Search Results - "Shurin, G V"

ChemoImmunoModulation: immune regulation by the antineoplastic chemotherapeutic agents by Shurin, M R, Naiditch, H, Gutkin, D W, Umansky, V, Shurin, G V

“…Since 1948, when Farber et al. introduced aminopterin, the first chemotherapeutic agent, more than 100 such agents have come into use. Initially, antitumor…”
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Cytokine-mediated protection of human dendritic cells from prostate cancer-induced apoptosis is regulated by the Bcl-2 family of proteins by PIRTSKHALAISHVILI, G, SHURIN, G. V, ESCHE, C, CAI, Q, SALUP, R. R, BYKOVSKAIA, S. N, LOTZE, M. T, SHURIN, M. R

“…Prostate cancer is the most common cancer in men in the United States, and second in cancer-induced mortality. It is likely that tumour-induced…”
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Tumor's other immune targets: dendritic cells by Esche, Clemens, Lokshin, Anna, Shurin, Galina V., Gastman, Brian R., Rabinowich, Hannah, Watkins, Simon C., Lotze, Michael T., Shurin, Michael R.

“…The induction of apoptosis in T cells is one of several mechanisms by which tumors escape immune recognition. We have investigated whether tumors induce…”
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TNF-alpha protects dendritic cells from prostate cancer-induced apoptosis by Pirtskhalaishvili, G, Shurin, G V, Esche, C, Trump, D L, Shurin, M R

“…We have recently shown that human prostate cancer (PCa) cells induced apoptotic death of the most potent antigen-presenting cells, dendritic cells (DC), which…”
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Neuroblastoma-derived gangliosides inhibit dendritic cell generation and function by SHURIN, Galina V, SHURIN, Michael R, BYKOVSKAIA, Svetlana, SHOGAN, Jeffrey, LOTZE, Michael T, BARKSDALE, Edward M

“…Neuroblastoma (NB), a tumor of the sympathetic nervous system, is the most common extracranial solid tumor in children. NB-derived gangliosides inhibit the…”
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Lung cancer-derived bombesin-like peptides down-regulate the generation and function of human dendritic cells by Makarenkova, Valeria P., Shurin, Galina V., Tourkova, Irina L., Balkir, Levent, Pirtskhalaishvili, Georgi, Perez, Lori, Gerein, Valentin, Siegfried, Jill M., Shurin, Michael R.

“…Development of tumors is regulated by tumor-derived neuroendocrine factors, including bombesin-like peptides (BLP). We have evaluated neuroendocrine regulation…”
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Human prostate cancer regulates generation and maturation of monocyte-derived dendritic cells by Aalamian, Maryam, Pirtskhalaishvili, Georgi, Nunez, Anthony, Esche, Clemens, Shurin, Galina V., Huland, Edith, Huland, Hartwig, Shurin, Michael R.

“…Background The progression of prostate cancer is accompanied by a marked suppression of the immune system, including the apoptotic death of dendritic cells…”
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Human Small Cell Lung Carcinoma and Carcinoid Tumor Regulate Dendritic Cell Maturation and Function by Katsenelson, Nora S, Shurin, Galina V, Bykovskaia, Svetlana N, Shogan, Jeffrey, Shurin, Michael R

“…The induction of apoptosis in dendritic cells (DC) is a key mechanism by which tumors escape immune recognition and elimination. In fact, a number of studies…”
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Mechanisms of dendritic cell-induced T cell proliferation in the primary MLR assay by Tourkova, Irina L., Yurkovetsky, Zoya R., Shurin, Michael R., Shurin, Galina V.

“…DC are unique antigen presenting cells, and their ability to induce proliferation of T cells in a mixed leukocyte reaction (MLR) assay is commonly used for the…”
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Increased function and survival of IL-15-transduced human dendritic cells are mediated by up-regulation of IL-15Rα and Bcl-2 by Tourkova, Irina L., Yurkovetsky, Zoya R., Gambotto, Andrea, Makarenkova, Valeria P., Perez, Lori, Balkir, Levent, Robbins, Paul D., Shurin, Michael R., Shurin, Galina V.

