Search Results - "Sibanda, L."

DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair by Sibanda, Bancinyane L., Chirgadze, Dimitri Y., Ascher, David B., Blundell, Tom L.

“…DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a central component of nonhomologous end joining (NHEJ), repairing DNA double-strand breaks that…”
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Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats by Sibanda, Bancinyane L, Chirgadze, Dimitri Y, Blundell, Tom L

“…Broken chromosomes arising from DNA double-strand breaks result from endogenous events such as the production of reactive oxygen species during cellular…”
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Secondary HIV self-test distribution increases male partner testing by Sibanda, Euphemia L, Mavhu, Webster

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Provider and female client economic costs of integrated sexual and reproductive health and HIV services in Zimbabwe by Mangenah, Collin, Sibanda, Euphemia L, Maringwa, Galven, Sithole, Justice, Gudukeya, Stephano, Mugurungi, Owen, Hatzold, Karin, Terris-Prestholt, Fern, Maheswaran, Hendramoorthy, Thirumurthy, Harsha, Cowan, Frances M

“…A retrospective facility-based costing study was undertaken to estimate the comparative cost per visit of five integrated sexual and reproductive health and…”
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Inequalities in uptake of HIV testing despite scale-up by Sibanda, Euphemia L, Taegtmeyer, Miriam

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Caries clusters at lesion‐severity thresholds: A Sierra Leone case study by Sibanda, L., Ghotane, S. G., Bernabe, E., Challacombe, S. J., Pitts, N. B., Gallagher, J. E.

“…Objectives Despite being almost entirely preventable, globally, dental caries is extremely prevalent. Moreover, dental caries will continue to present an even…”
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Preferences for oral-fluid-based or blood-based HIV self-testing and provider-delivered testing: an observational study among different populations in Zimbabwe by Mavhu, Webster, Makamba, Memory, Hatzold, Karin, Maringwa, Galven, Takaruza, Albert, Mutseta, Miriam, Ncube, Getrude, Cowan, Frances M, Sibanda, Euphemia L

“…There is limited data on client preferences for different HIV self-testing (HIVST) and provider-delivered testing options and associated factors. We explored…”
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Incidental finding of an accessory inferior alveolar nerve by Sibanda, L., Elledge, R., Twohig, E.M.

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Essence of religion, culture and indigenous language in a unified sexuality education system by Sibanda, Lidion, Chabata, Tichakunda V., Chari, Felix, Sibanda, Thelisisa L.

“…Abstract only…”
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Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery by Blundell, Tom L, Sibanda, Bancinyane L, Montalvão, Rinaldo Wander, Brewerton, Suzanne, Chelliah, Vijayalakshmi, Worth, Catherine L, Harmer, Nicholas J, Davies, Owen, Burke, David

“…Impressive progress in genome sequencing, protein expression and high-throughput crystallography and NMR has radically transformed the opportunities to use…”
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Crystal structure of an Xrcc4-DNA ligase IV complex by Pellegrini, Luca, Sibanda, Bancinyane L, Critchlow, Susan E, Begun, Jake, Pei, Xue Y, Jackson, Stephen P, Blundell, Tom L

“…A complex of two proteins, Xrcc4 and DNA ligase IV, plays a fundamental role in DNA non-homologous end joining (NHEJ), a cellular function required for…”
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Effect of non-monetary incentives on uptake of couples' counselling and testing among clients attending mobile HIV services in rural Zimbabwe: a cluster-randomised trial by Sibanda, Euphemia L, Tumushime, Mary, Mufuka, Juliet, Mavedzenge, Sue Napierala, Gudukeya, Stephano, Bautista-Arredondo, Sergio, Hatzold, Karin, Thirumurthy, Harsha, McCoy, Sandra I, Padian, Nancy, Copas, Andrew, Cowan, Frances M

“…Couples' HIV testing and counselling (CHTC) is associated with greater engagement with HIV prevention and care than individual testing and is cost-effective,…”
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"Well, not me, but other women do not register because..."- Barriers to seeking antenatal care in the context of prevention of mother-to-child transmission of HIV among Zimbabwean women: a mixed-methods study by Sibanda, Euphemia L, Bernays, Sarah, Weller, Ian V D, Hakim, James G, Cowan, Frances M

“…While barriers to uptake of antenatal care (ANC) among pregnant women have been explored, much less is known about how integrating prevention of…”
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Radiology demand and capacity: A stochastic analysis based on care pathways by Sibanda, L, Engel-Hills, P, Hering, E, Liu, Shaofeng

“…The definition of (care) pathways, their advantages and disadvantages and the associated theories since the 1950s have been reported. Important in the…”
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Does Trimethoprim-Sulfamethoxazole Prophylaxis for HIV Induce Bacterial Resistance to Other Antibiotic Classes? Results of a Systematic Review by Sibanda, Euphemia L., Weller, Ian V. D., Hakim, James G., Cowan, Frances M.

“…Background. Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis has long been recommended for immunosuppressed HIV-infected adults and children born to…”
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Analysis of zearalenone and α-zearalenol in animal feed using high-performance liquid chromatography by De Saeger, S, Sibanda, L, Van Peteghem, C

“…Different extraction and clean-up techniques used before HPLC analysis were compared in order to obtain a reliable method for the quantitative determination of…”
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‘I will choose when to test, where I want to test’: investigating young peopleʼs preferences for HIV self-testing in Malawi and Zimbabwe by Indravudh, Pitchaya P, Sibanda, Euphemia L, d’Elbée, Marc, Kumwenda, Moses K, Ringwald, Beate, Maringwa, Galven, Simwinga, Musonda, Nyirenda, Lot J, Johnson, Cheryl C, Hatzold, Karin, Terris-Prestholt, Fern, Taegtmeyer, Miriam

“…OBJECTIVES:The current study identifies young peopleʼs preferences for HIV self-testing (HIVST) delivery, determines the relative strength of preferences and…”
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The magnitude of loss to follow-up of HIV-exposed infants along the prevention of mother-to-child HIV transmission continuum of care: a systematic review and meta-analysis by SIBANDA, Euphemia L, WELLER, Ian V. D, HAKIM, James G, COWAN, Frances M

“…Although prevention of mother-to-child HIV transmission (PMTCT) programs are widely implemented, many children do not benefit from them because of loss to…”
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Structure of an Xrcc4–DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode by Doré, Andrew S., Furnham, Nicholas, Davies, Owen R., Sibanda, Bancinyane L., Chirgadze, Dimitri Y., Jackson, Stephen P., Pellegrini, Luca, Blundell, Tom L.

“…DNA ligase IV catalyses the final ligation step in the non-homologous end-joining (NHEJ) DNA repair pathway and requires interaction of the ligase with the…”
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An assessment of the Zimbabwe ministry of health and child welfare provider initiated HIV testing and counselling programme by Sibanda, Euphemia L, Hatzold, Karin, Mugurungi, Owen, Ncube, Getrude, Dupwa, Beatrice, Siraha, Pester, Madyira, Lydia K, Mangwiro, Alexio, Bhattacharya, Gaurav, Cowan, Frances M

“…Provider-initiated HIV testing and counselling (PITC) is widely recommended to ensure timely treatment of HIV. The Zimbabwe Ministry of Health introduced PITC…”
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