Search Results - "Shum, Justine"

905 Impact of the cGMP-dependent protein kinase I on the Rho-Kinase 2 signaling pathway and type I Interferon production by Fernandez-Ruiz, Ruth, Shum, Justine, Nln, Ilona, Paredes, Jacqueline L, Niewold, Timothy B

“…BackgroundInterferon (IFN)-α is a key contributor to susceptibility and severe manifestations in systemic lupus erythematosus (SLE). In SLE, the PRKG1…”
Get full text

CSF-1R inhibition attenuates renal and neuropsychiatric disease in murine lupus by Chalmers, Samantha A, Wen, Jing, Shum, Justine, Doerner, Jessica, Herlitz, Leal, Putterman, Chaim

“…Abstract Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease that can affect multiple end organs. Kidney and brain are two of the organs…”
Get full text

Sex Differences in Systemic Lupus Erythematosus: Epidemiology, Clinical Considerations, and Disease Pathogenesis by Nusbaum, Julie S, Mirza, Ibraheem, Shum, Justine, Freilich, Robert W, Cohen, Rebecca E, Pillinger, Michael H, Izmirly, Peter M, Buyon, Jill P

“…Systemic lupus erythematosus (SLE) is a chronic, multiorgan, systemic autoimmune disease that is more common in women than men and is typically diagnosed…”
Get full text

Myeloid NF-κB signaling contributes to pathogenesis of immune-mediated nephritis by Chalmers, Samantha A., Garcia, Sayra, Shum, Justine, Herlitz, Leal, Putterman, Chaim

“…Abstract Immune-mediated glomerulonephritis is a serious end organ pathology that affects patients with systemic lupus erythematosus (SLE). A common murine…”
Get full text

Sex Differences in Systemic Lupus Erythematosus by Nusbaum, Julie S., Mirza, Ibraheem, Shum, Justine, Freilich, Robert W., Cohen, Rebecca E., Pillinger, Michael H., Izmirly, Peter M., Buyon, Jill P.

Get full text

Regional european genetic ancestry predicts type I interferon level and risk of severe viral infection by Nln, Ilona, Shum, Justine, Ghodke-Puranik, Yogita, Tipon, Regine, Triese, Danielle, Amin, Shreyasee, Makol, Ashima, Osborn, Thomas, Chowdhary, Vaidehi, Thanarajasingam, Uma, Wampler Muskardin, Theresa L, Oke, Vilija, Gunnarsson, Iva, Zickert, Agneta, Zervou, Maria I, Boumpas, Dimitrios T, Svenungsson, Elisabet, Goulielmos, George N, Niewold, Timothy B

“…Viral infection outcomes vary widely between individuals, ranging from mild symptoms to severe organ failure and death, and it is clear that host genetic…”
Get full text

The Oxytricha trifallax mitochondrial genome by Swart, Estienne C, Nowacki, Mariusz, Shum, Justine, Stiles, Heather, Higgins, Brian P, Doak, Thomas G, Schotanus, Klaas, Magrini, Vincent J, Minx, Patrick, Mardis, Elaine R, Landweber, Laura F

“…The Oxytricha trifallax mitochondrial genome contains the largest sequenced ciliate mitochondrial chromosome (~70 kb) plus a ~5-kb linear plasmid bearing…”
Get full text