Search Results - "Si‐Tahar, Mustapha"

Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein by Guillon, Antoine, Brea‐Diakite, Deborah, Cezard, Adeline, Wacquiez, Alan, Baranek, Thomas, Bourgeais, Jérôme, Picou, Frédéric, Vasseur, Virginie, Meyer, Léa, Chevalier, Christophe, Auvet, Adrien, Carballido, José M, Nadal Desbarats, Lydie, Dingli, Florent, Turtoi, Andrei, Le Gouellec, Audrey, Fauvelle, Florence, Donchet, Amélie, Crépin, Thibaut, Hiemstra, Pieter S, Paget, Christophe, Loew, Damarys, Herault, Olivier, Naffakh, Nadia, Le Goffic, Ronan, Si‐Tahar, Mustapha

“…Influenza virus infection causes considerable morbidity and mortality, but current therapies have limited efficacy. We hypothesized that investigating the…”
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Molecularly Imprinted Hydrogels Selective to Ribavirin as New Drug Delivery Systems to Improve Efficiency of Antiviral Nucleoside Analogue: A Proof‐of‐Concept Study with Influenza A Virus by Ayari, Mohamed G., Favetta, Patrick, Warszycki, Dawid, Vasseur, Virginie, Hervé, Virginie, Degardin, Pierre, Carbonnier, Benjamin, Si‐Tahar, Mustapha, Agrofoglio, Luigi A.

“…This study describes the synthesis and evaluation of different imprinted hydrogels using ribavirin as template molecule. Ribavirin serves as a model molecule…”
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Influenza viruses and coronaviruses: Knowns, unknowns, and common research challenges by Terrier, Olivier, Si-Tahar, Mustapha, Ducatez, Mariette, Chevalier, Christophe, Pizzorno, Andrés, Le Goffic, Ronan, Crépin, Thibaut, Simon, Gaëlle, Naffakh, Nadia

“…The development of safe and effective vaccines in a record time after the emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a…”
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A loss‐of‐function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients by Pothlichet, Julien, Niewold, Timothy B., Vitour, Damien, Solhonne, Brigitte, Crow, Mary K., Si‐Tahar, Mustapha

“…Dysregulation of the antiviral immune response may contribute to autoimmune diseases. Here, we hypothesized that altered expression or function of MAVS, a key…”
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Neutrophils can disarm NK cell response through cleavage of NKp46 by Valayer, Alexandre, Brea, Deborah, Lajoie, Laurie, Avezard, Leslie, Combes‐Soia, Lucie, Labas, Valerie, Korkmaz, Brice, Thibault, Gilles, Baranek, Thomas, Si‐Tahar, Mustapha

“…Polymorphonuclear neutrophils (PMNs) can contribute to the regulation of the host immune response by crosstalk with innate and adaptive leukocytes, including…”
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Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations by Le Rouzic, Olivier, Pichavant, Muriel, Frealle, Emilie, Guillon, Antoine, Si-Tahar, Mustapha, Gosset, Philippe

“…Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways caused mainly by cigarette smoke exposure. COPD progression is…”
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Lung compartmentalization of inflammatory biomarkers in COVID-19-related ARDS by Jouan, Youenn, Baranek, Thomas, Si-Tahar, Mustapha, Paget, Christophe, Guillon, Antoine

“…[...]in our COVID-19 ARDS cohort, the median (quartile 1; quartile 3) ratio was highly elevated: 7355 (1959; 22433), compared to 20 in the study of Bendib et…”
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Cutting Edge: Innate Immune Response Triggered by Influenza A Virus Is Negatively Regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-Dependent Pathway by Pothlichet, Julien, Chignard, Michel, Si-Tahar, Mustapha

“…Influenza A virus (IAV) triggers a contagious respiratory disease that produces considerable lethality. Although this lethality is likely due to an excessive…”
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Cutting Edge: Influenza A Virus Activates TLR3-Dependent Inflammatory and RIG-I-Dependent Antiviral Responses in Human Lung Epithelial Cells by Le Goffic, Ronan, Pothlichet, Julien, Vitour, Damien, Fujita, Takashi, Meurs, Eliane, Chignard, Michel, Si-Tahar, Mustapha

“…Influenza A virus (IAV) triggers a contagious acute respiratory disease that causes considerable mortality annually. Recently, we established a role for the…”
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Poly-L-Lysine to Fight Antibiotic Resistances of Pseudomonas aeruginosa by Cezard, Adeline, Fouquenet, Delphine, Vasseur, Virginie, Jeannot, Katy, Launay, Fabien, Si-Tahar, Mustapha, Hervé, Virginie

