Search Results - "Siahaan, T.J."

The effect of conformation on the solution stability of linear vs. cyclic RGD peptides by Bogdanowich-Knipp, S.J., Jois, D.S.S., Siahaan, T.J.

“…: The objective of this study was to evaluate the relationship between conformational flexibility and solution stability of a linear RGD peptide…”
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Syntheses of cyclic prodrugs of RGD peptidomimetics with various macrocyclic ring sizes: evaluation of physicochemical, transport and antithrombic properties by He, H.T., Xu, C.R., Song, X., Siahaan, T.J.

“…: The objective of this work was to synthesize cyclic prodrugs 1a–d of RGD peptidomimetics 2a–d with various ring sizes (n[CH2] = 1, 3, 5 and 7) and to…”
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Synthesis and conformational analysis of a coumarinic acid-based cyclic prodrug of an opioid peptide with modified sensitivity to esterase-catalyzed bioconversion by Ouyang, H., Borchardt, R.T., Siahaan, T.J., Vander Velde, D.G.

“…: The coumarinic acid‐based cyclic DADLE (H‐Tyr‐D‐Ala‐Gly‐Phe‐D‐Leu‐OH) prodrug 1a exhibited more favorable physicochemical properties than did DADLE for…”
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Secondary structure of a dynamic type I'β-hairpin peptide by Stotz, C.E., Borchardt, R.T., Middaugh, C.R., Siahaan, T.J., Vander Velde, D., Topp, E.M.

“…:  A spontaneously folding β‐hairpin peptide (Lys‐Lys‐Tyr‐Thr‐Val‐Ser‐Ile‐Asn‐Gly‐Lys‐Lys‐Ile‐Thr‐Val‐Ser‐Ile) and related cyclic…”
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Binding and internalization of an ICAM-1 peptide by the surface receptors of T cells by Gürsoy, R.N., Siahaan, T.J.

“…: The objective of this work was to evaluate the binding characteristics of a cyclic peptide, cyclo (1,…”
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E-Cadherin Peptide Sequence Recognition by Anti-E-Cadherin Antibody by Lutz, K.L., Siahaan, T.J.

“…Cadherins are calcium dependent glycoproteins involved in hemophilic cell-cell adhesion. To further elucidate the interaction between cadherins we have…”
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The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides by Gudmundsson, O.S., Jois, S. D. S., Velde, D. G. Vander, Siahaan, T.J., Borchardt, R.T., Wang, B.

“…: In an earlier study using Caco‐2 cells, an in vitro cell culture model of the intestinal mucosa, we have shown that the coumarinic‐based (3 and 4) and the…”
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Structural recognition of an ICAM-1 peptide by its receptor on the surface of T cells: conformational studies of cyclo (1, 12)-Pen-Pro-Arg-Gly-Gly-Ser-Val-Leu-Val-Thr-Gly-Cys-OH by Gürsoy, R.N., Jois, D. S. S., Siahaan, T.J.

“…: The purpose of this study is to elucidate the solution conformation of cyclic peptide 1 (cIBR), cyclo (1,…”
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Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker by Bak, A., Gudmundsson, O.S., Gangwar, S., Friis, G.J., Siahaan, T.J., Borchardt, R.T.

“…: The objective of this work was to synthesize the cyclic prodrugs 1 and 2 of [Leu5]‐enkephalin (Tyr‐Gly‐Gly‐Phe‐Leu‐OH) and DADLE…”
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The effect of conformation of the acyloxyalkoxy-based cyclic prodrugs of opioid peptides on their membrane permeability by Gudmundsson, O.S., Vander Velde, D.G., Jois, S.D.S., Bak, A., Siahaan, T.J., Borchardt, R.T.

“…: In an earlier study using Caco‐2 cells, an in vitro cell culture model of the intestinal mucosa, we have shown that the acyloxyalkoxy‐based cyclic prodrugs 3…”
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Modeling alternative binding registers of a minimal immunogenic peptide on two class II major histocompatibility complex (MHC II) molecules predicts polarized T-cell receptor (TCR) contact positions by Murray, J.S., Schountz, T., Ford, S.R., Tawde, M.D., Murray, J.S., Jois, S. D. S., Siahaan, T.J., Brown, J.C.

“…:  Several major histocompatibility complex class II (MHC II) complexes with known minimal immunogenic peptides have now been solved by X‐ray crystallography…”
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Effect of conformation on the conversion of cyclo-(1,7)-Gly-Arg-Gly-Asp-Ser-Pro-Asp-Gly-OH to its cyclic imide degradation product by Bogdanowich-knipp, S.J., Jois, S.D.S., Siahaan, T.J.

“…: The objective of this study was to explain the increased propensity for the conversion of cyclo‐(1,7)‐Gly‐Arg‐Gly‐Asp‐Ser‐Pro‐Asp‐Gly‐OH (1), a…”
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