Search Results - "Sia Wey, Yeo"
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Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina
Published in Investigative ophthalmology & visual science (01-06-2016)“…To characterize the mouse retina lacking fatty acid binding protein (FABP7-/-). Immunohistochemistry (IHC) was performed in 8-week-old mice to localize FABP7…”
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2
The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
Published in Scientific reports (12-02-2018)“…Diabetic retinopathy (DR) is a retinal microvascular disease characterized by inflammatory and angiogenic pathways. In this study, we evaluated NLRP3…”
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Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-11-2016)“…Anti‐angiogenic therapies using biological molecules that neutralize vascular endothelial growth factor‐A (VEGF‐A) have revolutionized treatment of retinal…”
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Gene-Based Therapeutics for Inherited Retinal Diseases
Published in Frontiers in genetics (07-01-2022)“…Inherited retinal diseases (IRDs) are a heterogenous group of orphan eye diseases that typically result from monogenic mutations and are considered attractive…”
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HTRA1 Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid
Published in International journal of molecular sciences (06-09-2022)“…High-temperature requirement A1 (HtrA1) has been identified as a disease-susceptibility gene for age-related macular degeneration (AMD) including polypoidal…”
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Gene-Based Therapeutics for Acquired Retinal Disease: Opportunities and Progress
Published in Frontiers in genetics (07-12-2021)“…Acquired retinal diseases such as age-related macular degeneration and diabetic retinopathy rank among the leading causes of blindness and visual loss…”
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Fluorescent Dye Labeling of Erythrocytes and Leukocytes for Studying the Flow Dynamics in Mouse Retinal Circulation
Published in Journal of visualized experiments (03-07-2017)“…The retinal and choroidal blood flow dynamics may provide insight into the pathophysiology and sequelae of various ocular diseases, such as glaucoma, diabetic…”
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Targeting key angiogenic pathways with a bispecific Cross MA b optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-05-2019)“…In July 2017, the journal issued an editorial expression of concern (https://doi.org/10.15252/emmm.201707895) to alert readers that the data in Figs 4 and 5…”
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9
Moesin as a Key Cytoskeleton Regulator in Corneal Fibrosis
Published in The ocular surface (01-04-2013)“…Abstract Purpose: Corneal fibrosis is the third leading cause of blindness worldwide. α-Smooth muscle actin (SMA), a marker of fibrosis, is closely regulated…”
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10
Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-07-2017)Get full text
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11
Targeting key angiogenic pathways with a bispecific Cross MA b optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-11-2016)“…Anti‐angiogenic therapies using biological molecules that neutralize vascular endothelial growth factor‐A (VEGF‐A) have revolutionized treatment of retinal…”
Get full text
Journal Article -
12
Potential of subconjunctival aflibercept in treating choroidal neovascularization
Published in Experimental eye research (01-10-2020)“…The study aimed to evaluate the intraocular pharmacokinetics and efficacy of aflibercept after subconjunctival injection in animal models for treating…”
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13
Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-05-2019)Get full text
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14
Fluorescent Dye Labeling of Erythrocytes and Leukocytes for Studying the Flow Dynamics in Mouse Retinal Circulation
Published in Journal of visualized experiments (03-07-2017)Get full text
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15
Erratum To: Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-05-2019)“…Graphical Abstract…”
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16
A Minimally Invasive Experimental Model of Acute Ocular Hypertension with Acute Angle Closure Characteristics
Published in Translational vision science & technology (22-06-2020)Get full text
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A Minimally Invasive Experimental Model of Acute Ocular Hypertension with Acute Angle Closure Characteristics
Published in Translational vision science & technology (01-06-2020)“…To describe a minimally invasive experimental model of acute ocular hypertension (OHT) with characteristics of acute angle closure (AAC). Adult C57/Bl6 mice (n…”
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18
Targeting key angiogenic pathways with a bispecific Cross MA b optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-07-2017)Get full text
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19
Erratum To: Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-07-2017)“…Graphical Abstract…”
Get full text
Journal Article