Search Results - "Siannis, Fotios"

Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer by Linardou, Helena, PhD, Dahabreh, Issa J, MD, Kanaloupiti, Dimitra, MD, Siannis, Fotios, PhD, Bafaloukos, Dimitrios, MD, Kosmidis, Paris, MD, Papadimitriou, Christos A, MD, Murray, Samuel, Dr

“…Summary Background Somatic mutations of the k-RAS oncogene have been assessed as a mechanism of de-novo resistance to epidermal growth factor receptor (EGFR)…”
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Trastuzumab in the Adjuvant Treatment of Early‐Stage Breast Cancer: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials by Dahabreh, Issa J., Linardou, Helen, Siannis, Fotios, Fountzilas, George, Murray, Samuel

“…Learning Objectives After completing this course, the reader will be able to: Summarize the main characteristics and findings of randomized controlled trials…”
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Somatic EGFR Mutation and Gene Copy Gain as Predictive Biomarkers for Response to Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer by DAHABREH, Issa J, LINARDOU, Helena, SIANNIS, Fotios, KOSMIDIS, Paris, BAFALOUKOS, Dimitrios, MURRAY, Samuel

“…Purpose: The aim of this systematic review and meta-analysis was to characterize common EGFR molecular aberrations as potential predictive biomarkers for…”
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Patterns of adjustment during the Covid-19 pandemic in Greece: the Resilient, the Rebels and the Internalizers by Anagnostopoulou, Tanya, Siannis, Fotios, Kyriafinis, Dimitrios, Sela, Marjus

“…This study explored the patterns of adjustment to the quarantine restrictions imposed during the first Covid-19 wave in Greece. The sample comprised 1377…”
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Preservation of the mitral valve apparatus: evidence synthesis and critical reappraisal of surgical techniques by Athanasiou, Thanos, Chow, Andre, Rao, Christopher, Aziz, Omer, Siannis, Fotios, Ali, Ayyaz, Darzi, Ara, Wells, Francis

“…Sub-valvular apparatus preservation after mitral valve replacement is not a new concept, yet to date there has been no quantification of its clinical…”
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Applications of a Parametric Model for Informative Censoring by Siannis, Fotios

“…In this article, we explore the use of a parametric model (for analyzing survival data) which is defined to allow sensitivity analysis for the presence of…”
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HLA markers for susceptibility and expression in scleroderma by GLADMAN, Dafna D, KUNG, Tabitha N, SIANNIS, Fotios, PELLETT, Fawnda, FAREWELL, Vernon T, LEE, Peter

“…OBJECTIVE: Reported associations between HLA alleles and both susceptibility to and features of scleroderma have been conflicting. Our objective was (1) to…”
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Heterogeneity in meta-analysis: a comprehensive overview by Stogiannis, Dimitris, Siannis, Fotios, Androulakis, Emmanouil

“…In recent years, meta-analysis has evolved to a critically important field of Statistics, and has significant applications in Medicine and Health Sciences. In…”
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Sensitivity analysis for multiple right censoring processes: Investigating mortality in psoriatic arthritis by Siannis, Fotios

“…In a mortality study in psoriatic arthritis (PsA), censored observations are generated from the fact that patients fail to attend their scheduled appointments…”
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Does preservation of the sub-valvular apparatus during mitral valve replacement affect long-term survival and quality of life? A Microsimulation Study by Rao, Christopher, Hart, Jonathan, Chow, Andre, Siannis, Fotios, Tsalafouta, Polyxeni, Murtuza, Bari, Darzi, Ara, Wells, Frank C, Athanasiou, Thanos

“…Techniques to preserve the sub-valvular apparatus in order to reduce morbidity and mortality following mitral valve replacement have been frequently reported…”
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Modelling competing risks data with missing cause of failure by Bakoyannis, Giorgos, Siannis, Fotios, Touloumi, Giota

“…When competing risks data arise, information on the actual cause of failure for some subjects might be missing. Therefore, a cause‐specific proportional…”
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A semi-competing risks model for data with interval-censoring and informative observation: An application to the MRC cognitive function and ageing study by Barrett, Jessica K., Siannis, Fotios, Farewell, Vern T.

“…Semi‐competing risks data occur frequently in medical research when interest is in simultaneous modelling of two or more processes, one of which may censor the…”
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Folate Pathway Enzyme Gene Polymorphisms and the Efficacy and Toxicity of Methotrexate in Psoriatic Arthritis by CHANDRAN, Vinod, SIANNIS, Fotios, RAHMAN, Proton, PELLETT, Fawnda J, FAREWELL, Vernon T, GLADMAN, Dafna D

“…To determine the association between folate pathway gene polymorphisms and the effectiveness, toxicity, and drug survival of methotrexate (MTX) in psoriatic…”
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Two-stage meta-analysis of survival data from individual participants using percentile ratios by Barrett, Jessica K., Farewell, Vern T., Siannis, Fotios, Tierney, Jayne, Higgins, Julian P. T.

“…Methods for individual participant data meta‐analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently,…”
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Sensitivity analysis for informative censoring in parametric survival models by Siannis, Fotios, Copas, John, Lu, Guobing

“…Most statistical methods for censored survival data assume there is no dependence between the lifetime and censoring mechanisms, an assumption which is often…”
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Sensitivity analysis for correlated survival models by Siannis, Fotios

“…In this thesis we introduce a model for informative censoring. We assume that the joint distribution of the failure and the censored times depends on a…”
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