Search Results - "Shulman, Nicholas J."

The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo by Vincow, Evelyn S., Merrihew, Gennifer, Thomas, Ruth E., Shulman, Nicholas J., Beyer, Richard P., MacCoss, Michael J., Pallanck, Leo J.

“…The accumulation of damaged mitochondria has been proposed as a key factor in aging and the pathogenesis of many common agerelated diseases, including…”
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Autophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective by Vincow, Evelyn S., Thomas, Ruth E., Merrihew, Gennifer E., Shulman, Nicholas J., Bammler, Theo K., MacDonald, James W., MacCoss, Michael J., Pallanck, Leo J.

“…The destruction of mitochondria through macroautophagy (autophagy) has been recognised as a major route of mitochondrial protein degradation since its…”
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Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides by Dai, Dao-Fu, Hsieh, Edward J, Chen, Tony, Menendez, Lorena G, Basisty, Nathan B, Tsai, Lauren, Beyer, Richard P, Crispin, David A, Shulman, Nicholas J, Szeto, Hazel H, Tian, Rong, MacCoss, Michael J, Rabinovitch, Peter S

“…We investigated the protective effects of mitochondrial-targeted antioxidant and protective peptides, Szeto-Schiller (SS) 31 and SS20, on cardiac function,…”
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Skyline Performs as Well as Vendor Software in the Quantitative Analysis of Serum 25-Hydroxy Vitamin D and Vitamin D Binding Globulin by Henderson, Clark M, Shulman, Nicholas J, MacLean, Brendan, MacCoss, Michael J, Hoofnagle, Andrew N

“…Because the chromatographic characteristics are slightly different for peptides and small molecules, we quantitatively analyzed serum concentrations of…”
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Panorama: A Targeted Proteomics Knowledge Base by Sharma, Vagisha, Eckels, Josh, Taylor, Greg K, Shulman, Nicholas J, Stergachis, Andrew B, Joyner, Shannon A, Yan, Ping, Whiteaker, Jeffrey R, Halusa, Goran N, Schilling, Birgit, Gibson, Bradford W, Colangelo, Christopher M, Paulovich, Amanda G, Carr, Steven A, Jaffe, Jacob D, MacCoss, Michael J, MacLean, Brendan

“…Panorama is a web application for storing, sharing, analyzing, and reusing targeted assays created and refined with Skyline, an increasingly popular Windows…”
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Maximizing Peptide Identification Events in Proteomic Workflows Using Data-Dependent Acquisition (DDA) by Bateman, Nicholas W., Goulding, Scott P., Shulman, Nicholas J., Gadok, Avinash K., Szumlinski, Karen K., MacCoss, Michael J., Wu, Christine C.

“…Current analytical strategies for collecting proteomic data using data-dependent acquisition (DDA) are limited by the low analytical reproducibility of the…”
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Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast by Skelly, Daniel A, Merrihew, Gennifer E, Riffle, Michael, Connelly, Caitlin F, Kerr, Emily O, Johansson, Marnie, Jaschob, Daniel, Graczyk, Beth, Shulman, Nicholas J, Wakefield, Jon, Cooper, Sara J, Fields, Stanley, Noble, William S, Muller, Eric G D, Davis, Trisha N, Dunham, Maitreya J, Maccoss, Michael J, Akey, Joshua M

“…To better understand the quantitative characteristics and structure of phenotypic diversity, we measured over 14,000 transcript, protein, metabolite, and…”
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Topograph, a Software Platform for Precursor Enrichment Corrected Global Protein Turnover Measurements by Hsieh, Edward J., Shulman, Nicholas J., Dai, Dao-Fu, Vincow, Evelyn S., Karunadharma, Pabalu P., Pallanck, Leo, Rabinovitch, Peter S., MacCoss, Michael J.

“…Defects in protein turnover have been implicated in a broad range of diseases, but current proteomics methods of measuring protein turnover are limited by the…”
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