Search Results - "Shun, Chia‐Tung"

Metabolic targeting of HIF-1α potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer by Wei, Tzu-Tang, Lin, Yi-Ting, Tang, Shao-Pu, Luo, Cong-Kai, Tsai, Chiou-Tsun, Shun, Chia-Tung, Chen, Ching-Chow

“…Drug resistance is a major problem limiting the efficacy of chemotherapy in cancer treatment, and the hypoxia-induced stabilization of HIF-1α plays a role in…”
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Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice Through Activating TNF‐α Pathway by Lin, Chin‐Hsien, Lin, Han‐Yi, Ho, En‐Pong, Ke, Yi‐Ci, Cheng, Mei‐Fang, Shiue, Chyng‐Yann, Wu, Chi‐Han, Liao, Peng‐Hsiang, Hsu, Angela Yu‐Huey, Chu, Li‐An, Liu, Ya‐Ding, Lin, Ya‐Hui, Tai, Yi‐Cheng, Shun, Chia‐Tung, Chiu, Han‐Mo, Wu, Ming‐Shiang

“…Background Leucine‐rich repeat kinase 2 (LRRK2) is a common risk gene for Parkinson's disease (PD) and inflammatory bowel disorders. However, the penetrance of…”
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Loss of proximal tubular transcription factor Krüppel-like factor 15 exacerbates kidney injury through loss of fatty acid oxidation by Piret, Sian E, Attallah, Ahmed A, Gu, Xiangchen, Guo, Yiqing, Gujarati, Nehaben A, Henein, Justina, Zollman, Amy, Hato, Takashi, Ma'ayan, Avi, Revelo, Monica P, Dickman, Kathleen G, Chen, Chung-Hsin, Shun, Chia-Tung, Rosenquist, Thomas A, He, John C, Mallipattu, Sandeep K

“…Loss of fatty acid β-oxidation (FAO) in the proximal tubule is a critical mediator of acute kidney injury and eventual fibrosis. However, transcriptional…”
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Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein by Cheng, Tsu-Yao, Yang, Yi-Chieh, Wang, Hsiu-Po, Tien, Yu-Wen, Shun, Chia-Tung, Huang, Hsin-Yi, Hsiao, Michael, Hua, Kuo-Tai

“…Pyruvate kinase muscle isozymes (PKMs) have crucial roles in regulating metabolic changes during carcinogenesis. A switch from PKM1 to PKM2 isoform was thought…”
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Aristolochic acid‐induced upper tract urothelial carcinoma in Taiwan: Clinical characteristics and outcomes by Chen, Chung‐Hsin, Dickman, Kathleen G., Huang, Chao‐Yuan, Moriya, Masaaki, Shun, Chia‐Tung, Tai, Huai‐Ching, Huang, Kuo‐How, Wang, Shuo‐Meng, Lee, Yuan‐Ju, Grollman, Arthur P., Pu, Yeong‐Shiau

“…Aristolochic acid (AA), a component of all Aristolochia‐based herbal medicines, is a potent nephrotoxin and human carcinogen associated with upper urinary…”
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Association Between Early Stage Colon Neoplasms and False-negative Results From the Fecal Immunochemical Test by Chiu, Han–Mo, Lee, Yi–Chia, Tu, Chia–Hung, Chen, Chien–Chuan, Tseng, Ping–Huei, Liang, Jin–Tung, Shun, Chia–Tung, Lin, Jaw–Town, Wu, Ming–Shiang

“…Background & Aims The fecal immunochemical test (FIT) can identify patients with advanced colorectal neoplasms, but it also has a high rate of false-negative…”
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Concomitant, bismuth quadruple, and 14-day triple therapy in the first-line treatment of Helicobacter pylori : a multicentre, open-label, randomised trial by Liou, Jyh-Ming, MD, Fang, Yu-Jen, MD, Chen, Chieh-Chang, MD, Bair, Ming-Jong, MD, Chang, Chi-Yang, MD, Lee, Yi-Chia, Prof, Chen, Mei-Jyh, MD, Chen, Chien-Chuan, MD, Tseng, Cheng-Hao, MD, Hsu, Yao-Chun, MD, Lee, Ji-Yuh, MD, Yang, Tsung-Hua, MD, Luo, Jiing-Chyuan, Prof, Chang, Chun-Chao, MD, Chen, Chi-Yi, MD, Chen, Po-Yueh, MD, Shun, Chia-Tung, Prof, Hsu, Wen-Feng, MD, Hu, Wen-Hao, MD, Chen, Yen-Nien, MD, Sheu, Bor-Shyang, Prof, Lin, Jaw-Town, Prof, Wu, Jeng-Yih, MD, El-Omar, Emad M, Prof, Wu, Ming-Shiang, Prof

