Search Results - "Shurin, Michael R"
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Cross-talk between HIF and PD-1/PD-L1 pathways in carcinogenesis and therapy
Published in The Journal of clinical investigation (01-05-2022)“…Tumor-associated hypoxia plays an important role in carcinogenesis and metastasis. The expression, activation, and stabilization of hypoxia-inducible…”
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Rapid Detection of SARS-CoV‑2 Antigens Using High-Purity Semiconducting Single-Walled Carbon Nanotube-Based Field-Effect Transistors
Published in ACS applied materials & interfaces (03-03-2021)“…Early diagnosis of SARS-CoV-2 infection is critical for facilitating proper containment procedures, and a rapid, sensitive antigen assay is a critical step in…”
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3
Dendritic cells in the cancer microenvironment
Published in Journal of Cancer (01-01-2013)“…The complexity of the tumor immunoenvironment is underscored by the emergence and discovery of different subsets of immune effectors and regulatory cells…”
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Tumor-derived factors modulating dendritic cell function
Published in Cancer Immunology, Immunotherapy (01-07-2016)“…Dendritic cells (DC) play unique and diverse roles in the tumor occurrence, development, progression and response to therapy. First of all, DC can actively…”
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Differential Antibody Response to mRNA COVID-19 Vaccines in Healthy Subjects
Published in Microbiology spectrum (03-09-2021)“…Knowledge about development and duration of virus-specific antibodies after COVID-19 vaccination is important for understanding how to limit the pandemic via…”
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Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model
Published in The Journal of immunology (1950) (01-03-2013)“…The antitumor effects of paclitaxel are generally attributed to the suppression of microtubule dynamics resulting in defects in cell division. New data…”
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7
Enzymatic oxidative biodegradation of nanoparticles: Mechanisms, significance and applications
Published in Toxicology and applied pharmacology (15-05-2016)“…Biopersistence of carbon nanotubes, graphene oxide (GO) and several other types of carbonaceous nanomaterials is an essential determinant of their health…”
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Chemotherapeutic Agents in Noncytotoxic Concentrations Increase Antigen Presentation by Dendritic Cells via an IL-12-Dependent Mechanism
Published in The Journal of immunology (1950) (01-07-2009)“…Antineoplastic chemotherapeutic agents may indirectly activate dendritic cells (DCs) by inducing the release of "danger" signals from dying tumor cells…”
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Clinical evaluation of systemic and local immune responses in cancer: time for integration
Published in Cancer Immunology, Immunotherapy (01-01-2014)“…The immune system has a dual role in cancer development and progression. On the one hand, it can eradicate emerging malignant cells, but on the other hand, it…”
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Tumor associated regulatory dendritic cells
Published in Seminars in cancer biology (01-08-2012)“…Abstract Immune effector and regulatory cells in the tumor microenvironment are key factors in tumor development and progression as the pathogenesis of cancer…”
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Impact of the Sensory Neurons on Melanoma Growth In Vivo
Published in PloS one (26-05-2016)“…Nerve endings are often identified within solid tumors, but their impact on the tumor growth and progression remains poorly understood. Emerging data suggests…”
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Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
Published in Journal of translational medicine (10-07-2009)“…The dose-delivery schedule of conventional chemotherapy, which determines its efficacy and toxicity, is based on the maximum tolerated dose. This strategy has…”
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13
New flow cytometric assays for monitoring cell-mediated cytotoxicity
Published in Expert review of vaccines (01-06-2010)“…The exact immunologic responses after vaccination that result in effective antitumor immunity have not yet been fully elucidated and the data from ex vivo…”
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Cyanidin-3-rutinoside, a Natural Polyphenol Antioxidant, Selectively Kills Leukemic Cells by Induction of Oxidative Stress
Published in The Journal of biological chemistry (04-05-2007)“…Anthocyanins are a group of naturally occurring phenolic compounds widely available in fruits and vegetables in human diets. They have broad biological…”
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15
Neuroimmune Regulation of Surgery-Associated Metastases
Published in Cells (Basel, Switzerland) (20-02-2021)“…Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data…”
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Carbon Nanotubes Enhance Metastatic Growth of Lung Carcinoma via Up-Regulation of Myeloid-Derived Suppressor Cells
Published in Small (Weinheim an der Bergstrasse, Germany) (27-05-2013)“…Metastatic establishment and growth of Lewis lung carcinoma is promoted by single‐walled carbon nanotubes (SWCNT) in C57BL6/J mice. The effect is mediated by…”
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Abnormal Expression of c-Myc Oncogene in NK Cells in Patients with Cancer
Published in International journal of molecular sciences (11-02-2019)“…Natural killer (NK) cells have received a lot of attention in recent years for the roles they play in immunity and particularly in antitumor immune responses…”
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Direct Effects of Carbon Nanotubes on Dendritic Cells Induce Immune Suppression Upon Pulmonary Exposure
Published in ACS nano (26-07-2011)“…Pharyngeal aspiration of single-walled carbon nanotubes (SWCNTs) caused inflammation, pulmonary damage, and an altered cytokine network in the lung. Local…”
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Tumor-Induced T Cell Polarization by Schwann Cells
Published in Cells (Basel, Switzerland) (01-11-2022)“…Nerve-cancer crosstalk resulting in either tumor neurogenesis or intratumoral neurodegeneration is critically controlled by Schwann cells, the principal glial…”
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Schwann cells in the normal and pathological lung microenvironment
Published in Frontiers in molecular biosciences (04-04-2024)“…The lungs are a key organ in the respiratory system. They are regulated by a complex network of nerves that control their development, structure, function, and…”
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