Search Results - "Sibilio, Annarita"
-
1
Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation
Published in eLife (20-04-2022)“…Chronic inflammation is a major cause of disease. Inflammation resolution is in part directed by the differential stability of mRNAs encoding pro-inflammatory…”
Get full text
Journal Article -
2
Intracellular Inactivation of Thyroid Hormone Is a Survival Mechanism for Muscle Stem Cell Proliferation and Lineage Progression
Published in Cell metabolism (02-12-2014)“…Precise control of the thyroid hormone (T3)-dependent transcriptional program is required by multiple cell systems, including muscle stem cells. Deciphering…”
Get full text
Journal Article -
3
Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies
Published in Nature communications (16-03-2017)“…Systemic treatment of cancer requires tumour-selective therapies that eliminate cancer cells yet preserve healthy tissues from undesired damage. Tumoral…”
Get full text
Journal Article -
4
The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration
Published in The Journal of clinical investigation (01-11-2010)“…The active thyroid hormone 3,5,3' triiodothyronine (T3) is a major regulator of skeletal muscle function. The deiodinase family of enzymes controls the…”
Get full text
Journal Article -
5
Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development
Published in iScience (18-02-2022)“…Upon tissue injury, cytokine expression reprogramming transiently remodels the inflammatory immune microenvironment to activate repair processes and…”
Get full text
Journal Article -
6
Electroporation of skeletal muscle induces danger signal release and antigen-presenting cell recruitment independently of DNA vaccine administration
Published in Expert opinion on biological therapy (01-11-2008)“…Plasmid DNA vaccination combined with electroporation (EP) provides a promising approach for the prevention of infectious diseases and for cancer…”
Get more information
Journal Article -
7
An Intimate Relationship between Thyroid Hormone and Skin: Regulation of Gene Expression
Published in Frontiers in endocrinology (Lausanne) (2013)“…Skin is the largest organ of the human body and plays a key role in protecting the individual from external insults. The barrier function of the skin is…”
Get full text
Journal Article -
8
β-Catenin Regulates Deiodinase Levels and Thyroid Hormone Signaling in Colon Cancer Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2012)“…Background & Aims Activation of the β-catenin/T-cell factor (TCF) complex occurs in most colon tumors, and its actions correlate with the neoplastic phenotype…”
Get full text
Journal Article -
9
Antitumor T‐cell function requires CPEB4‐mediated adaptation to chronic endoplasmic reticulum stress
Published in The EMBO journal (02-05-2023)“…Tumor growth is influenced by a complex network of interactions between multiple cell types in the tumor microenvironment (TME). These constrained conditions…”
Get full text
Journal Article -
10
Epigenetic control of type 2 and 3 deiodinases in myogenesis: role of Lysine-specific Demethylase enzyme and FoxO3
Published in Nucleic acids research (01-04-2013)“…The proliferation and differentiation of muscle precursor cells require myogenic regulatory factors and chromatin modifiers whose concerted action dynamically…”
Get full text
Journal Article -
11
Abstract PR009: Application of Liquid Biopsy-RECIST (LB-RECIST) criteria to track metastatic colorectal cancer (mCRC) molecular response in first-line (1L) setting: Findings from the PLATFORM-B study
Published in Clinical cancer research (13-11-2024)“…Abstract Introduction: Circulating tumor DNA (ctDNA) analysis is a minimally invasive and reproducible method to explore tumor molecular biology. Recently,…”
Get full text
Journal Article -
12
Abstract B038: Application of Liquid Biopsy-RECIST (LB-RECIST) criteria to track metastatic colorectal cancer (mCRC) molecular response in first-line (1L) setting: Findings from the PLATFORM-B study
Published in Clinical cancer research (13-11-2024)“…Abstract This abstract is being presented as a short talk in the scientific program. A full abstract is printed in the Proffered Abstracts section (PR009) of…”
Get full text
Journal Article -
13
Identification and functional characterization of a novel mutation in the NKX2-1 gene: comparison with the data in the literature
Published in Thyroid (New York, N.Y.) (01-06-2013)“…NKX2-1 mutations have been described in several patients with primary congenital hypothyroidism, respiratory distress, and benign hereditary chorea, which are…”
Get more information
Journal Article -
14
The Fox O3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration
Published in The Journal of clinical investigation (01-11-2010)“…The active thyroid hormone 3,5,3' triiodothyronine (T3) is a major regulator of skeletal muscle function. The deiodinase family of enzymes controls the…”
Get full text
Journal Article