Search Results - "Sibéril, Sophie"

Autophagy Modulation by Viral Infections Influences Tumor Development by Leonardi, Lucas, Sibéril, Sophie, Alifano, Marco, Cremer, Isabelle, Joubert, Pierre-Emmanuel

“…Autophagy is a self-degradative process important for balancing cellular homeostasis at critical times in development and/or in response to nutrient stress…”
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Unraveling the complex interplay between anti-tumor immune response and autoimmunity mediated by B cells and autoantibodies in the era of anti-checkpoint monoclonal antibody therapies by Soussan, Sarah, Pupier, Guilhem, Cremer, Isabelle, Joubert, Pierre-Emmanuel, Sautès-Fridman, Catherine, Fridman, Wolf Herman, Sibéril, Sophie

“…The intricate relationship between anti-tumor immunity and autoimmunity is a complex yet crucial aspect of cancer biology. Tumor microenvironment often…”
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Human iNKT and MAIT cells exhibit a PLZF-dependent proapoptotic propensity that is counterbalanced by XIAP by Gérart, Stéphane, Sibéril, Sophie, Martin, Emmanuel, Lenoir, Christelle, Aguilar, Claire, Picard, Capucine, Lantz, Olivier, Fischer, Alain, Latour, Sylvain

“…Invariant natural killer (iNKT) T cells and mucosal-associated invariant T (MAIT) cells represent peculiar T-lymphocyte subpopulations with innate-like…”
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Immature and mature antibodies as defenders against cancer by Lacombe, Robin V., Sibéril, Sophie, Dimitrov, Jordan D.

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Effective control of Staphylococcus aureus lung infection despite tertiary lymphoid structure disorganisation by Regard, Lucile, Martin, Clémence, Teillaud, Jean-Luc, Lafoeste, Hélène, Vicaire, Hugues, Ladjemi, Maha Zohra, Ollame-Omvane, Emilie, Sibéril, Sophie, Burgel, Pierre-Régis

“…Tertiary lymphoid structures (TLS) are triggered by persistent bronchopulmonary infection with , but their roles remain elusive. The present study sought to…”
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Autophagy modulation by viruses: An important role in tumor progression by Leonardi, Lucas, Sibéril, Sophie, Alifano, Marco, Cremer, Isabelle, Joubert, Pierre-Emmanuel

“…Autophagy is an important process for cellular homeostasis at critical steps of development or in response to environmental stress. In the context of cancers,…”
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Tight Interplay Between Therapeutic Monoclonal Antibodies and the Tumour Microenvironment in Cancer Therapy by Riller, Quentin, Varthaman, Aditi, Sibéril, Sophie

“…Therapeutic monoclonal antibodies (mAb) have changed the landscape of cancer therapy. With advances in the understanding of tumour biology and its…”
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Involvement of regulatory B lymphocytes in susceptibility to autoimmune side effects of cancer immunotherapy by Soussan, Sarah, Sibéril, Sophie

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Impact of Depleting Therapeutic Monoclonal Antibodies on the Host Adaptive Immunity: A Bonus or a Malus? by Deligne, Claire, Milcent, Benoît, Josseaume, Nathalie, Teillaud, Jean-Luc, Sibéril, Sophie

“…Clinical responses to anti-tumor monoclonal antibody (mAb) treatment have been regarded for many years only as a consequence of the ability of mAbs to destroy…”
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Acute Influenza Infection Promotes Lung Tumor Growth by Reprogramming the Tumor Microenvironment by Garmendia, Irati, Varthaman, Aditi, Marmier, Solenne, Angrini, Mahmud, Matchoua, Ingrid, Darbois-Delahousse, Aurelie, Josseaume, Nathalie, Foy, Pierre-Emmanuel, Roumenina, Lubka T, Naouar, Naïra, Meylan, Maxime, Sibéril, Sophie, Russick, Jules, Joubert, Pierre-Emmanuel, Leroy, Karen, Damotte, Diane, Mansuet-Lupo, Audrey, Wislez, Marie, Alifano, Marco, Menger, Laurie, Garcia-Verdugo, Ignacio, Sallenave, Jean-Michel, Lantz, Olivier, Petitprez, Florent, Cremer, Isabelle

“…One billion people worldwide get flu every year, including patients with non-small cell lung cancer (NSCLC). However, the impact of acute influenza A virus…”
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Presence of T cells directed against CD20-derived peptides in healthy individuals and lymphoma patients by Milcent, Benoit, Josseaume, Nathalie, Riller, Quentin, Giglioli, Ilenia, Rabia, Emilia, Deligne, Claire, Latouche, Jean-Baptiste, Hamieh, Mohamad, Couture, Alexandre, Toutirais, Olivier, Lone, Yu-Chun, Jeger-Madiot, Raphaël, Graff-Dubois, Stéphanie, Amorim, Sandy, Loiseau, Pascale, Toubert, Antoine, Brice, Pauline, Thieblemont, Catherine, Teillaud, Jean-Luc, Sibéril, Sophie

