Search Results - "Shum, George C"
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Mitochondria-lysosome contact site dynamics and misregulation in neurodegenerative diseases
Published in Trends in neurosciences (Regular ed.) (01-04-2022)“…Neurons rely heavily on properly regulated mitochondrial and lysosomal homeostasis, with multiple neurodegenerative diseases linked to dysfunction in these two…”
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Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons
Published in Proceedings of the National Academy of Sciences - PNAS (31-10-2023)“…Inter-organelle contact sites between mitochondria and lysosomes mediate the crosstalk and bidirectional regulation of their dynamics in health and disease…”
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Journal Article