“…Summary Background Whether concomitant therapy is superior to bismuth quadruple therapy or 14-day triple therapy for the first-line treatment of Helicobacter…”
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Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis by Ko, Chun-Jung, Huang, Cheng-Chung, Lin, Hsin-Ying, Juan, Chun-Pai, Lan, Shao-Wei, Shyu, Hsin-Yi, Wu, Shang-Ru, Hsiao, Pei-Wen, Huang, Hsiang-Po, Shun, Chia-Tung, Lee, Ming-Shyue

“…Dysregulation of androgen signaling and pericellular proteolysis is necessary for prostate cancer progression, but the links between them are still obscure. In…”
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High-dose Dual Therapy Is Superior to Standard First-line or Rescue Therapy for Helicobacter pylori Infection by Yang, Jyh-Chin, Lin, Chun-Jung, Wang, Hong-Long, Chen, Jin-De, Kao, John Y, Shun, Chia-Tung, Lu, Chien-Wei, Lin, Bor-Ru, Shieh, Ming-Jium, Chang, Ming-Chu, Chang, Yu-Ting, Wei, Shu-Chen, Lin, Lin-Chih, Yeh, Wen-Chun, Kuo, Jen-Shin, Tung, Chien-Chih, Leong, Yew-Loong, Wang, Teh-Hong, Wong, Jau-Min

“…Background & Aims The efficacy of treatment of Helicobacter pylori infection has decreased steadily because of increasing resistance to clarithromycin,…”
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Recurrence Outcomes Less Favorable in T1 Rectal Cancer than in T1 Colon Cancer by Chang, Li‐Chun, Shun, Chia‐Tung, Lin, Been‐Ren, Sanduleanu, Silvia, Hsu, Weng‐Feng, Wu, Ming‐Shiang, Chiu, Han‐Mo

“…Background With the implementation of screening programs worldwide, diagnosis of early‐stage colorectal cancer steadily increased, including T1 cancer. Current…”
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Tissue diagnosis necessary for small endoscopic ultrasound‐suspected gastric gastrointestinal stromal tumors 2 cm or less in size: A prospective study focusing on the endoscopic incisional biopsy by Wong, Shenq‐Jie, Wang, Hsiu‐Po, Shun, Chia‐Tung, Chen, Chien‐Chuan, Han, Ming‐Lun, Chen, Jiann‐Hwa, Huang, Chung‐Tsui, Cheng, Tsu‐Yao

“…Background and Aim The small endoscopic ultrasound (EUS)‐suspected gastric gastrointestinal stromal tumors (GISTs), gastric subepithelial tumors at the…”
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Sequential versus triple therapy for the first-line treatment of Helicobacter pylori : a multicentre, open-label, randomised trial by Liou, Jyh-Ming, MD, Chen, Chieh-Chang, MD, Chen, Mei-Jyh, MD, Chen, Chien-Chuan, Chang, Chi-Yang, MD, Fang, Yu-Jen, MD, Lee, Ji–Yuh, MD, Hsu, Shih-Jer, MD, Luo, Jiing-Chyuan, MD, Chang, Wen-Hsiung, MD, Hsu, Yao-Chun, MD, Tseng, Cheng-Hao, MD, Tseng, Ping-Huei, MD, Wang, Hsiu-Po, MD, Yang, Ueng-Cheng, Prof, Shun, Chia-Tung, Prof, Lin, Jaw-Town, Prof, Lee, Yi-Chia, Dr, Wu, Ming-Shiang, Dr Prof