“…is a major hospital-associated pathogen that can cause severe infections, most notably in patients with cystic fibrosis (CF) or those hospitalized in intensive…”
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Involvement of Toll-like Receptor 3 in the Immune Response of Lung Epithelial Cells to Double-stranded RNA and Influenza A Virus by Guillot, Loïc, Le Goffic, Ronan, Bloch, Sarah, Escriou, Nicolas, Akira, Shizuo, Chignard, Michel, Si-Tahar, Mustapha

“…Influenza A is a highly contagious single-stranded RNA virus that infects both the upper and lower respiratory tracts of humans. The host innate immune…”
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Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia by Le Goffic, Ronan, Balloy, Viviane, Lagranderie, Micheline, Alexopoulou, Lena, Escriou, Nicolas, Flavell, Richard, Chignard, Michel, Si-Tahar, Mustapha

“…Influenza A virus (IAV) is the etiological agent of a highly contagious acute respiratory disease that causes epidemics and considerable mortality annually…”
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Interleukin-22 Reduces Lung Inflammation during Influenza A Virus Infection and Protects against Secondary Bacterial Infection by Ivanov, Stoyan, Renneson, Joelle, Fontaine, Josette, Barthelemy, Adeline, Paget, Christophe, Fernandez, Elodie Macho, Blanc, Fany, De Trez, Carl, Van Maele, Laurye, Dumoutier, Laure, Huerre, Michel-René, Eberl, Gérard, Si-Tahar, Mustapha, Gosset, Pierre, Renauld, Jean Christophe, Sirard, Jean Claude, Faveeuw, Christelle, Trottein, François

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Kallikrein‐related peptidase 5 contributes to the remodeling and repair of bronchial epithelium by Lenga Ma Bonda, Woodys, Lavergne, Marion, Vasseur, Virginie, Brisson, Lucie, Roger, Sébastien, Legras, Antoine, Guillon, Antoine, Guyétant, Serge, Hiemstra, Pieter S., Si‐Tahar, Mustapha, Iochmann, Sophie, Reverdiau, Pascale

“…Inflammation, oxidative stress, and protease/protease inhibitor imbalance with excessive production of proteases are factors associated with pathogenesis of…”
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FPR2: A Novel Promising Target for the Treatment of Influenza by Alessi, Marie-Christine, Cenac, Nicolas, Si-Tahar, Mustapha, Riteau, Béatrice

“…The Formyl-peptide receptor-2 (FPR2) is a seven transmembrane G protein-coupled receptor, which plays an important role in sensing of bacteria and modulation…”
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Ten-year trends in intensive care admissions for respiratory infections in the elderly by Laporte, Lucile, Hermetet, Coralie, Jouan, Youenn, Gaborit, Christophe, Rouve, Emmanuelle, Shea, Kimberly M., Si-Tahar, Mustapha, Dequin, Pierre-François, Grammatico-Guillon, Leslie, Guillon, Antoine

“…Background The consequences of the ageing population concerning ICU hospitalisation need to be adequately described. We believe that this discussion should be…”
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Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response by Hassane, Maya, Jouan, Youenn, Creusat, Florent, Soulard, Daphnée, Boisseau, Chloé, Gonzalez, Loïc, Patin, Emmanuel C., Heuzé-Vourc’h, Nathalie, Sirard, Jean-Claude, Faveeuw, Christelle, Trottein, François, Si-Tahar, Mustapha, Baranek, Thomas, Paget, Christophe

“…Interleukin-7 (IL-7) is a critical cytokine in B- and T-lymphocyte development and maturation. Recent evidence suggests that IL-7 is a preferential homeostatic…”
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Innate sensing of HIV-infected cells by Lepelley, Alice, Louis, Stéphanie, Sourisseau, Marion, Law, Helen K W, Pothlichet, Julien, Schilte, Clémentine, Chaperot, Laurence, Plumas, Joël, Randall, Richard E, Si-Tahar, Mustapha, Mammano, Fabrizio, Albert, Matthew L, Schwartz, Olivier

“…Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid…”
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Control of Pseudomonas aeruginosa in the Lung Requires the Recognition of Either Lipopolysaccharide or Flagellin by Ramphal, Reuben, Balloy, Viviane, Jyot, Jeevan, Verma, Amrisha, Si-Tahar, Mustapha, Chignard, Michel

“…Acute lung infection due to Pseudomonas aeruginosa is an increasingly serious problem that results in high mortality especially in the compromised host. In…”
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Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases by Hamon, Yveline, Legowska, Monika, Hervé, Virginie, Dallet-Choisy, Sandrine, Marchand-Adam, Sylvain, Vanderlynden, Lise, Demonte, Michèle, Williams, Rich, Scott, Christopher J., Si-Tahar, Mustapha, Heuzé-Vourc'h, Nathalie, Lalmanach, Gilles, Jenne, Dieter E., Lesner, Adam, Gauthier, Francis, Korkmaz, Brice

“…The cysteine protease cathepsin C (CatC) activates granule-associated proinflammatory serine proteases in hematopoietic precursor cells. Its early inhibition…”
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