Search Results - "Siani, Antonio"
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Phorbol Esters from the Latex of Euphorbia umbellata: Bioguided Isolation of Highly Potent HIV‑1 Latency Interrupters in Virus Reservoir Cells
Published in Journal of natural products (Washington, D.C.) (28-05-2021)“…Three known compounds, 20-deoxyphorbol-5β-hydroxy-12-tiglate-13-isobutyrate (1), 20-deoxyphorbol-5β-hydroxy-12-tiglate-13-phenylacetate (2), and…”
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Reactivation of latent HIV-1 in vitro using an ethanolic extract from Euphorbia umbellata (Euphorbiaceae) latex
Published in PloS one (27-11-2018)“…Euphorbia umbellata (E. umbellata) belongs to Euphorbiaceae family, popularly known as Janauba, and its latex contains a combination of phorbol esters with…”
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HIV latency-reversing activity of latex from Euphorbia umbellata (Pax) Bruyns and three diterpenes isolated from this species
Published in Natural product research (20-06-2024)“…Two unusual phorbol esters, namely 20-deoxyphorbol-3,4,12-triacetate-13-phenylacetate ( ) and phorbol-3,4,12,13-tetraacetate-20-phenylacetate ( ) plus…”
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Isolation of ursolic acid from apple peels by high speed counter-current chromatography
Published in Food chemistry (01-01-2008)“…Cuticular waxes of four varieties of Malus domestica were investigated regarding their content of ursolic acid. Peels from Fuji, Gala, Smith and Granny Smith…”
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Polyphenol Profile and Quantitative Assessment of the Flavonoid Kaempferitrin in Wild and Cultivated Brazilian Amazonian Uncaria guianensis (Rubiaceae)
Published in Journal of the Brazilian Chemical Society (01-08-2021)“…The Amazonian Rubiaceae species Uncaria guianensis (UG) is locally used as antiinflammatory, antitumor, antidiabetic, anti-ulcers, and others. The phenolic…”
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POLYPHENOL AND TRITERPENOID CONSTITUENTS OF Eugenia florida DC. (MYRTACEAE) LEAVES AND THEIR ANTIOXIDANT AND CYTOTOXIC POTENTIAL
Published in Química Nova (01-12-2018)“…Leaves of Eugenia florida DC. have been used in folk medicine as hypotensive, hypoglycemic, antipyretic and for gastrointestinal disorders, among others. In…”
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Anti-inflammatory effects of methyl ursolate obtained from a chemically derived crude extract of apple peels: potential use in rheumatoid arthritis
Published in Archives of pharmacal research (01-11-2014)“…Ursolic acid (UA), a pentacyclic triterpene acid found in apple peels ( Malus domestica , Borkh, Rosaceae), has a large spectrum of pharmacological effects…”
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Anti-inflammatory activity of essential oils from Syzygium cumini and Psidium guajava
Published in Pharmaceutical biology (01-07-2013)“…Despite the many biological activities reported for essential oils, their anti-inflammatory ability is relatively underexplored considering the wide variation…”
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Trans-β-Caryophyllene : An Effective Antileishmanial Compound Found in Commercial Copaiba Oil (Copaifera spp.)
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…This study investigated the leishmanicidal activity against Leishmania amazonensis of four commercial oils from Copaifera spp. named as C1, C2, C3, and C4, the…”
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Production of antiretroviral drugs in middle- and low-income countries
Published in Antiviral therapy (01-01-2014)“…This review outlines the main issues concerning the production of antiretroviral (ARV) drugs in middle- and low-income countries and the relevant political,…”
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Integrative Analysis Based on HPLC-DAD-MS/MS and NMR of Bertholletia excelsa Bark Biomass Residues: Determination of Ellagic Acid Derivatives
Published in Journal of the Brazilian Chemical Society (01-04-2019)“…Bertholletia excelsa Bonpl. (Lecythidaceae) is a South American tree worldwide known for providing the Brazil nuts. In the Amazon Region, B. excelsa is found…”
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Bioconversion of R-(+)-limonene to perillic acid by the yeast Yarrowia lipolytica
Published in Brazilian journal of microbiology (01-12-2013)“…Perillyl derivatives are increasingly important due to their flavouring and antimicrobial properties as well as their potential as anticancer agents. These…”
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Antiviral and Virucidal Activities of Uncaria tomentosa (Cat's Claw) against the Chikungunya Virus
Published in Viruses (27-02-2024)“…(UT) is a medicinal plant popularly known as cat's claw belonging to the Rubiaceae family that has been reported to display antiviral and anti-inflammatory…”
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Immunomodulating and antiviral activities of Uncaria tomentosa on human monocytes infected with Dengue Virus-2
Published in International immunopharmacology (01-03-2008)“…Uncaria tomentosa (Willd.) DC., a large woody vine native to the Amazon and Central American rainforests has been used medicinally by indigenous peoples since…”
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Efficiency and selectivity of triterpene acid extraction from decoctions and tinctures prepared from apple peels
Published in Pharmacognosy Magazine (01-05-2014)“…This study assessed the extraction efficiency of ursolic (UA) and oleanolic acids (OA), as well as the total phenols in aqueous and hydroethanolic extracts of…”
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Optimized Kaempferitrin Isolation from Uncaria guianensis Leaves by Solid-Phase Extraction
Published in Journal of liquid chromatography & related technologies (25-02-2015)“…A simple and low-cost solid-phase extraction methodology for isolating the bioactive flavonoid kaempferitrin from a defatted fraction of the Uncaria guianensis…”
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A botanical census on pyrrolizidine alkaloid-producing species in Brazilian herbaria: data set for a potential health risk indication
Published in Rodriguésia (2020)“…Abstract This study accessed the informational potential of herbaria collections as a tool for establishing an indication of the distribution of species that…”
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Selective and cost-effective protocol to separate bioactive triterpene acids from plant matrices using alkalinized ethanol: Application to leaves of Myrtaceae species
Published in Pharmacognosy Magazine (01-07-2015)“…Triterpenes as betulinic (BA), oleanolic (OA) and ursolic acids (UA) have increasingly gained therapeutic relevance due to their wide scope of pharmacological…”
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Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7
Published in Memórias do Instituto Oswaldo Cruz (01-06-2017)“…Dengue fever may present hemorrhages and cavitary effusions as result of exacerbated immune responses. We investigated hydro-alcoholic extracts from leaves…”
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Essential oils of four Myrtaceae species from the Brazilian southeast
Published in Biochemical systematics and ecology (01-12-2010)“…The essential oils of the leaves of Eugenia acutata, Eugenia candolleana, Eugenia copacabanensis and Myrcia splendens (Myrtaceae) from Brazil’s southeastern…”
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