninomiya, Haruhiko, Schrezenmeier, Hubert, Sica, Simona, Usuki, Kensuke, Sicre de Fontbrune, Flore, Soret, Juliette, Sostelly, Alexandre, Higginson, James, Dieckmann, Andreas, Gentile, Brittany, Anzures-Cabrera, Judith, Shinomiya, Kenji, Jordan, Gregor, Biedzka-Sarek, Marta, Klughammer, Barbara, Jahreis, Angelika, Bucher, Christoph, Peffault de Latour, Régis

“…Complement C5 inhibition is the standard of care (SoC) for patients with paroxysmal nocturnal hemoglobinuria (PNH) with significant clinical symptoms. Constant…”
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Editorial: The latest advances in transplantation for AML by Chiusolo, Patrizia, Ciceri, Fabio, Sica, Simona

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The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells by Longo, Pablo G., Laurenti, Luca, Gobessi, Stefania, Sica, Simona, Leone, Giuseppe, Efremov, Dimitar G.

“…Sustained engagement of the B-cell receptor (BCR) increases apoptosis resistance in chronic lymphocytic leukemia (CLL) B cells, whereas transient stimulation…”
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A multicenter total therapy strategy for de novo adult Philadelphia chromosome positive acute lymphoblastic leukemia patients. Final results of the GIMEMA LAL1509 protocol by Chiaretti, Sabina, Ansuinelli, Michela, Vitale, Antonella, Elia, Loredana, Matarazzo, Mabel, Piciocchi, Alfonso, Fazi, Paola, Di Raimondo, Francesco, Santoro, Lidia, Fabbiano, Francesco, Califano, Catello, Martinelli, Giovanni, Ronco, Francesca, Ferrara, Felicetto, Cascavilla, Nicola, Bigazzi, Catia, Tedeschi, Alessandra, Sica, Simona, Di Renzo, Nicola, Melpignano, Angela, Beltrami, Germana, Vignetti, Marco, Foa, Robin

“…The GIMEMA LAL1509 protocol, designed for adult (≥18-60 years) de novo Ph+ acute lymphoblastic leukemia patients, was based on a dasatinib plus steroids…”
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Should the BCRA1/2-mutations healthy carriers be valid candidates for hematopoietic stem cell donation? by Fresa, Alberto, Sica, Simona

“…It's still not clear whether the mutational status of BRCA-mutated healthy hematopoietic stem cells (HSCs) donors could have an impact on the engraftment…”
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CAR-T Cell Therapy in B-Cell Acute Lymphoblastic Leukemia by Testa, Ugo, Sica, Simona, Pelosi, Elvira, Castelli, Germana, Leone, Giuseppe

“…Treatment of refractory and relapsed (R/R) B acute lymphoblastic leukemia (B-ALL) is an unmet medical need in both children and adults. Studies carried out in…”
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Outcome of haploidentical versus matched sibling donors in hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation by Nagler, Arnon, Labopin, Myriam, Houhou, Mohamed, Aljurf, Mahmoud, Mousavi, Ashrafsadat, Hamladji, Rose-Marie, Al Zahrani, Mohsen, Bondarenko, Sergey, Arat, Mutlu, Angelucci, Emanuele, Koc, Yener, Gülbas, Zafer, Sica, Simona, Bourhis, Jean Henri, Canaani, Jonathan, Brissot, Eolia, Giebel, Sebastian, Mohty, Mohamad

“…Non-T-cell depleted haploidentical hematopoietic stem cell transplantation (HaploSCT) is being increasingly used in acute lymphoblastic leukemia (ALL) with…”
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Bone marrow versus mobilized peripheral blood stem cell graft in T-cell-replete haploidentical transplantation in acute lymphoblastic leukemia by Nagler, Arnon, Dholaria, Bhagirathbhai, Labopin, Myriam, Savani, Bipin N., Angelucci, Emanuele, Koc, Yener, Arat, Mutlu, Pioltelli, Pietro, Sica, Simona, Gülbas, Zafer, Tischer, Johanna, Bernasconi, Paolo, Pavlu, Jiri, Socié, Gerard, Blaise, Didier, Rigacci, Luigi, Martino, Massimo, Diez-Martin, Jose Luis, Perić, Zinaida, Giebel, Sebastian, Mohty, Mohamad