“…Preclinical and clinical studies have suggested that cancer treatment with antitumor antibodies induces a specific adaptive T cell response. A central role in…”
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Intravenous immunoglobulin: an update on the clinical use and mechanisms of action by Negi, Vir-Singh, Elluru, Sriramulu, Sibéril, Sophie, Graff-Dubois, Stéphanie, Mouthon, Luc, Kazatchkine, Michel D, Lacroix-Desmazes, Sébastien, Bayry, Jagadeesh, Kaveri, Srini V

“…Initially used as a replacement therapy for immunodeficiency diseases, intravenous immunoglobulin (IVIg) is now widely used for a number of autoimmune and…”
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Human X-linked variable immunodeficiency caused by a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG by Rigaud, Stéphanie, Lopez-Granados, Eduardo, Sibéril, Sophie, Gloire, Geoffrey, Lambert, Nathalie, Lenoir, Christelle, Synaeve, Cindy, Stacey, Maria, Fugger, Lars, Stephan, Jean-Louis, Fischer, Alain, Picard, Capucine, Durandy, Anne, Chapel, Helen, Latour, Sylvain

“…The present study focuses on a large family with an X-linked immunodeficiency in which there are variable clinical and laboratory phenotypes, including…”
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FcγR: The key to optimize therapeutic antibodies? by Sibéril, Sophie, Dutertre, Charles-Antoine, Fridman, Wolf-Herman, Teillaud, Jean-Luc

“…Abstract The binding of IgG to receptors for the Fc region of IgG (FcγR) is a critical step for the initiation and the control of effector immune functions…”
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Isolation and characterization of anti-FcγRIII (CD16) llama single-domain antibodies that activate natural killer cells by Behar, Ghislaine, Sibéril, Sophie, Groulet, Agnès, Chames, Patrick, Pugnière, Martine, Boix, Charlotte, Sautès-Fridman, Catherine, Teillaud, Jean-Luc, Baty, Daniel

“…FcγRIII (CD16) plays an important role in the anti-tumor effects of therapeutic antibodies. Bi-specific antibodies (bsAbs) targeting FcγRIII represent a…”
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Intravenous immunoglobulin induces proliferation and immunoglobulin synthesis from B cells of patients with common variable immunodeficiency: A mechanism underlying the beneficial effect of IVIg in primary immunodeficiencies by Bayry, Jagadeesh, Fournier, Emilie M, Maddur, Mohan S, Vani, Janakiraman, Wootla, Bharath, Sibéril, Sophie, Dimitrov, Jordan D, Lacroix-Desmazes, Sébastien, Berdah, Mikael, Crabol, Yoann, Oksenhendler, Eric, Lévy, Yves, Mouthon, Luc, Sautès-Fridman, Catherine, Hermine, Olivier, Kaveri, Srini V

“…Abstract Common variable immunodeficiency (CVID) is associated with low serum immunoglobulin concentrations and an increased susceptibility to infections and…”
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Exploring the Role of Tertiary Lymphoid Structures Using a Mouse Model of Bacteria-Infected Lungs by Teillaud, Jean-Luc, Regard, Lucile, Martin, Clémence, Sibéril, Sophie, Burgel, Pierre-Régis

“…Animal models can be helpful tools for deciphering the generation, maintenance, and role of tertiary lymphoid structures (TLS) during infections or tumor…”
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Rescuing CD4+CD25+ regulatory T-cell functions in rheumatoid arthritis by cytokine-targeted monoclonal antibody therapy by Bayry, Jagadeesh, Sibéril, Sophie, Triebel, Frédéric, Tough, David F., Kaveri, Srini V.

“…CD4+CD25+ regulatory T cells (Tregs) play a crucial role in controlling the development of autoimmune diseases such as rheumatoid arthritis (RA). However,…”
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Activation of Human Peripheral IgM+ B Cells Is Transiently Inhibited by BCR-Independent Aggregation of FcγRIIB by Fournier, Emilie M., Sibéril, Sophie, Costes, Anne, Varin, Audrey, Fridman, Wolf-Herman, Teillaud, Jean-Luc, Sautès-Fridman, Catherine

“…Abstract Immune complexes can trigger a SHIP-1-independent proapoptotic signal in mouse class-switched IgG+ B cells and plasma cells by binding to FcγRIIB, in…”
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Selection of a human anti-RhD monoclonal antibody for therapeutic use: Impact of IgG glycosylation on activating and inhibitory FcγR functions by Sibéril, Sophie, de Romeuf, Christophe, Bihoreau, Nicolas, Fernandez, Nadine, Meterreau, Jean-Luc, Regenman, Annie, Nony, Emmanuel, Gaucher, Christine, Glacet, Arnaud, Jorieux, Sylvie, Klein, Philippe, Hogarth, Mark P., Fridman, Wolf-Herman, Bourel, Dominique, Béliard, Roland, Teillaud, Jean-Luc

“…The substitution of plasmatic anti-RhD polyclonal antibodies by a monoclonal antibody (mAb) for preventing the hemolytic disease of the newborn (HDN) is an…”
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