“…It has been recently demonstrated that dendritic cells (DC) coincubated with interleukin (IL)‐15 express high levels of the Bcl‐2 family of proteins and…”
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Identification of delta- and mu-type opioid receptors on human and murine dendritic cells by Makarenkova, Valeria P, Esche, Clemens, Kost, Natalia V, Shurin, Galina V, Rabin, Bruce S, Zozulya, Andrey A, Shurin, Michael R

“…The purpose of this study was to evaluate μ- and δ-opioid receptors (OR) on human and murine dendritic cells (DC). Expression of μ- and δ-OR mRNA on DC was…”
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Tumor Necrosis Factor-α-promoted Expression of Bcl-2 and Inhibition of Mitochondrial Cytochrome c Release Mediate Resistance of Mature Dendritic Cells to Melanoma-induced Apoptosis by ESCHE, Clemens, SHURIN, Galina V, KIRKWOOD, John M, WANG, Gui-Qiang, RABINOWICH, Hannah, PIRTSKHALAISHVILI, Georgi, SHURIN, Michael R

“…Melanoma escapes host defenses through a variety of means, including the elimination of immune effector cells within the tumor microenvironment. We have…”
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Human prostate cancer blocks the generation of dendritic cells from CD34+ hematopoietic progenitors by Shurin, G V, Aalamian, M, Pirtskhalaishvili, G, Bykovskaia, S, Huland, E, Huland, H, Shurin, M R

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Human renal cell carcinoma inhibits dendritic cell maturation and functions by Song, E Y, Shurin, M R, Tourkova, I L, Chatta, G, Shurin, G V

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Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: Cytotoxicity or inflammation? by Menas, Autumn L., Yanamala, Naveena, Farcas, Mariana T., Russo, Maria, Friend, Sherri, Fournier, Philip M., Star, Alexander, Iavicoli, Ivo, Shurin, Galina V., Vogel, Ulla B., Fadeel, Bengt, Beezhold, Donald, Kisin, Elena R., Shvedova, Anna A.

“…Nanocellulose (NC) is emerging as a highly promising nanomaterial for a wide range of applications. Moreover, many types of NC are produced, each exhibiting a…”
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Low-dose Chemotherapeutic Agents Regulate Small Rho GTPase Activity in Dendritic Cells by SHURIN, Galina V, TOURKOVA, Irina L, SHURIN, Michael R

“…Conventional chemotherapy targets dividing tumor cells and might support antitumor immunity by providing tumor antigens from dying tumor cells to…”
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Graphene Oxide, But Not Fullerenes, Targets Immunoproteasomes and Suppresses Antigen Presentation by Dendritic Cells by Tkach, Alexey V., Yanamala, Naveena, Stanley, Shyla, Shurin, Michael R., Shurin, Galina V., Kisin, Elena R., Murray, Ashley R., Pareso, Samantha, Khaliullin, Timur, Kotchey, Gregg P., Castranova, Vincent, Mathur, Sanjay, Fadeel, Bengt, Star, Alexander, Kagan, Valerian E., Shvedova, Anna A.

“…Graphene oxide (GO) and C60‐ or C60‐TRIS fullerenes, internalized by murine dendritic cells (DCs), differently affect their abilities to present antigens to…”
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Graphene Oxide Attenuates Th2-Type Immune Responses, but Augments Airway Remodeling and Hyperresponsiveness in a Murine Model of Asthma by Shurin, Michael R, Yanamala, Naveena, Kisin, Elena R, Tkach, Alexey V, Shurin, Galina V, Murray, Ashley R, Leonard, Howard D, Reynolds, Jeffrey S, Gutkin, Dmirtiy W, Star, Alexander, Fadeel, Bengt, Savolainen, Kai, Kagan, Valerian E, Shvedova, Anna A

“…Several lines of evidence indicate that exposure to nanoparticles (NPs) is able to modify airway immune responses, thus facilitating the development of…”
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Direct Effects of Carbon Nanotubes on Dendritic Cells Induce Immune Suppression Upon Pulmonary Exposure by Tkach, Alexey V, Shurin, Galina V, Shurin, Michael R, Kisin, Elena R, Murray, Ashley R, Young, Shih-Houng, Star, Alexander, Fadeel, Bengt, Kagan, Valerian E, Shvedova, Anna A

“…Pharyngeal aspiration of single-walled carbon nanotubes (SWCNTs) caused inflammation, pulmonary damage, and an altered cytokine network in the lung. Local…”
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Loss of New Chemokine CXCL14 in Tumor Tissue Is Associated with Low Infiltration by Dendritic Cells (DC), while Restoration of Human CXCL14 Expression in Tumor Cells Causes Attraction of DC Both In Vitro and In Vivo by Shurin, Galina V, Ferris, Robert, Tourkova, Irina L, Perez, Lori, Lokshin, Anna, Balkir, Levent, Collins, Bobby, Chatta, Gurkamal S, Shurin, Michael R

“…Breast and kidney-expressed chemokine (BRAK) CXCL14 is a new CXC chemokine with unknown function and receptor selectivity. The majority of head and neck…”
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