“…The ideal stem cell graft source remains unknown in haploidentical haematopietic cell transplantation (haplo-HCT) with posttransplantation cyclophosphamide…”
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Response to Rituximab-Based Therapy and Risk Factor Analysis in Epstein Barr Virus—Related Lymphoproliferative Disorder After Hematopoietic Stem Cell Transplant in Children and Adults: A Study From the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation by Styczynski, Jan, Gil, Lidia, Tridello, Gloria, Ljungman, Per, Donnelly, J. Peter, van der Velden, Walter, Omar, Hamdy, Martino, Rodrigo, Halkes, Constantijn, Faraci, Maura, Theunissen, Koen, Kalwak, Krzysztof, Hubacek, Petr, Sica, Simona, Nozzoli, Chiara, Fagioli, Franca, Matthes, Susanne, Diaz, Miguel A., Migliavacca, Maddalena, Balduzzi, Adriana, Tomaszewska, Agnieszka, de la Camara, Rafael, van Biezen, Anja, Hoek, Jennifer, Iacobelli, Simona, Einsele, Hermann, Cesaro, Simone

“…Background. The objective of this analysis was to investigate prognostic factors that influence the outcome of Epstein-Barr virus (EBV)—related posttransplant…”
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Second haploidentical stem cell transplantation for primary graft failure by Giammarco, Sabrina, Raiola, Anna Maria, Di Grazia, Carmen, Bregante, Stefania, Gualandi, Francesca, Varaldo, Riccardo, Chiusolo, Patrizia, Sora, Federica, Sica, Simona, Laurenti, Luca, Metafuni, Elisabetta, Innocenti, Idanna, Autore, Francesco, Murgia, Barbara, Bacigalupo, Andrea, Angelucci, Emanuele

“…We report the outcome of 19 patients who experienced primary graft failure (PrGF) after a haploidentical (HAPLO), unmanipulated bone marrow transplant. The…”
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Clinical and Psychological Factors to Consider in Achieving Treatment-Free Remission in Patients With Chronic Myeloid Leukemia by Breccia, Massimo, Abruzzese, Elisabetta, Annunziata, Mario, Luciano, Luigia, Sica, Simona

“…Treatment of chronic myeloid leukemia (CML) has evolved dramatically in recent years. In this regard, the introduction of second-generation tyrosine kinase…”
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Unlocking Predictive Power: Quantitative Assessment of CAR-T Expansion with Digital Droplet Polymerase Chain Reaction (ddPCR) by Galli, Eugenio, Viscovo, Marcello, Fosso, Federica, Pansini, Ilaria, Di Cesare, Giacomo, Iacovelli, Camilla, Maiolo, Elena, Sorà, Federica, Hohaus, Stefan, Sica, Simona, Bellesi, Silvia, Chiusolo, Patrizia

“…Flow cytometry (FCM) and quantitative PCR (qPCR) are conventional methods for assessing CAR-T expansion, while digital droplet PCR (ddPCR) is emerging as a…”
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Triple post transplant cyclophosphamide (PTCY) based GVHD prophylaxis: HLA matched versus HLA haploidentical transplants by Galli, Eugenio, Metafuni, Elisabetta, Giammarco, Sabrina, Limongiello, Maria Assunta, Innocenti, Idanna, Autore, Francesco, Laurenti, Luca, Sorà, Federica, Chiusolo, Patrizia, Teofili, Luciana, Bacigalupo, Andrea, Sica, Simona