“…Summary Background Whether sequential treatment can replace triple therapy as the standard treatment for Helicobacter pylori infection is unknown. We compared…”
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Sudomotor innervation in transthyretin amyloid neuropathy: Pathology and functional correlates by Chao, Chi-Chao, Huang, Cho-Min, Chiang, Hao-Hua, Luo, Kai-Ren, Kan, Hung-Wei, Yang, Naomi Chu-Chiao, Chiang, Hao, Lin, Whei-Min, Lai, Shu-Mei, Lee, Ming-Jen, Shun, Chia-Tung, Hsieh, Sung-Tsang

“…Objective Autonomic neuropathy is a major component of familial amyloid polyneuropathy (FAP) due to mutated transthyretin, with sudomotor failure as a common…”
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Endocarditis Pathogen Promotes Vegetation Formation by Inducing Intravascular Neutrophil Extracellular Traps Through Activated Platelets by Jung, Chiau-Jing, Yeh, Chiou-Yueh, Hsu, Ron-Bin, Lee, Chii-Ming, Shun, Chia-Tung, Chia, Jean-San

“…BACKGROUND—Endocarditis-inducing streptococci form multilayered biofilms in complex with aggregated platelets on injured heart valves, but the host factors…”
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The possible role of sirtuin 5 in the pathogenesis of apical periodontitis by Yang, Cheng‐Ning, Lin, Sze‐Kwan, Kok, Sang‐Heng, Wang, Han‐Wei, Lee, Yuan‐Ling, Shun, Chia‐Tung, Chi, Chih‐Wen, Yang, Hsiang, Hong, Chi‐Yuan

“…Objectives We investigated the relation between expression of sirtuin 5 (SIRT5) in osteoblastic cells and progression of apical periodontitis. The role of…”
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Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma by Liu, Yuan-Ling, Yang, Pei-Ming, Shun, Chia-Tung, Wu, Ming-Shiang, Weng, Jing-Ru, Chen, Ching-Chow

“…Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading cause of cancer death worldwide. Drug treatments for HCC have been largely…”
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Metabolic syndrome and smoking may justify earlier colorectal cancer screening in men by Chang, Li-Chun, MD, MSc, Wu, Ming-Shiang, MD, PhD, Tu, Chia-Hung, MD, MSc, Lee, Yi-Chia, MD, PhD, Shun, Chia-Tung, MD, Chiu, Han-Mo, MD, PhD

“…Background Gender, smoking, and metabolic syndrome (MetS) are important risk factors of colorectal neoplasm. Whether presence of these factors may warrant…”
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Tumor-Associated Macrophage-Induced Invasion and Angiogenesis of Human Basal Cell Carcinoma Cells by Cyclooxygenase-2 Induction by Tjiu, Jeng-Wei, Chen, Jau-Shiuh, Shun, Chia-Tung, Lin, Sung-Jan, Liao, Yi-Hua, Chu, Chia-Yu, Tsai, Tsen-Fang, Chiu, Hsien-Ching, Dai, Yang-Shia, Inoue, Hiroyasu, Yang, Pan-Chyr, Kuo, Min-Liang, Jee, Shiou-Hwa

“…Tumor-associated macrophages (TAMs) and cyclooxygenase-2 (COX-2) are associated with invasion, angiogenesis, and poor prognosis in many human cancers. However,…”
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Mitochondrial Dysfunction Induced by High Estradiol Concentrations in Endometrial Epithelial Cells by Chou, Chia-Hung, Chen, Shee-Uan, Chen, Chin-Der, Shun, Chia-Tung, Wen, Wen-Fen, Tu, Yi-An, Yang, Jehn-Hsiahn

“…Abstract Context A supraphysiological estradiol (E2) concentration after ovarian stimulation is known to result in lower embryo implantation rates in in vitro…”
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Inhibition of Autophagy Enhances Anticancer Effects of Atorvastatin in Digestive Malignancies by YANG, Pei-Ming, LIU, Yuan-Ling, LIN, Yi-Chu, SHUN, Chia-Tung, WU, Ming-Shiang, CHEN, Ching-Chow

“…Preclinical and clinical studies have shown that statins, the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with cholesterol-lowering properties,…”
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