Search Results - "Shumaev, K B"

Electrophilic Signaling: The Role of Reactive Carbonyl Compounds by Kosmachevskaya, O. V., Shumaev, K. B., Topunov, A. F.

“…Reactive carbonyl compounds (RCC) are a group of compounds with clearly pronounced electrophilic properties that facilitate their spontaneous reactions with…”
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Study of Translocation of Stabilized NO Forms through Rat Skin using Electron Paramagnetic Resonance Method by Timoshin, A. A., Shumaev, K. B., Lakomkin, V. L., Abramov, A. A., Ruuge, E. K.

“…We studied the effect of dinitrosyl-iron complexes with N-acetyl-L-cysteine as a thiol-containing ligand (DNIC-Acc) after transdermal administration to rats…”
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Mechanisms of oxidative modification of low density lipoproteins under conditions of oxidative and carbonyl stress by Lankin, V Z, Tikhaze, A K, Kapel'ko, V I, Shepel'kova, G S, Shumaev, K B, Panasenko, O M, Konovalova, G G, Belenkov, Yu N

“…Low-molecular-weight aldehydes (glyoxal, methylglyoxal, 3-deoxyglucosone) generated on autooxidation of glucose under conditions of carbonyl stress react much…”
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Superoxide formation as a result of interaction of L-lysine with dicarbonyl compounds and its possible mechanism by Shumaev, K. B, Gubkina, S. A, Kumskova, E. M, Shepelkova, G. S, Ruuge, E. K, Lankin, V. Z

“…The EPR signal recorded in reaction medium containing L-lysine and methylglyoxal is supposed to come from the anion radical (semidione) of methylglyoxal and…”
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Antioxidant Effect of Carnosine and Carnosine Dinitrosyl Iron Complexes under the Conditions Modeling Peroxidation of Biomolecules by Nasybullina, E. I., Kosmachevskaya, O. V., Shumaev, K. B., Topunov, A. F.

“…— The antioxidant activity of carnosine and of carnosine dinitrosyl iron complexes (DNICs) was studied. A system with metmyoglobin (metMb) or hemin in…”
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The Effect of Peroxynitrite and tert-Butyl Hydroperoxide on Thiol Ligands of Dinitrosyl Iron Complexes by Pugachenko, I. S., Nasybullina, E. I., Kosmachevskaya, O. V., Shumaev, K. B., Topunov, A. F.

“…Low-molecular-weight dinitrosyl iron complexes (DNICs) with thiol-containing ligands are a physiological form for deposit and transport of nitric oxide (NO) in…”
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Effect of Iron–Nitric Oxide Complexes on the Reactivity of Hemoglobin Cysteines by Kosmachevskaya, O. V., Nasybullina, E. I., Shumaev, K. B., Novikova, N. N., Topunov, A. F.

“…Human erythrocyte hemoglobin (Hb) has two reactive cysteines located on the surface of β-subunits. These cysteines play an important role in the adjustment of…”
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Carbonyl Stress in Bacteria: Causes and Consequences by Kosmachevskaya, O. V., Shumaev, K. B., Topunov, A. F.

“…Pathways of synthesis of the α-reactive carbonyl compound methylglyoxal (MG) in prokaryotes are described in this review. Accumulation of MG leads to…”
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Effect of Dinitrosyl Iron Complexes on Platelet Aggregation Induced by HeLa Cervical Carcinoma Cells by Shamova, E. V, Shishlo, L. M, Gorudko, I. V, Aleksandrova, E. N, Cherenkevich, S. N, Shumaev, K. B

“…We studied the effect of dinitrosyl iron complexes with glutathione ligands on platelet aggregation with HeLa tumor cells. It was shown that dinitrosyl iron…”
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Dinitrosyl Iron Complexes with Glutathione Ligands Intercept Peroxynitrite and Protect Hemoglobin from Oxidative Modification by Kosmachevskaya, O. V., Nasybullina, E. I., Shumaev, K. B., Chumikina, L. V., Arabova, L. I., Yaglova, N. V., Obernikhin, S. S., Topunov, A. F.