“…We report a retrospective analysis of 198 allogeneic hematopoietic stem cell transplant (HSCT) recipients with post-transplant cyclophosphamide (PTCY),…”
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Hematopoietic stem cell transplantation: an Italian monocentric experience on the health assessment and eligibility of adult-related donors by Valentini, Caterina Giovanna, Ceglie, Sara, Fatone, Federica, Metafuni, Elisabetta, Pellegrino, Claudio, Chiusolo, Patrizia, Sica, Simona, Teofili, Luciana

“…Indications for HSCT are increasing worldwide, paralleled by a growing demand for donors of therapeutic cells. Herein, we report our real-world experience of…”
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Post-transplant cyclophosphamide in one-antigen mismatched unrelated donor transplantation versus haploidentical transplantation in acute myeloid leukemia: a study from the Acute Leukemia Working Party of the EBMT by Battipaglia, Giorgia, Galimard, Jacques-Emmanuel, Labopin, Myriam, Raiola, Anna Maria, Blaise, Didier, Ruggeri, Annalisa, Koc, Yener, Gülbas, Zafer, Vitek, Antonin, Sica, Simona, Diez-Martin, Jose Luiz, Castagna, Luca, Bruno, Benedetto, Rovira, Montserrat, Moiseev, Ivan, Martino, Massimo, Grillo, Giovanni, Araujo, Mercedes Colorado, Bulabois, Claude Eric, Nguyen, Stéphanie, Socié, Gerard, Arat, Mutlu, Pavlu, Jiri, Tischer, Johanna, Martin, Hans, Corral, Lucia Lopez, Choi, Goda, Forcade, Edouard, McDonald, Andrew, Pane, Fabrizio, Bazarbachi, Ali, Ciceri, Fabio, Nagler, Arnon, Mohty, Mohamad

“…Whether to choose Haploidentical (Haplo) or one-antigen mismatched unrelated donor (1Ag-MMUD) hematopoietic cell transplantation (HCT) with post-transplant…”
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Risk of SARS-CoV-2 infection in patients with hematologic diseases receiving tixagevimab/cilgavimab as pre-exposure prophylaxis in most recent Omicron sublineages era by Vergori, Alessandra, Cozzi Lepri, Alessandro, Chiuchiarelli, Marta, Mazzotta, Valentina, Metafuni, Elisabetta, Matusali, Giulia, Siciliano, Valentina, Paulicelli, Jessica, Alma, Eleonora, Siniscalchi, Agostina, Sica, Simona, Abruzzese, Elisabetta, Fantoni, Massimo, Antinori, Andrea, Cingolani, Antonella

“…•The 1-year incidence estimate of breakthrough infections (BTIs)/hospitalization/death was 24%.•A greater risk of incident BTIs was observed with BA.5 and…”
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Autologous stem cell transplantation as bridging therapy followed by CD19 CAR-T cells in relapsed-refractory large B cell lymphoma by Galli, Eugenio, Sorà, Federica, Hohaus, Stefan, Bellesi, Silvia, Autore, Francesco, Metafuni, Elisabetta, Innocenti, Idanna, Marra, John, Fresa, Alberto, Limongiello, Maria Assunta, Giammarco, Sabrina, Leccisotti, Lucia, Guarneri, Andrea, Chiusolo, Patrizia, Laurenti, Luca, Teofili, Luciana, Piccirillo, Nicola, Bacigalupo, Andrea, Sica, Simona

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Somatic mutations as markers of outcome after azacitidine and allogeneic stem cell transplantation in higher-risk myelodysplastic syndromes by Falconi, Giulia, Fabiani, Emiliano, Piciocchi, Alfonso, Criscuolo, Marianna, Fianchi, Luana, Lindfors Rossi, Elisa L., Finelli, Carlo, Cerqui, Elisa, Ottone, Tiziana, Molteni, Alfredo, Parma, Matteo, Santarone, Stella, Candoni, Anna, Sica, Simona, Leone, Giuseppe, Lo-Coco, Francesco, Voso, Maria Teresa

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