Search Results - "Shum, B."

Immuno-oncology approaches in uveal melanoma: tebentafusp and beyond by Gerard, C., Shum, B., Nathan, P., Turajlic, S.

“…Uveal melanoma (UM) is the most common ocular malignancy in adults, associated with the poorest prognosis, with metastatic disease occurring in up to 50% of…”
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Predictive Power of the NSQIP Risk Calculator for Early Post-Operative Outcomes After Whipple: Experience from a Regional Center in Northern Ontario by Jiang, Henry Y., Kohtakangas, Erica L., Asai, Kengo, Shum, Jeffrey B.

“…Background NSQIP Risk Calculator was developed to allow surgeons to inform their patients about their individual risks for surgery. Its ability to predict…”
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Children with Attention Deficit Hyperactivity Disorder Have Impaired Balance Function: Involvement of Somatosensory, Visual, and Vestibular Systems by Shum, Selina B.M., MSc, Pang, Marco Y.C., PhD

“…Objectives To compare standing balance performance and sensory organization of balance control in children with attention deficit hyperactivity disorder…”
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Population pharmacokinetic analysis of mycophenolic acid in renal transplant recipients following oral administration of mycophenolate mofetil by Shum, B., Duffull, S. B., Taylor, P. J., Tett, S. E.

“…Aim  To develop a population pharmacokinetic model for mycophenolic acid in adult kidney transplant recipients, quantifying average population pharmacokinetic…”
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The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation by Shum, Bennett O V, Mackay, Charles R, Gorgun, Cem Z, Frost, Melinda J, Kumar, Rakesh K, Hotamisligil, Gökhan S, Rolph, Michael S

“…The adipocyte fatty acid-binding protein aP2 regulates systemic glucose and lipid metabolism. We report that aP2, in addition to being abundantly expressed by…”
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Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes by Rajalingam, R, Hong, M, Adams, E J, Shum, B P, Guethlein, L A, Parham, P

“…Some pygmy chimpanzees (also called Bonobos) give much simpler patterns of hybridization on Southern blotting with killer cell immunoglobulin-like receptor…”
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Modes of Salmonid MHC Class I and II Evolution Differ from the Primate Paradigm by Shum, Benny P, Guethlein, Lisbeth, Flodin, Laura R, Adkison, Mark A, Hedrick, Ronald P, Nehring, R. Barry, Stet, Rene J. M, Secombes, Christopher, Parham, Peter

“…Rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta) represent two salmonid genera separated for 15--20 million years. cDNA sequences were…”
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Conservation and Variation in Human and Common Chimpanzee CD94 and NKG2 Genes by Shum, Benny P, Flodin, Laura R, Muir, David G, Rajalingam, Raja, Khakoo, Salim I, Cleland, Sophia, Guethlein, Lisbeth A, Uhrberg, Markus, Parham, Peter

“…To assess polymorphism and variation in human and chimpanzee NK complex genes, we determined the coding-region sequences for CD94 and NKG2A, C, D, E, and F…”
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Human diversity in killer cell inhibitory receptor genes by Uhrberg, M, Valiante, N M, Shum, B P, Shilling, H G, Lienert-Weidenbach, K, Corliss, B, Tyan, D, Lanier, L L, Parham, P

“…The presence and expression of killer inhibitory receptor (KIR) and CD94:NKG2 genes from 68 donors were analyzed using molecular typing techniques. The genes…”
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Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans by Khakoo, S I, Rajalingam, R, Shum, B P, Weidenbach, K, Flodin, L, Muir, D G, Canavez, F, Cooper, S L, Valiante, N M, Lanier, L L, Parham, P

“…That NK cell receptors engage fast-evolving MHC class I ligands suggests that they, too, evolve rapidly. To test this hypothesis, the structure and class I…”
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Comparison of Chimpanzee and Human Leukocyte Ig-Like Receptor Genes Reveals Framework and Rapidly Evolving Genes by Canavez, Flavio, Young, Neil T, Guethlein, Lisbeth A, Rajalingam, Raja, Khakoo, Salim I, Shum, Benny P, Parham, Peter

“…The leukocyte receptor complex (LRC) on human chromosome 19 contains related Ig superfamily killer cell Ig-like receptor (KIR) and leukocyte Ig-like receptor…”
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Regulation of osteoclasts by calcitonin and amphiphilic calcitonin conjugates: role of cytosolic calcium by Komarova, S V, Shum, J B, Paige, L A, Sims, S M, Dixon, S J

“…The peptide hormone calcitonin is a potent inhibitor of osteoclastic resorption, but it is unstable and poorly absorbed following oral administration…”
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Isolation of a classical MHC class I cDNA from an amphibian. Evidence for only one class I locus in the Xenopus MHC by Shum, BP, Avila, D, Du Pasquier, L, Kasahara, M, Flajnik, MF

“…The amphibian Xenopus is an ectothermic vertebrate in which the MHC has been studied extensively at the functional, biochemical, and genetic levels. A cDNA…”
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A novel type of class I gene organization in vertebrates: a large family of non‐MHC‐linked class I genes is expressed at the RNA level in the amphibian Xenopus by Flajnik, M.F., Kasahara, M., Shum, B.P., Salter‐Cid, L., Taylor, E., Du Pasquier, L.

“…A Xenopus class I cDNA clone, isolated from a cDNA expression library using antisera, is a member of a large family of non‐classical class I genes (class Ib)…”
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Attenuation of acute xenograft rejection by short-term treatment with LF15-0195 and monoclonal antibody against CD45RB in a rat-to-mouse cardiac transplantation model by HAO WANG, HOSIAWA, Karoline A, GARCIA, Bertha, SHUM, Jeffrey B, DUTARTRE, Patrick, KELWIN, David J, ZHONG, Robert

“…We previously reported that Lewis rat hearts transplanted into BALB/c mice developed typical acute vascular rejection (AVR). The present study was undertaken…”
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Autoimmune Pancreatitis Masquerading as Pancreatic Cancer: when in Doubt, Cut It Out by Jiang, Henry Y., Kohtakangas, Erica L., Mitrovic, Bojana, Asai, Kengo, Shum, Jeffrey B.

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Unique haplotypes of co-segregating major histocompatibility class II A and class II B alleles in Atlantic salmon (Salmo salar) give rise to diverse class II genotypes by Stet, René J M, de Vries, Beja, Mudde, Karin, Hermsen, Trudi, van Heerwaarden, Joost, Shum, Benny P, Grimholt, Unni

“…Sequence-based typing of a breeding population (G1) consisting of 84 Atlantic salmon individuals revealed the presence of 7 Sasa-DAA and 7 Sasa-DAB expressed…”
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Conserved organization of the ILT/LIR gene family within the polymorphic human leukocyte receptor complex by Young, N T, Canavez, F, Uhrberg, M, Shum, B P, Parham, P

“…The human leukocyte receptor complex (LRC) at Chromosome 19q13.4 encodes Ig superfamily proteins which regulate the function of various hematopoietic cell…”
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Upper gastrointestinal and intra-abdominal hemorrhage secondary to diffuse large B-cell gastric lymphoma by Shum, Jeffrey B., MD, Jayaraman, Shiva, MD, Croome, Kris, MD, Quan, Douglas, MD

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Combination pharmacotherapy for the treatment of fibromyalgia in adults by Thorpe, Joelle, Shum, Bonnie, Moore, R Andrew, Wiffen, Philip J, Gilron, Ian

“…Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide. Current pharmacotherapies are often ineffective and poorly…”
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