“…Dinitrosyl iron complexes with glutathione ligands (GS-DNICs) are a physiological form of nitric oxide that is stored and transported in the organism. In…”
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Signal and regulatory effects of methylglyoxal in eukaryotic cells (review) by Kosmachevskaya, O. V., Shumaev, K. B., Topunov, A. F.

“…Methylglyoxal (MG) is one of the physiological glucose metabolites formed in living organisms. The data on the influence of MG on different internal systems of…”
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A Possible Mechanism of the Antioxidant Action of Dinitrosyl Iron Complexes by Shumaev, K. B., Kosmachevskaya, O. V., Grachev, D. I., Timoshin, A. A., Topunov, A. F., Lankin, V. Z., Ruuge, E. K.

“…— The antioxidant effect of dinitrosyl iron complexes (DNICs) was studied in various model systems. DNICs with glutathione ligand (DNIC-GS) effectively…”
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Influence of dicarbonyls on kinetic characteristics of glutathione peroxidase by Lankin, V. Z., Shumaev, K. B., Tikhaze, A. K., Kurganov, B. I.

“…Se-containing glutathione peroxidase (GSH-Px) is one of the key enzymes of the body’s antioxidant system. The kinetic characteristics of GSH-Px (substrate is…”
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Generation of Superoxide Radicals by Complex III in Heart Mitochondria and Antioxidant Effect of Dinitrosyl Iron Complexes at Different Partial Pressure of Oxygen by Dudylina, A L, Ivanova, M V, Shumaev, K B, Ruuge, E K

“…The EPR spin-trapping technique and EPR-oximetry were used to study generation of superoxide radicals in heart mitochondria isolated from Wistar rats under…”
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Interaction of oxoferrylmyoglobin and dinitrosyl-iron complexes by Shumaev, K B, Petrova, N E, Zabbarova, I V, Vanin, A F, Topunov, A F, Lankin, V Z, Ruuge, E K

“…It is shown that dinitrosyl-iron complexes (DNIC) with glutathione can reduce oxoferrylmyoglobin forming on interaction of tert-butyl hydroperoxide and…”
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Methylglyoxal as a scavenger for superoxide anion-radical by Shumaev, K. B., Lankin, V. Z., Konovalova, G. G., Grechnikova, M. A., Tikhaze, A. K.

“…Methylglyoxal at a concentration of 5 mM caused a significant inhibition of superoxide anion radical (O 2 ·- ) comparable to the effect of Tirone. In the…”
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Reductive Nitrosylation of Hemoglobin and Myoglobin and its Antioxidant Effect by Shumaev, K. B., Grachev, D. I., Kosmachevskaya, O. V., Topunov, A. F., Ruuge, E. K.

“…Angeli’s salt is a nitroxyl donor, due to which it can prevent the negative consequences of hemolysis, such as the vasoconstrictive effect of free hemoglobin…”
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Properties of 2-C-Methyl-D-Erythritol 2,4-Cyclopyrophosphate, an Intermediate in Nonmevalonate Isoprenoid Biosynthesis by Ostrovsky, D N, Dyomina, G R, Deryabina, Yu I, Goncharenko, A V, Eberl, M, Shumaev, K B, Shashkov, A S

“…Extraction and purification from the biomass of Corynebacterium ammoniagenes of 2-C-methyl-D-erythritol 2,4-cyclopyrophosphate (MEC) was associated with its…”
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The Effect of Dinitrosyl Iron Complexes with a Ligand Based on N-Acetyl-L-Cysteine under Sublingual Introduction of These Complexes into the Rat Body by Timoshin, A. A., Shumaev, K. B., Lakomkin, V. L., Abramov, A. A., Ruuge, E. K.

“…The effect of dinitrosyl iron complexes with a ligand based on N -acetyl-L-cysteine, a stabilized NO form, via sublingual administration of this compound into…”
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The Effect of Ferroptosis Inductors on Mitochondrial Membranes in the Hearts of Rats by Fefler, A. S., Ivanova, M. V., Shumaev, K. B., Ruuge, E. K.

“…Using optical spectroscopy, we have studied the models of lipid peroxidation in mitochondrial membranes isolated from the hearts of rats. The oxidative…”
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